| Agent Name |
Allethrin |
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| CAS Number |
28057-48-9 |
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| Formula |
C19-H26-O3 |
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| Major Category |
Pesticides |
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| Synonyms |
2-Methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate trans-(+)-; DL-2-Allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one, d-trans-chrysanthemum monocarboxylic ester; d-trans-Allethrin; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl ester, trans-(+)-; d-trans-Chrysanthemic acid of d-allethrone; [ChemIDplus] Trade names include Alleviate, Pynamin, d-Allethrin, d-cisAllethrin, Bioallethrin, Esbiothrin, Pyresin, Pyrexcel, Pyrocide, and trans-Allethrin. [EXTOXNET] |
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| Category |
Pyrethrins/Pyrethroids |
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| Description |
Yellow liquid with a mild aromatic odor; [EXTOXNET] |
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| Sources/Uses |
Used in homes and gardens to kill flies and mosquitoes; The d-trans isomer is a more potent insecticide used to control animal parasites. Sold as mosquito coils, mats, oil formulations, and sprays; [EXTOXNET] |
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| Comments |
Slightly toxic after skin absorption or ingestion with an oral LD50 of 1100 mg/kg in male rats; Liver injury is detected in animal experiments with high oral doses. [EXTOXNET] See Bioallethrin, RN: 584-79-2, with LCLo (rats) = 13,800 mg/m3/4H and a vapor pressure = 0.0000012 mm Hg. [ChemIDplus] Pyrethroids have low toxicity to humans after dermal exposure. Of 573 dermal or ingestion poisoning cases in China, 51 patients had disturbed consciousness and 34 had seizures. Of those, only five were occupationally exposed. Seizures are more commonly related to exposures to fenvalerate, flucythrinate, cypermethrin, deltapermethrin, and fluvalinate. Seizures have not been reported after exposure to permethrin. Pyrethroids may also cause paresthesias after skin contact. Paresthesias (stinging and numbness) usually begin 1-2 hours after contact and resolve within 24 hours. [EPA Pesticides, p. 87-8] Pyrethrins cause liver injury when fed to animals at high doses. [EXTOXNET] |
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| Reference Link |
EXTOXNET PIP - ALLETHRIN |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Adverse Effects |
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| Neurotoxin |
Other CNS Neurotoxin |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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