| Agent Name |
Methyl isoamyl ketone |
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| CAS Number |
110-12-3 |
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| Formula |
C7-H14-O |
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| Major Category |
Solvents |
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| Synonyms |
2-Hexanone, 5-methyl-; 2-Methyl-5-hexanone; 5-Methyl-2-hexanone; Isoamyl methyl ketone; Isopentyl methyl ketone; Ketone, methyl isoamyl; MIAK; Methyl isoamyl ketone; Methyl isopentyl keton; [ChemIDplus] 5-Methylhexan-2-one; [CAMEO] UN2302 |
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| Category |
Ketones |
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| Description |
Colorless, clear liquid with a pleasant, fruity odor; [NIOSH] |
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| Sources/Uses |
Uesd as a solvent for nitrocellulose, cellulose acetate, butyrate, acrylics, high-solid coatings, and vinyl copolymers; [HSDB] |
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| Comments |
A skin and eye irritant; [CAMEO] Inhalation of high concentrations may cause kidney injury and unconsciousness; [ICSC] Causes liver injury after repeated high-dose inhalation exposures of rats; [HSDB] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
50 ppm |
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| PEL (OSHA) |
100 ppm |
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| MAK |
10 ppm |
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| Vapor Pressure |
5.77 mm Hg |
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| Odor Threshold Low |
0.01 ppm |
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| Odor Threshold High |
0.04 ppm |
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| Lethal Concentration |
LC50 (rats) = 3,813 ppm/6h |
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| Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.013 ppm); Flash point = 36 deg C; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Nephrotoxin |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 5-METHYL-2-HEXANONE
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