| Agent Name |
Monomethyl aniline |
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| CAS Number |
100-61-8 |
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| Formula |
C7-H9-N |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
(Methylamino)benzene; Aniline, N-methyl-; Benzeneamine, N-methyl-; Methylphenylamine; Monomethylaniline; N-Methylaminobenzene; N-Methylbenzenamine; N-Methylphenylamine; N-Monomethylaniline; N-Phenylmethylamine; [ChemIDplus] UN2294 |
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| Category |
Amines, Aromatic |
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| Description |
Yellow to light-brown liquid with a weak, ammonia-like odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent and in organic synthesis; [ACGIH] Solvent for organic reactions and for nitrocellulose; [HSDB] |
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| Comments |
Methemoglobinemia and liver injury occur in animals exposed to high concentrations over a period of weeks and months. There are no reports of human poisoning by monomethyl aniline. Listed in table of "Industrial Chemicals for Which Methemoglobin Formation is the Principal Cause of Toxicity"; [ACGIH] Can induce methemoglobinemia; [ICSC] |
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| Exposure Assessment |
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| BEI |
Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH] |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
0.5 ppm |
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| PEL (OSHA) |
2 ppm |
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| MAK |
0.5 ppm |
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| IDLH (NIOSH) |
100 ppm |
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| Excerpts from Documentation for IDLHs |
Other animal data: It has been reported that a dog survived 50 seven�hour exposures to 86 ppm [Treon et al. 1949]. |
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| Vapor Pressure |
0.3 mm Hg |
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| Odor Threshold Low |
1.6 ppm |
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| Odor Threshold High |
2 ppm |
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| Explanatory Notes |
Odor threshold from AIHA; Flash point = 175 deg F; |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Primary |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-METHYLANILINE
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