| Agent Name |
Bronopol |
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| CAS Number |
52-51-7 |
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| Formula |
C3-H6-Br-N-O4 |
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| Major Category |
Other Chemicals |
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| Synonyms |
2-Bromo-2-nitropropane-1,3-diol; 2-Nitro-2-bromo-1,3-propanediol; Bronidiol; Bronocot; Bronopol; Bronopolu [Polish]; Bronopolum [INN-Latin]; Bronosol; Bronotak; Lexgard bronopol; Onyxide 500; beta-Bromo-beta-nitrotrimethyleneglycol; [ChemIDplus] UN3241 |
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| Category |
Preservatives/Disinfectants |
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| Sources/Uses |
Bronopol is a preservative and antiseptic used in cosmetics and topical medications. It is used as a preservative in paints, textiles, cooling towers, humidifiers, and hide processing. [Marks, p. 136-7] Used as a preservative/antiseptic in cleaning agents, paints, and shampoos and other hair products; [Kanerva, p. 474-8] |
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| Comments |
Bronopol is a skin sensitizer. Cosmetic preparations contain concentrations of 0.01% to 0.02%. Significant irritant effects are seen when the concentration reaches 1% or greater. [Marks, p. 136-7] Skin sensitization reported in dairy workers and a veterinarian using a gel for ultrasound examinations; [Kanerva, p. 1132-3] Can cause nonimmunologic contact urticaria; [Kanerva 2004, p. 103] A skin, eye, and respiratory tract irritant; A skin sensitizer; [ICSC] |
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| Reference Link |
Milk recorder dermatitis |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
126000 mm Hg |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: BRONOPOL
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