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Agent Name Nitric acid
CAS Number 7697-37-2
Formula H-N-O3
Major Category Toxic Gases & Vapors
Synonyms Acide nitrique [French]; Acido nitrico [Italian]; Acido nitrico [Spanish]; Acidum nitricum; Aqua fortis; Azotic acid; Azotowy kwas [Polish]; Engraver's acid; Hydrogen nitrate; Kyselina dusicne [Czech]; Nital; Nitric acid; Nitrous fumes; Nitryl hydroxide; RFNA; Red fuming nitric acid; Salpetersaeure; Salpetersaure [German]; Salpeterzuuroplossingen [Dutch]; [ChemIDplus] UN2031; UN2032
Category Acids
Description Colorless, yellow, or red, fuming liquid with an acrid, suffocating odor. [Note: Often used in an aqueous solution. Fuming nitric acid is concentrated nitric acid that contains dissolved nitrogen dioxide.]; [NIOSH]
Sources/Uses Used primarily to produce ammonium nitrate fertilizer; also used in metal cleaning, etching, and manufacturing explosives; [ACGIH]
Comments Liquid causes second or third degree burns after short contact; [CHRIS] Solutions >30% are highly corrosive to skin; Solutions <30% are corrosive; [Quick CPC] Nitrogen dioxide and nitric oxide are usually present as hazards whenever nitric acid is used. Occupational exposure may lead to acute pneumonitis and pulmonary edema. [ACGIH] May cause erosion of teeth enamel; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) No
TIH Yes
TLV (ACGIH) 2 ppm
STEL (ACGIH) 4 ppm
PEL (OSHA) 2 ppm
IDLH (NIOSH) 25 ppm
Excerpts from Documentation for IDLHs Other animal data: Rats receiving a single exposure to 63 mg/m3 nitric acid (24 ppm) exhibited no apparent adverse effects [Diggle and Gage 1954].
Vapor Pressure 63.1 mm Hg
Odor Threshold Low 0.27 ppm
Lethal Concentration LC50 (rats) = 67 ppm (NO2)/4H
Explanatory Notes Odor threshold from AIHA; The Guide from the Emergency Response Guidebook is for "nitric acid, fuming."
Half Life No reports found; [TDR, p. 937]
Flammability (NFPA) 0: will not burn
Adverse Effects
Toxic Pneumonitis Yes
Dermatotoxin Skin Burns
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: NITRIC ACID  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:
Activities Activities with risk of exposure:





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Last updated: September, 2008