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Treatment Options for Childhood Central Nervous System Embryonal Tumors
Newly Diagnosed Childhood Medulloblastoma
Newly Diagnosed Childhood Pineoblastoma and Pineal Parenchymal Tumors
Newly Diagnosed Childhood Supratentorial Primitive Neuroectodermal Tumors
Newly Diagnosed Childhood Medulloepithelioma and Ependymoblastoma
Recurrent Childhood Central Nervous System Embryonal Tumors
A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.
Newly Diagnosed Childhood Medulloblastoma
In newly diagnosed childhood medulloblastoma, the tumor itself has not been treated. The child may have received drugs or treatment to relieve symptoms caused by the tumor.
Average risk
Standard treatment of average-risk childhood medulloblastoma is usually surgery followed by radiation therapy to the brain and spinal cord. Sometimes chemotherapy is given at the same time as radiation therapy or after radiation therapy.
Clinical trials are studying new combinations of radiation therapy and chemotherapy.
High risk
Standard treatment of high-risk childhood medulloblastoma is usually surgery followed by radiation therapy to the brain and spinal cord.
Sometimes chemotherapy is given at the same time as radiation therapy or after radiation therapy.
Clinical trials are studying new combinations of radiation therapy and chemotherapy.
Children 3 years old or younger
Standard treatment of childhood medulloblastoma in children 3 years old or younger is usually surgery followed by chemotherapy. Other treatments may include the following:
Treatment of medulloblastoma in children 3 years old or younger is often within a clinical trial. Clinical trials are studying new combinations of chemotherapy with stem cell transplant.
Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with untreated childhood medulloblastoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Newly Diagnosed Childhood Pineoblastoma and Pineal Parenchymal Tumors
In newly diagnosed childhood pineoblastoma or pineal parenchymal tumors, the tumor itself has not been treated. The child may have received drugs or treatment to relieve symptoms caused by the tumor.
Children older than 3 years
Standard treatment of childhood pineoblastoma and pineal tumors in children older than 3 years is usually surgery. It is usually not possible to remove all of the tumor, because of where it is in the brain. Surgery is usually followed by radiation therapy to the brain and spinal cord. Sometimes chemotherapy is given at the same time as radiation therapy or after radiation therapy.
Clinical trials are studying new treatments for high-risk childhood pineoblastoma, including combinations of chemotherapy, radiation therapy, and stem cell transplant.
Children 3 years old or younger
Treatment of pineoblastoma and pineal tumors in children 3 years old or younger may include surgery followed by chemotherapy. Radiation therapy may be given when the child is older.
Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with untreated childhood pineoblastoma and childhood pineal parenchymal tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Newly Diagnosed Childhood Supratentorial Primitive Neuroectodermal Tumors
In newly diagnosed childhood supratentorial primitive neuroectodermal tumors, the tumor itself has not been treated. The child may have received drugs or treatment to relieve symptoms caused by the tumor.
Children older than 3 years
Standard treatment of supratentorial neuroectodermal tumors in children older than 3 years is usually surgery followed by radiation therapy to the brain and spinal cord.
Sometimes chemotherapy is given at the same time as radiation therapy or after radiation therapy.
Children 3 years old or younger
Standard treatment of supratentorial neuroectodermal tumors in children 3 years old or younger, is usually surgery followed by chemotherapy. Other treatments may include the following:
Treatment of supratentorial primitive neuroectodermal tumors in children 3 years old or younger is often within a clinical trial. Clinical trials are studying new combinations of chemotherapy with stem cell transplant.
Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with untreated childhood supratentorial primitive neuroectodermal tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Newly Diagnosed Childhood Medulloepithelioma and Ependymoblastoma
In newly diagnosed childhood medulloepithelioma and ependymoblastoma, the tumor itself has not been treated. The child may have received drugs or treatment to relieve symptoms caused by the tumor.
Children older than 3 years
Standard treatment of childhood medulloepithelioma or ependymoblastoma in children older than 3 years is usually surgery followed by radiation therapy to the brain and spinal cord.
Sometimes chemotherapy is given at the same time as radiation therapy or after radiation therapy.
Children 3 years old or younger
Standard treatment of childhood medulloepithelioma or ependymoblastoma in children 3 years old or younger is usually surgery followed by chemotherapy. Other treatments may include the following:
Treatment of childhood medulloepithelioma or ependymoblastoma in children 3 years old or younger is often within a clinical trial.
Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with childhood ependymoblastoma and childhood medulloepithelioma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
Recurrent Childhood Central Nervous System Embryonal Tumors
Treatment of recurrent childhood CNS embryonal tumors may include the following:
Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent childhood central nervous system embryonal tumor. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.
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