| Agent Name |
Iodochlorhydroxyquin |
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| Alternative Name |
Clioquinol |
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| CAS Number |
130-26-7 |
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| Formula |
C9-H5-Cl-I-N-O |
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| Major Category |
Other Chemicals |
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| Synonyms |
5-Chloro-7-iodo-8-hydroxyquinoline; 5-Chloro-7-iodo-8-quinolinol; 5-Chloro-8-hydroxy-7-iodoquinoline; Chloroiodoquin; Chlorojodochin; Cifoform; Dioquinol; Quin-O-Creme; 7-Iodo-5-chloroxine; Lekosept; Domeform; Clioquinol; Amebil; Alchloquin; Amoenol; Bactol; Barquinol; Budoform; Chinoform; Eczecidin; Enteroquinol; Entero-Septol; Entero-Vioform; Enterozol; Entrokin; Hi-Enterol; Iodochlorhydroxyquin; Iodochloroxyquinoline; Iodoenterol; Nioform; Quinambicide; Rometin; Quinoform; Vioform; Iodochlorohydroxyquinol; Iodochlorohydroxyquinoline; Chloroiodoquine; 7-Iodo-5-chloro-8-hydroxyquinoline; Cliquinol; Emaform; Entero-bio form; Enterum locorten; Hydriodide-enterol; Iodenterol; Vioform n.n.r.; [ChemFinder] |
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| Category |
Pharmaceuticals |
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| Sources/Uses |
Used as a medicinal cream, ointment, or powder; [HSDB] |
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| Comments |
Allergic contact dermatitis reported in patients using this antibiotic topically; [Marks, p. 123-4] Can cause contact urticaria; [Kanerva 2004, p. 102] An epidemic of subacute myelo-optico-neuropathy occurred in Japan from 1956 until 1970. Approximately 10,000 cases were reported with visual impairment, lower extremity paresthesias and weakness, and other symptoms. Symptoms resolved after the oral medication was discontinued. Neurotoxicity developed in patients who received total doses greater that 750 mg/day for four weeks. [HSDB] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CLIOQUINOL
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