| Agent Name |
Pindone |
|---|
| Alternative Name |
2-Pivalyl-1,3-indandione |
|---|
| CAS Number |
83-26-1 |
|---|
| Formula |
C14-H14-O3 |
|---|
| Major Category |
Pesticides |
|---|
| Synonyms |
tert-Butyl valone; 1,3-Dioxo-2-pivaloylindan; Pival; Pivalyl; 2-Pivalyl-1,3-indandione; [NIOSH] |
|---|
| Category |
Rodenticides, Anticoagulant |
|---|
| Description |
Bright-yellow powder with almost no odor. [rodenticide]; [NIOSH] |
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| Sources/Uses |
Used as an anticoagulant rodenticide and an insecticide; [ACGIH] |
|---|
| Comments |
A vitamin K antagonist that inhibits prothrombin; [ACGIH] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TLV (ACGIH) |
0.1 mg/m3 |
|---|
| PEL (OSHA) |
0.1 mg/m3 |
|---|
| IDLH (NIOSH) |
100 mg/m3 |
|---|
| Excerpts from Documentation for IDLHs |
Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for pindone. Therefore, the revised IDLH for pindone is 100 mg/m3 based on acute oral toxicity data in humans [Gosselin et al. 1984] and animals [Gaines 1960; Klimmer 1971; Perkow 1971/1976] and an analogy to warfarin [ACGIH 1971] which has a revised IDLH of 100 mg/m3. |
|---|
| Adverse Effects |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| Nephrotoxin |
Yes |
|---|
| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PINDONE
|
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