| Agent Name |
Titanium dioxide |
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| CAS Number |
13463-67-7 |
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| Formula |
O2-Ti |
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| Major Category |
Metals |
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| Synonyms |
1385RN 59; 1700 White; 234DA; 500HD; 63B1 White; A 200 (pigment); A 330 (pigment); A-FN 3; A-Fil; A-Fil Cream; AK 15 (pigment); AMT 100; AMT 600; AUF 0015S; Aerolyst 7710; Aerosil P 25; Aerosil P 25S6; Aerosil P 27; Aerosil T 805; Amperit 780.0; Atlas white titanium dioxide; Austiox R-CR 3; B 101 (pigment); BR 29-7-2; Bayer R-FD 1; Bayertitan A; Bayertitan AN 3; Bayertitan R-FD 1; Bayertitan R-FK 21; Bayertitan R-FK-D; Bayertitan R-KB 2; Bayertitan R-KB 3; Bayertitan R-KB 4; Bayertitan R-KB 5; Bayertitan R-KB 6; Bayertitan R-U 2; Bayertitan R-U-F; Bayertitan R-V-SE 20; Bayertitan T; Bistrater L- Blend White 9202; Brookite; C 97 (oxide); C-Weiss 7 [German]; C.I. 77891; C.I. Pigment White 6; CG-T; CI 77891; CI Pigment white 6; CL 310; Cab-O-Ti; Calcotone White T; Cosmetic Hydrophobic TiO2 9428; Cosmetic Micro Blend TiO2 9228; Cosmetic White C47-5175; Cosmetic White C47-9623; E 171; Flamenco; Hombitan; Hombitan R 101D; Hombitan R 610K; Horse Head A-410; Horse Head A-420; Horse Head R-710; Horse head a-410; Horse head a-420; Horse head r-710; KH 360; Kronos; Kronos 2073; Kronos RN 40P; Kronos RN 56; Kronos cl 220; Kronos titanium dioxide; Levanox White RKB; Orgasol 1002D White 10 Extra Cos; P 25 (oxide); Pigment White 6; R 680; Rayox; Ro 2; Runa ARH 20; Runa ARH 200; Runa RH20; Rutile; Rutiox CR; Ti-Pure; Ti-Pure R 901; Ti-pure R 900; Tichlor; Tin dioxide dust; Tiofine; Tiona T.D.; Tiona td; Tioxide; Tioxide A-DM; Tioxide AD-M; Tioxide R XL; Tioxide R-CR; Tioxide R-SM; Tioxide R.XL; Tioxide RHD; Tioxide RSM; Tipaque; Tipaque R 820; Titafrance; Titan White; Titandioxid (sweden); Titandioxid [Swedish]; Titania; Titanic anhydride; Titanic oxide; Titanium White; Titanium dioxide; Titanium oxide; Titanium oxide (TiO2); Titanium oxide (VAN); Titanium peroxide; Titanium peroxide (TiO2); Titanium(IV) oxide; Titanox; Titanox 2010; Titanox ranc; Trioxide(s); Tronox; Unitane; Unitane 0-110; Unitane 0-220; Unitane O-110; Unitane O-220; Unitane OR 450; Unitane OR 650; Unitane OR-150; Unitane OR-340; Unitane OR-342; Unitane OR-350; Unitane OR-540; Unitane OR-640; Uniwhite AO; Uniwhite KO; Uniwhite OR 450; Uniwhite OR 650; Zopaque; Zopaque LDC; [ChemIDplus] UN8027 |
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| Category |
Metals, Inorganic Compounds |
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| Description |
White, odorless powder; Found naturally in the minerals rutile, anatase (or octahedrite), brookite, ilemnite (FeTiO3), and perovskite (CaTiO3). [Merck Index] |
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| Sources/Uses |
Pigment or filler in paints, paper, foods, ceramics, and pharmaceuticals; Used in welding rod coatings; [ACGIH] Rutile TiO2 is used as a semiconductor in the electronics industry. [Rom, p. 537] |
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| Comments |
A study of 1,576 workers in the U.S. exposed to TiO2 for more than one year used incidence data from 1956 through 1985. Mortality data was available from the company for the years 1935 through 1983. There was no excess of lung cancer or chronic respiratory disease and no cases of pulmonary fibrosis. [Rom, p. 537-8] Cases of pulmonary fibrosis associated with exposure to TiO2 have been reported, but the reactions may have been caused by silica present as contamination. [Hendrick, p. 180-1] No listed effects of short-term or long-term exposure; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
10 mg/m3 |
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| PEL (OSHA) |
15 mg/m3, total dust |
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| MAK |
1.5 mg/m3, respirable fraction |
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| IDLH (NIOSH) |
5000 mg/m3 |
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| Excerpts from Documentation for IDLHs |
Basis for revised IDLH: The available toxicological data contain no evidence that an acute exposure to a high concentration of titanium dioxide would impede escape or cause any irreversible health effects within 30 minutes. |
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| Explanatory Notes |
mp = 1855 degrees C; [Merck Index] |
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| Adverse Effects |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: TITANIUM DIOXIDE
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