| Agent Name |
Dimethyl sulfoxide |
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| CAS Number |
67-68-5 |
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| Formula |
C2-H6-O-S |
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| Major Category |
Solvents |
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| Synonyms |
DMS-70; DMS-90; DMSO; Deltan; Demasorb; Demavet; Demeso; Demsodrox; Dermasorb; Dimethyl sulfoxide; Dimethyl sulphoxide; Dimethyli sulfoxidum [INN-Latin]; Dimethylsulfoxide; Dimethylsulfoxyde [INN-French]; Dimetil sulfoxido [INN-Spanish]; Dimetilsolfossido [DCIT]; Dimexide; Dipirartril-tropico; Dolicur; Doligur; Domoso; Domoso (Veterinary); Dromisol; Durasorb; Gamasol 90; HSDB 80; Hyadur; Infiltrina; M 176; Methane, sulfinylbis-; Methyl sulfoxide; Methylsulfinylmethane; Rimso-5; Rimso-50; SQ 9453; Somipront; Sulfinylbis(methane); Syntexan; Topsym; [ChemIDplus] |
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| Category |
Other Solvents |
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| Description |
Colorless liquid that is odorless or has a slight odor of sulfur, garlic, or oysters; [CHEMINFO] |
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| Sources/Uses |
Used as a pharmaceutical, a solvent for polymerization and chemical extractions, a paint remover, a preservative for organ transplantation; Occurs naturally in ground water and in grains, vegetables, and many other foods; [CHEMINFO] Used as a solvent for many organic compounds; Also used in industrial cleaners; [HSDB] |
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| Comments |
A skin and eye irritant; May cause CNS depression after inhalation, ingestion, or skin absorption of high doses; Long term use may cause adverse effects to the liver and blood; [ICSC] Rats experienced "no significant effects" after inhalation of 200 mg/m3 (62.8 ppm) for 30 days. After skin absorption, humans may experience garlic odor on the breath, headache, nausea, and dizziness. DMSO enhances the absorption of other drugs. [CHEMINFO] Health effects after inhalation of high concentrations may include headache, dizziness, and sedation. [CAMEO] Can cause nonimmunologic contact urticaria; [Kanerva 2004, p. 102] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
0.61 mm Hg |
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| Lethal Concentration |
LC50 (rat) >1600 mg/m3 (aerosol)/4 hr; [CHEMINFO] |
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| Explanatory Notes |
MP= 65 degrees F; BP = 372 degrees F; |
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| Flammability (NFPA) |
2: high ambient temperature required |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIMETHYL SULFOXIDE
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