| Agent Name |
ANTU |
|---|
| Alternative Name |
alpha-Naphthyl thiourea |
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| CAS Number |
86-88-4 |
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| Formula |
C11-H10-N2-S |
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| Major Category |
Pesticides |
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| Synonyms |
alpha-Naphthyl thiocarbamide; 1-Naphthyl thiourea; alpha-Naphthyl thiourea |
|---|
| Category |
Rodenticides |
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| Description |
White crystalline or gray, odorless powder. [rodenticide] |
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| Comments |
The lethal oral dose in humans is about 4 g/kg; TLV based on thyroid effects and nausea; In high-dose feeding and intraperitoneal injection studies, animals develop liver injury, pleural and pericardial effusions, and pulmonary edema. [ACGIH] |
|---|
| Restricted |
No ANTU products are registered in the USA. [LaDou, p. 564] |
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| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.3 mg/m3 |
|---|
| PEL (OSHA) |
0.3 mg/m3 |
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| MAK |
0.3 mg/m3, inhalable fraction |
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| IDLH (NIOSH) |
100 mg/m3 |
|---|
| Excerpts from Documentation for IDLHs |
Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ANTU. However, based on acute oral toxicity data in humans [Stolman 1969] and animals [Gosselin et al. 1984; Perkow 1971/76], the original IDLH for ANTU (100 mg/m3) is not being revised at this time. |
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| Adverse Effects |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ALPHA-NAPHTHYLTHIOUREA
|
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