| Agent Name |
Tetrachloronaphthalene |
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| CAS Number |
1335-88-2 |
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| Formula |
C10-H4-Cl4 |
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| Major Category |
Other Classes |
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| Synonyms |
Halowax; Nibren wax; Seekay wax; [NIOSH] |
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| Category |
Halowaxes |
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| Description |
Colorless to pale-yellow solid with an aromatic odor; [NIOSH] |
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| Sources/Uses |
"There are no known commercial uses for purified individual isomers of di-, tri-, tetra-, penta-, hexa-, or heptachloronaphthalene." [HSDB] |
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| Comments |
Chlorinated naphthalenes may be absorbed through the skin. They cause liver injury and hyperkeratosis in experimental animals. Penta- and hexachloronaphthalene may cause in exposed workers acne-like lesions that itch severely. Tri-, tetra-, and octachloronaphthalene are non-acnegenic under the conditions of industrial use. Nine occupational fatalities from chlorinated naphthalene poisoning have been reported. Most cases of intoxication among cable workers, assemblers, and laborers involve either penta- or hexachloronaphthalene. A nonfatal case of toxic hepatitis was reported in an 18 year old female who was soldering electrical condensers. [ACGIH] Acne-form dermatitis is listed as an adverse effect for all of the halowaxes except trichloronaphthalene in the NIOSH Pocket Guide. May cause liver injury; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| Bioaccumulates |
Yes |
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| TLV (ACGIH) |
2 mg/m3 |
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| PEL (OSHA) |
2 mg/m3 |
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| Excerpts from Documentation for IDLHs |
Animal data: It has been stated that tetrachloronaphthalene has been shown to be less toxic to the liver than more highly chlorinated derivatives of naphthalene [ACGIH 1986]. . . . Basis for revised IDLH: Due to a lack of relevant acute toxicity data, the IDLH for tetrachloronaphthalene remains "Unknown." |
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| Vapor Pressure |
1 x 10 -06 mm Hg |
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| Explanatory Notes |
Flash point = 210 deg C; |
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| Adverse Effects |
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| Dermatotoxin |
Chloracne |
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| Hepatotoxin |
Hepatotoxin, Primary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: TETRACHLORONAPHTHALENE
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