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Agent Name tert-Amyl methyl ether
Alternative Name TAME
CAS Number 994-05-8
Formula C6-H14-O
Major Category Solvents
Synonyms 1,1-Dimethylpropyl methyl ether ; 2-Methoxy-2-methylbutane ; 2-Methyl-2-methoxybutane ; Methyl 1,1-dimethylpropyl ether ; Methyl tert-amyl ether ; Methyl tert-pentyl ether ; TAME (ether) ; Tertiary amyl methyl ether ; tert-Pentyl methyl ether ; tertiary-Amyl methyl ether; [ChemIDplus]
Category Ethers
Sources/Uses Used as a gasoline additive to reduce emissions; [ACGIH]
Comments Toxicity in animal studies includes CNS depression and increased liver weights; TAME is embryotoxic in high-dose studies of pregnant mice and rats; [ACGIH]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 20 ppm
Vapor Pressure 75 mm Hg
Odor Threshold Low 0.02 ppm
Lethal Concentration LC50 (rats) = >5,400 mg/m3/4H
Explanatory Notes Detection odor threshold from ACGIH;
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Hepatotoxin Hepatotoxin, Secondary
Reproductive Toxin Yes
Links to Other NLM Databases
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: January, 2009