Agent Name |
ANTU |
Alternative Name |
alpha-Naphthyl thiourea |
CAS Number |
86-88-4 |
Formula |
C11-H10-N2-S |
Major Category |
Pesticides |
Synonyms |
alpha-Naphthyl thiocarbamide; 1-Naphthyl thiourea; alpha-Naphthyl thiourea |
Category |
Rodenticides |
Description |
White crystalline or gray, odorless powder. [rodenticide] |
Comments |
The lethal oral dose in humans is about 4 g/kg; TLV based on thyroid effects and nausea; In high-dose feeding and intraperitoneal injection studies, animals develop liver injury, pleural and pericardial effusions, and pulmonary edema. [ACGIH] |
Restricted |
No ANTU products are registered in the USA. [LaDou, p. 564] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
0.3 mg/m3 |
PEL (OSHA) |
0.3 mg/m3 |
MAK |
0.3 mg/m3, inhalable fraction |
IDLH (NIOSH) |
100 mg/m3 |
Excerpts from Documentation for IDLHs |
Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ANTU. However, based on acute oral toxicity data in humans [Stolman 1969] and animals [Gosselin et al. 1984; Perkow 1971/76], the original IDLH for ANTU (100 mg/m3) is not being revised at this time. |
Adverse Effects |
Hepatotoxin |
Hepatotoxin, Secondary |
IARC Carcinogen |
Not Classifiable |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ALPHA-NAPHTHYLTHIOUREA
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