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Agent Name Hexachlorobenzene
Alternative Name HCB
CAS Number 118-74-1
Formula C6-Cl6
Major Category Pesticides
Synonyms Perchlorobenzene; Hexa C.B.; Anticarie; Bunt-cure; Bunt-no-more; CEKU C.B.; No Bunt; Pentachlorophenyl chloride; No Bunt 40; Julian`s carbon chloride; No Bunt 80; Sanocide; Smut-Go; Amatin; Co-op Hexa; Granox NM; Snieciotox; [ChemFinder]
Category Organochlorine Pesticides
Sources/Uses Was used as a pesticide until 1965; it may be produced as a waste product from chloralkali and wood-preserving plants or as an emission from municipal incinerators; it can bioaccumulate in lichens, fish, marine animals, birds, and caribou; [ATSDR ToxFAQs] Used as a seed fungicide to prevent common and dwarf bunt on wheat; [EXTOXNET]
Comments In Turkey between 1955-1958, about 4000 people developed a cutaneous porphyria syndrome six months after eating bread contaminated by hexachlorobenzene. [Ladou, p. 214] "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414]
Restricted Banned from use as a pesticide in the U.S. [EXTOXNET]
Reference Link EXTOXNET PIP - HEXACHLOROBENZENE
Exposure Assessment
Skin Designation (ACGIH) Yes
Bioaccumulates Yes
TLV (ACGIH) 0.002 mg/m3
Half Life Half-life in rats and monkeys was measured at 3-4 months and 2 1/2 to 3 years, respectively. [EXTOXNET]
Reference Link ATSDR - ToxFAQs - Hexachlorobenzene
Adverse Effects
Hepatotoxin Hepatotoxin, Secondary
Other Poison Organochlorine Pesticide
IARC Carcinogen Possible Carcinogen
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: HEXACHLOROBENZENE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: September, 2008