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Agent Name Tributyl phosphate
CAS Number 126-73-8
Formula C12-H27-O4-P
Major Category Other Classes
Synonyms Butyl phosphate; Butyl phosphate, ((BuO)3PO); Butyl phosphate, tri-; Celluphos 4; Disflamoll TB; MCS 2495; Phosphoric acid, tributyl ester; TBP; Tri-N-butylphosphate; Tri-n-butyl phosphate; Tributilfosfato [Italian]; Tributoxyphosphine oxide; Tributyl phosphate; Tributyle (phosphate de) [French]; Tributylfosfaat [Dutch]; Tributylfosfat [Czech]; Tributylphosphat [German]; Tributylphosphate; [ChemIDplus]
Category Phosphorus Compounds
Description Colorless to pale-yellow, odorless liquid; [NIOSH]
Sources/Uses Used as a solvent, plasticizer, and antifoam agent; [ACGIH] Used as an antifoaming agent (concrete, textile, and paper industries); [HSDB]
Comments Animals given repeated oral doses show pathological changes of the urinary bladder epithelium. [ACGIH] If left on clothing, can cause reddening of skin; [CHRIS] Irritating to the skin, eyes, and respiratory tract; [ICSC]
Exposure Assessment
BEI Cholinesterase activity in red blood cells = 70% of individual's baseline sampling time discretionary
Skin Designation (ACGIH) No
TLV (ACGIH) 0.2 ppm
PEL (OSHA)5 mg/m3
MAK 1 ppm
IDLH (NIOSH) 30 ppm
Excerpts from Documentation for IDLHs "Human data: Nausea and headache have been reported in workers exposed to 15 mg/m3 (1.4 ppm) [Mastromatteo 1964]." [NIOSH]
Vapor Pressure 0.00113 mm Hg
Lethal Concentration LC50 (rats) = 28,000 mg/m3/1H
Explanatory Notes Flash point = 146 deg C;
Flammability (NFPA) 1: must be preheated
Adverse Effects
Dermatotoxin Skin Burns
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: TRIBUTYL PHOSPHATE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Processes Industrial Processes with risk of exposure:





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Last updated: January, 2009