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Childhood Extracranial Germ Cell Tumors Treatment (PDQ®)
Patient Version   Health Professional Version   En español   Last Modified: 06/26/2008



Description






Stage Explanation






Treatment Option Overview






Childhood Mature and Immature Teratomas






Childhood Malignant Testicular Germ Cell Tumor






Childhood Malignant Ovarian Germ Cell Tumor






Childhood Extragonadal Malignant Germ Cell Tumor






Recurrent Childhood Malignant Germ Cell Tumor






To Learn More About Childhood Cancer






Get More Information From NCI






Changes to This Summary (06/26/2008)






About PDQ



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Stage Explanation

Extracranial Germ Cell Tumors
        Stage I
        Stage II
        Stage III
        Stage IV
        Recurrent
Ovarian Germ Cell Tumor
        Stage I
        Stage II
        Stage III
        Stage IV
        Recurrent

Once a germ cell tumor is found (diagnosed), tests will be done to find out if the germ cell tumor is benign or malignant. If the tumor is malignant, more tests will be done to find out if the cancer cells have spread to other parts of the body (staging). In order to stage a germ cell tumor, the patient may undergo a surgical procedure. Knowing the stage of the disease will assist the doctor in effectively planning further treatment.

Extracranial Germ Cell Tumors

The following stages are used for all extracranial germ cell tumors:

Stage I

Cancer has not spread from the tumor to surrounding tissues or lymph nodes and can be surgically removed with no cancer cells remaining.

Stage II

Cancer has spread to surrounding tissues or lymph nodes, and surgery cannot remove all cancer cells from the surrounding tissues.

Stage III

Cancer has spread to surrounding tissues, has affected several lymph nodes, is found in fluid in the abdomen, and surgery cannot remove the entire tumor from the surrounding tissues.

Stage IV

Cancer has spread to other organs in the body.

Recurrent

Recurrent disease means that the cancer has come back (recurred) after it has been treated. It may come back in the original site of the tumor or in another place.

Ovarian Germ Cell Tumor

The following stages are used for ovarian germ cell tumor:

Stage I

Cancer is found in either one or both of the ovaries; it has not spread to the surrounding tissue. Tumor cells may be present in peritoneal (abdominal) fluid.

Stage II

Cancer is found in one or both ovaries and has spread to the uterus, and/or the fallopian tubes (the pathway used by egg cells moving from the ovary to the uterus), and/or other body parts within the pelvis (bladder, rectum, vagina). Tumor cells may be present in abdominal fluid.

Stage III

Cancer is found in one or both ovaries and has spread to lymph nodes or to other body parts inside the abdomen (outside of the pelvis), such as the surface of the liver or intestine.

Stage IV

Cancer is found in one or both ovaries and has spread outside the abdomen or has spread to the inside of the liver.

Recurrent

Recurrent disease means that the cancer has come back (recurred) after it has been treated. It may come back in the ovary or in another place.

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