Diagnostic Evaluation of Childhood Craniopharyngioma
The results of imaging studies (computerized tomography scans and magnetic resonance imaging [MRI] scans) are often diagnostic for craniopharyngiomas; these tumors tend to occur in typical intracranial locations and intratumoral calcifications are usually present. Some solid tumors without calcification may be confused with other tumor types, such as germinoma or hypothalamic/chiasmatic astrocytoma, and biopsy may be required.[1] Magnetic resonance spectroscopy may be diagnostically helpful in some cases.[2] MRI of the spinal axis is not routinely performed.
Apart from imaging, patients often undergo formal visual examination including visual field evaluation, and endocrine testing.
References
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Harwood-Nash DC: Neuroimaging of childhood craniopharyngioma. Pediatr Neurosurg 21 (Suppl 1): 2-10, 1994.
[PUBMED Abstract]
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Sutton LN, Wang ZJ, Wehrli SL, et al.: Proton spectroscopy of suprasellar tumors in pediatric patients. Neurosurgery 41 (2): 388-94; discussion 394-5, 1997.
[PUBMED Abstract]
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