| Agent Name |
Diethylene glycol monobutyl ether |
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| CAS Number |
112-34-5 |
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| Formula |
C8-H18-O3 |
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| Major Category |
Solvents |
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| Synonyms |
2-(2-Butoxyethoxy)ethanol; BUCB; Butoxy diethylene glycol; Butoxydiethylene glycol; Butoxydiglycol; Butoxyethoxyethanol; Butyl Ethyl Cellosolve; Butyl carbitol; Butyl diglycol; Butyl digol; Butyl dioxitol; Diethylene glycol butyl ether; Diethylene glycol monobutyl ether; Diethylene glycol n-butyl ether; Diethylene gylcol monobutyl ether; Diglycol monobutyl ether; Dowanol DB; Ektasolve DB; Ethanol, 2,2'-oxybis-, monobutyl ether; Ethanol, 2-(2-butoxyethoxy)-; Glycol ether DB; Jeffersol DB; O-Butyl diethylene glycol; Poly-Solv DB; [ChemIDplus] |
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| Category |
Glycol Ethers |
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| Description |
Colorless liquid with a mild pleasant odor; [CAMEO] |
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| Sources/Uses |
Used as a solvent and diluent for polymers, resins, coatings, inks, cleaners, and metalworking fluids; [HSDB] |
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| Comments |
In animal studies, no genotoxic or mutagenic effects and no acute adverse effects after exposure to 18 ppm; No evidence of liver, kidney, blood, or reproductive toxicity in humans; [Sullivan, p. 1204] A mild skin irritant and severe eye irritant that is absorbed through the skin; [CHS, p. 164] The toxicity of diethylene glycol ethers is lower than that of the ethylene glycol ethers. Animal studies: Can cause central nervous system depression, liver, and kidney injury; also potentially toxic to bone marrow; [HSDB] A skin and eye irritant; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| MAK |
100 mg/m3 |
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| Vapor Pressure |
0.02 mm Hg |
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| Explanatory Notes |
Flash point = 78 deg C; |
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| Flammability (NFPA) |
2: high ambient temperature required |
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| Adverse Effects |
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| Anemia |
Anemia, Aplastic |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Nephrotoxin |
Yes |
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| Reproductive Toxin |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIETHYLENE GLYCOL MONO-N-BUTYL ETHER
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