| Agent Name |
Chromium trioxide |
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| Alternative Name |
Chromium anhydride |
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| CAS Number |
1333-82-0 |
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| Formula |
Cr-O3 |
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| Major Category |
Metals |
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| Synonyms |
Anhydride chromique [French]; Anidride cromica [Italian]; Chrome (trioxyde de) [French]; Chromia (CrO3); Chromic acid, solid; Chromic anhydride; Chromic oxide; Chromic(VI) acid; Chromium oxide; Chromium oxide (Cr4O12); Chromium oxide (CrO3); Chromium trioxide; Chromium(6+) oxide; Chromium(6+) trioxide; Chromium(VI) oxide; Chromsaeureanhydrid [German]; Chromtrioxid [German]; Chroomtrioxyde [Dutch]; Chroomzuuranhydride [Dutch]; Cromo(triossido di) [Italian]; Monochromium trioxide; Puratronic chromium trioxide; Sintered chromium trioxide; [ChemIDplus] UN1463 |
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| Category |
Metals, Inorganic Compounds |
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| Description |
Dark red to brown crystals, flakes, or powder; [HSDB] |
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| Sources/Uses |
Used in chromium plating, copper stripping, and aluminum anodizing; also used to inhibit corrosion, to develop photographs, to purify oil and acetylene, to harden microscopic preparations, and to oxidize organic chemicals; [HSDB] |
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| Comments |
Highly corrosive to skin; [Quick CPC] Chromium trioxide (chromic acid) is a water-soluble hexavaent chromium compounds. A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; May cause skin sensitization, kidney injury, and asthma after prolonged contact; [ICSC] See "Chromium and compounds." |
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| Reference Link |
HSDB |
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| Exposure Assessment |
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| BEI |
Chromium(VI), water-soluble fume: Total Cr in urine = 10 ug/L (increase during shift) or 25 ug/L (end of shift at end of workweek) |
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| Skin Designation (ACGIH) |
No |
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| Bioaccumulates |
Yes |
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| TLV (ACGIH) |
0.05 ppm, as Cr |
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| PEL (OSHA) |
0.005 ppm, as Cr(VI) |
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| Lethal Concentration |
LC50 (rats) = 167 mg/m3/4 H; [CHEMINFO] |
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| Explanatory Notes |
Melting point = 197 degrees C; [HSDB] The Guide from the Emergency Response Guidebook is for "Chromium trioxide, anhydrous." |
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| Flammability (NFPA) |
0: will not burn |
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| Adverse Effects |
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| Asthma |
Yes |
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| Lung Cancer |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Skin Sensitizer |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Nephrotoxin |
Yes |
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| Reproductive Toxin |
Yes |
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| IARC Carcinogen |
Known Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CHROMIC TRIOXIDE
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