Expertise Provided:
Need medical regulatory advice or market assessment for your SBIR project planning? Will your SBIR project ultimately end up as an FDA submission? That is an important part of your business plan, risk assessment and commercialization strategy. We help you with your regulatory assessment. We also assist with technical writing of your grant regulatory sections and medical project business plan assessment. We also offer guidance to your company in setting up FDA required quality design controls and QA systems, especially important if you are going into clinical trials as part of your Phase II SBIR project. We have provided "key personel" in over ten SBIR projects that needed to address regulatory issues early. http://www.scibiz.net

Expertise Provided:
20/20 GeneSystems has a extensive experience in manufacture of and research with the membranes. The first LGS product, (BioMax MultiBlot kit) was developed under a CRADA with the NCI (see http://ttb.nci.nih.gov/success.html)

Expertise Provided:
Developing interactive, multimedia learning applications for a wide range of government and commercial clients. We have experience in cognitive psychology, learning theory, user needs analysis, and the actual design, development and testing of learning solutions, whether they be distributed over the Internet/intranets or on single workstations. Our staff has much experience and success in preparing successful SBIR proposals, conducting research and developing successful products. We further are experienced in developing data management software, helping clients to deal with large volumes of data.

Expertise Provided:
Located in Birmingham AL area. 3DM provides prototyping, design, and manufacturing services for medical devices, especially orthopaedic surgical instrumentation and implants.

See croquetproject.org for more info.

Expertise Provided:
In search of opportunity to collaborate with educational institutions or researchers on SBIR/STTR projects that utilize collaborative 3D technologies for training in the medical field.

See croquetproject.org for more info.

Expertise Provided:
In search of opportunity to collaborate with anyone (education/industry/small business) on SBIR/STTR Projects. We provide expertise in engineering and hard sciences (physics, chemistry, geology, hydrology, planetary science, mineralogy, and more) project support. Priority given to research with benefits to human space exploration but will consider contracts for interesting projects. Please see our brochure http://www.4frontierscorp.com/dev/assets/4Frontiers%20Services%20Brochure.pdf.

Don’t miss the menu on the left of our consultants page for more details. http://www.4frontierscorp.com/areasoffocus/consultancy.php.

Or just email VP Joe Palaia IV, joe@4FrontiersCorp.com or call our Florida office 727-845-4011.

Expertise Provided:
We build custom software applications and infrastructured required by the bioscience and biotechnology industries to efficiently collaborate and share their work among each other and the public. Using software engineering best practices (RUP), our solutions are developed with usability, scalability, and maintainability as driving forces. Our main area of expertise is providing web applications for advanced technology and high throughput researchers using leading edge, object-orientated technologies (J2EE, UML, XML, Web Services). We share a common passion to advance medicine and science through our contribution of state-of-the-art software development.

More information can be found at: http://www.3d-doctor.com or http://www.ablesw.com/3d-doctor

Expertise Provided:
We are a company that processes Chiropractic claims for our clients and have the expertise and knowledge of many Chiropractic fraudulent and abusive behavior schemes.

Expertise Provided:
Our core technology is the ability to keep mammalian retinas alive in culture for extend periods of time. This allows us to screen compounds/chemicals/pesticides for toxicity or determine the effects of extreme environmental hazards (e.g., lasers, strong sunlight, or chemical/biological weapons). As a full-service biotech company, we also have a growing clinical advisory group and drug development capabilities, so would be able to take drugs from screening into humans.

The U.S. medical cost for diabetic foot complications exceeds $6 billion annually. In spite of reimbursement to Providers through the Medicare Therapeutic Foot Bill, a clinical standard has not been developed that confirms and monitors the effectiveness of footwear and foot orthotics to prevent diabetic foot re-ulceration.

Expertise Provided:
Novel process improvement.

Expertise Provided:
Application development using handheld, wireless technology in areas of clinical trial (oncology) and patient outcomes and satisfaction data collection. Over 20 years experience in integrating wireless bar code tracking systems for process control and inventory control for large manufacturing and medical companies.

Expertise Provided:
Chemical conjugations, targeted toxins, antibody development, fluorescent tagging, biotinylation, and secondary conjugates. Saporin technology provides molecular surgery tools for scientists to unravel complex neural systems. Extensive experience in pain and brain disorders (e.g. Alzheimer’s, Parkinson’s, epilepsy).

Advanced Targeting Systems will work with your organization to prepare SBIR/STTR applications or to support projects in other NIH, NSF, or DOD-funded programs. With over 12 years of grant-funded projects, ATS will be a valuable partner. The ATS catalog and quarterly newsletter, Targeting Trends, are posted at: http://www.ATSbio.com.

Expertise Provided:
From new concepts to implementation of ultra efficient, secure, and reliable transmission mechanism based on 3 patents and 2 most recent patent applications.

Expertise Provided:
Remote wireless, low-power network sensor technology. We have developed a business plan for a new medical device to assist both eldercare providers and individual senior citizens.

Expertise Provided:
I am specialist clinician in the field of Periodontology and dental Implantology. I have two offices , which can be utilize to conduct research or provide tissues, subjects, data in the area of epidemiology, laser technology, Evaluation of X-ray, biological film, local delivery of chemotheraputic drugs, oral lesions, oral cancer, genetic/ epigenetic studies on tissue obtained from the patient before , after and on patient who are on recall program.

Expertise Provided:
Akouo specializes in research in individual and organizational behavior modification, community health and development, cultural and linguistic practices and policies in health care and human services, and development of measurement and interventions for behavior modification related to healthcare and wellness.

Expertise Provided:
Aktiv-Dry LLC has expertise and intellectual property for formulating and manufacturing particles in the 1-10 micron size range. This range is suitable for pulmonary delivery by inhalation. We have ongoing projects and significant expertise with live virus vaccines, proteins, and immunoglobulins. We also have expertise in inexpensive dry powder inhalers.

Expertise Provided:
Offering employee assistance and collaboration with management on work life issues.

Expertise Provided:
Expertise provided are the development of innovative products using botanicals as nutraceuticals. Bioinformatics development of health care products

Expertise Provided:
Design of chemical libraries for screening, data mining. Molecular modeling, virtual screening, pharmacophore identification, structural bioinformatics. Programming, C/C++, JAVA. Software evaluation and commercialization.

Expertise Provided:
Nanotechnology based electron source to improve the resolution of the x-ray imaging for biomedical/medical structures. We have the ability to develop near-uniform energy distributed electron source with durable and stable performance for X-ray instruments. We have expertise to work from scentific concept design to engineering realization.

Expertise Provided:
1. Protein drug design and manufacture in CHO cells;

2. Serum-free suspension culture and medium;

3. Bioreactor system easy to use;

Multiaxis force measurement technology for biomechanics measurement

Multiaxis servohydraulic testing machines for joint motion simulation

Expertise Provided:
AMTI has expertise in the following areas and is interested in developing collaborative reasearch efforts in the same:

Multiaxis force measurement technology for biomechanics measurement

Multiaxis servohydraulic testing machines for joint motion simulation

Our website is http://www.amti.biz/default.htm

Expertise Provided:
In vivo model of human angiogenesis, anti-androgen screening, prostate cancer stem cells. See http://www.androbiosys.com.

Expertise Provided:
ANSYA provides the following services: 1) Development of communications and data collection tools and software systems - including systems integration, wireless/PDA/Tablet PC custom applications, website development, CD-ROM/Multimedia, Flash based animation, etc. 2) Clincial trials services - protocol development, data collection tools, etc. 3) Data/Statistical analytical services

Expertise Provided:
AEI is a qualified US small business offering over 50 years expertise in the design, development and manufacture of mechanical, electronic, and optical systems. We are a truly vertically integrated manufacturing and engineering company. We have experienced grant writers and have successfully competed for SBIR funds.

Expertise Provided:
Expertise in the field of healthcare consulting, quality assurance, and healthcare software implementation process improvements. Provide consultation and guidance to physicians offices or medical facilities in the selection and implementation of an Electronic Health Record

http://www.applicaconsultinggroup.com

Additionally we have a fundamental understanding of chlorogenic acids role in glucose metabolism and would like to validate this with adequate subjects.

Expertise Provided:
Applied Food Sciences has full product analysis and profiling capabilities. Our core strength is finding all natural food based compounds which have additional health beneftis then finding methods to manfucture pure grades of these compounds for food and beverage applications.

Expertise Provided:
Archimedes Analytical has a core competancy in polymeric and elastomeric materials failure analysis, reformulation and engineering for parts with custom properties. Our specialty is in customized interdisciplinary testing of polymeric materials, such as, thermal, mechanical, wear, bond line failures etc. Our range of hands experience extends from Intellectual Property to production.

Expertise Provided:
Argosy's main capability is development, integration, and implementation of wireless solutions, particularly Bluetooth wireless network solutions that make mobility and location-based applications and services possible. We can take responsibility for the complete life cycle of projects or any stage of the project life cycle including analysis, feasibility, requirements, development, integration, testing, or deployment. Argosy also develops innovative solutions using generalized process management software. We specialize in solving data or process challenges quickly through prototyping. Our solutions integrate existing systems, applications, or devices, and provide incremental, low-risk path to standards-based compliant systems. http://www.argosycorp.com/

Expertise Provided:
We design and synthesize conformationally constrained peptides and conjugates of these creative materials that can be used as unusual immunogens to produce antibodies that target bends, turns and helices in proteins.

Expertise Provided:
Novel full function hardware device that allows hands-free operation of computer awaiting commercialization and we have the technical talent to go along with it (patent #5,603,065). Three interfaces (novice, advanced, freeform) partially story-boarded and ready for usability scenario testing on actual device. http://windjewel.com

Expertise Provided:
Advanced biocompatible joining of Ceramics to Metals. Using brazing or glass sealing. Aluminum Oxide to Titanium, Niobium, Zirconium Oxide to Titanium. Commercially available alloys or proprietary. History of work in Implantable Devices and Medical Components.

Expertise Provided:
Pharmaceutical Drug Compounding Services from a pharmacy with over 40-years experience.

Expertise Provided:
Low cost, durable, portable and miniaturized microarray readers and optical systems, for laboratory and field use.

Expertise Provided:
Cost effective methods of screeing for Depression, Anxiety, Social Anxiety Disorder, Alcoholism and Erectile Dysfunction. All in Primary Care settings

Method for testing, data collection, software, screeing in primary care settings, identification of comorbid patients. Development of software to assist clinicians in scoring and norming results of commonly used assessment instruments. See our website http://www.auroramd.com and then email me at lars@auroramd.com

Expertise Provided:
Axontologic provides expertise and software tools for life science knowledge discovery, adverse drug event recognition and surveillance, lead identification and lead optimization for drug discovery, and literature mining for gene, protein, and drug function/properties.

http://www.axontologic.com

Expertise Provided:
15 years in Fetal Heart acoustics. Was co-patenter (my concept, idea, and plan for development coupled with NASA's great scientists & technical skills that made 'our dream' a reality) with NASA on an ambulatory and passive fetal heart rate monitor. Have three patents on same and have a new patent pending regarding an invention for fetal heart monitoring I need to submit for a STTR.

-Molecular diagnostic testing for microbial drug resistance in environmental and clinical samples from: South America and Africa.

Expertise Provided:
World wide Infectious disease: outbreak; policy; testing, and vaccine platforms cost-benefit analysis, and quality control.

We provide various biomedical and pharmaceutical humanitarian platforms in Africa.

Rural health advocacy.

Expertise Provided:
BCR Diagnostics has developed a biosensing system (LEXSAS) using microbial spores as detectors. A laboratory prototype of the LEXSAS has been used for real time (3-5 min) detection of bacterial contamination in human platelets used for transfusion.

Expertise Provided:
Develop and produce video and interactive (CD-ROM, DVD, web, etc.) educational programs. Have both a creative team of writers, application developers, producers, computer graphic designers and programmers as well as a complete audio and video production facility complete with videographers, audio engineers, video editors, directors, etc. We have successful experience applying for SBIR grants that use electronic media to help communicate and educate.

Expertise Provided:
Drug formulation and development. Positive in vitro results for our cancer therapy, Nocobal.

Expertise Provided:
20 years experience in neuro rehabilitation, PHD neuroscience, experience with motion analysis (kinematics & EMG); currently conducting a RCT comparing two different physical therapy treatments

Expertise Provided:
Interested in collaborating with highly experienced researcher/s passionate about enhancing resiliency and reducing risk factors in children and families. See concepts for the initial pilot study at www.ToddlerTeachingKits.com . Preliminary data utilized a small and undiverse sample while patent pending status was obtained. Now research with a larger and more diverse sample will reveal truly representative findings. Preschool Teaching Kits and School Age Teaching Kits are also patent/s pending and will be accessible soon.

Expertise Provided:
Innovation and intellectual property development; R&D, in latex and synthetic polymers; some prototype development and potential manufacturing depending on prodcut configuration. Proprietary technology platform for multiple layer and antimicrobial thin films to provide active protection against transmission of pathogens. Infection control problem solving.

Expertise Provided:
We have developed a high-throughout, low-cost, fast, high-resolution and automated micro-channel electrophoresis system for DNA genotyping work. Please check our website at www.biocal.com for more information.

Expertise Provided:
Design of instruments for acquisition and processing of images and electrograms (ECG, EMG, ENG, EEG, ECoG, EBGoG). Experience in automatic detection of tissue morphology using high frequency ultrasound. Experience in EMG, EEG and effector/limb kinematics as they apply to movement disorders, epilepsy and catstrophic event prediction. Application of control systems and signal processing for implantable medical devices, imaging devices with emphasis on applying frequency domain concepts in the time domain to reduce computational overhead. Modeling of linear and nonlinear dynamic systems, chaotic biological processes and robotic kinematics for artificial limbs. http://www.bioelectricsolutions.com

We are a small research and development company that can perform cell and tissue culture based studies as well as biochemical analysis. Our laboratory is also set up to run DNA microarray analysis.

Expertise Provided:
Bioinventions LLC has expertise in the general area of antioxidant biochemistry with particular emphasis on vitamin E homologues. We offer state-of-the-art analytical facilities with the ability to measure: (1) vitamin E (and its oxidation products) in human and animal tissues, diets, botanical samples and in cultured cells; (2) biochemical indices for oxidative stress (lipid hydroperoxides, isoprostanes, oxidized low density lipoprotein). We are also fully equipped to assist in the design and execution of animal experiments as well as clinical studies.

Expertise Provided:
Drug Discovery:

BioLeap’s technology is a very accurate and scalable method for first-principles modelling of how water and chemical fragments interact with macromolecules, including DNA & RNA. The technology uniquely accounts for: Ø Rigorous free energies, including orientational entropy Ø Multibody solvent structures Ø 3-way protein-water-ligand interactions Ø Structured/embedded waters

This information allows us to predict the rank order of binding.

DESCRIPTION Biopac Systems, Inc. manufactures physiological data acquisition systems for physiological education and research. We manufacture data collection systems composed of hardware (including sensors) and software for real-time analysis, display and post-processing of physiological data.

GENERAL EXPERTISE Manufacturing capability (sensors to systems) Software development ability (Analysis, Presentation and GUI) Physiological data acquisition Novel physiological sensors Human and animal monitoring Physiological education Modular physiological research equipment Multi-channel recording

SPECIFIC EXPERTISE Cardiovascular Hemodynamics Pharmacological Investigations Pulmonary Function Exercise Physiology Biomechanics Remote Monitoring Sleep Studies Cardiology Telehealth Non-invasive Monitoring Psychophysiology Neurophysiology Cellular Physiology

SPECIFIC PHYSIOLOGICAL MEASUREMENT CAPABILITES EEG, ECG, EMG, EOG, EGG, Pulse Oximetry, Blood Pressure, Temperature, Blood Flow, Cardiac Output, Bioimpedance, Force, Strain, Displacement, Plethysmography, Stimulus/Response, Evoked Responses, Oxygen Consumption, Carbon Dioxide Production, Laser Doppler Flow, Respiration, Electrodermal Activity

Expertise Provided:
Speech technology R&D, including automatic speech recognition, speech synthesis, and voice transformation, focused on communication disorders.

Expertise Provided:
Label-free high-sensitivity biochip, based on proprietary waveguide design, suitable for multiplexed field testing and monitoring applications.

Expertise Provided:
Blue Sky Biotech has decades of commerical experience in all common "gene to protein" research-scale reagent production. Blue Sky has expertise in Molecular Biology (such as cloning & mutegenesis), Cell Culture & Fermentation, Protein Purification, and some assay development. Recombinant host expression systems such as yeast, mammalian, insect, and bacteria are routine for BLue Sky.

Expertise Provided:
http://www.blueh2o.us

Blue Water Technologies researches, develops and designs cost-effective treatment plants (both fixed and mobile) for removal of heavy metals, selenium, arsenic and phosphorus from drinking water and wastewater. Blue Water has a significant research capability in this area as well as commercialization capability.

Expertise Provided:
We provide innovative vision systems for color/gloss measurement and surface defects detection and classification. It is applied to skin imaging.

http://www.bossanovatech.com

Expertise Provided:
Technical consulting and custom software design, GIS, client/server and web database application development for data collection and analysis. System development, implementation, enhancement and integration. Over 20 years of experience developing systems for governmental clients.

Expertise Provided:
Bracy Analytics utilizes SAS software to its full extent while performing statistical modeling, data mining, and OLAP processing. We create server-side web-based SAS applications for clients and researchers. We automate processes that improves ROI and we collaborate on publications in the healthcare industry. Please visit our site for more information: http://www.bracy-analytics.com

Expertise Provided:
Skilled Orthopedic Surgeon and Materials Engineer principals have patent pending design and procedure for a contactless hip replacement implant. Need University or company to take from concept to product. Some Internal funding available.

Expertise Provided:
1) Cell measurment systems that identify viable but not culturable cells

2) Cell separation systems that separate viable but not culturable cells from non-viable cells and debris

Our technology addresses a clear need. We simply need the right biological experience and facilities on board.

Expertise Provided:
We have several methods for long term storage and distribution of highly perishable, living products that have potential applications for cells, natural tisues and engineered tissues. We have had a very high success rate with past SBIR/STTR proposals.

Our cell and tissue preservation research is focused primarily on developing products and processes employing low temperature biology to substantially improve the quality and cost-effectiveness of cell and tissue storage and transportation. CTS preservation technologies potentially impact a huge US patient population and the broad potential for U.S. economic benefits extrapolates to about one-half of the existing total health care costs. The CTS technology platform for cell and tissue preservation is based on four complementary strategies for optimization of cell survival. These include solutions designed to optimize cell survival during storage at refrigeration temperatures (0-10°C), strategies to deliver non-toxic cryoprotectants into cells, avoidance of damaging ice formation, and development of prototype freeze drying methods. Technology/Product Information: The products are preservation methods and formulations. We are actively seeking companies to partner with us and utilize our preservation technologies for their products and distribution areas. The target markets are cell and tissue research & toxicology target products including preservation and distribution of preserved cells, human cell and tissue banking for research distribution, allogeneic tissue banking, medical cell therapies. There are also many small niche market opportunities for research, toxicology testing and diagnostic kit products.

Expertise Provided:
Able to make custom eyeglass applications for special research and clinical studies, including high prisms, powers and colored plano and prescription filters for a multitude of vision disorders.

Expertise Provided:
Chemical synthesis, mainly for small organic molecules.

This includes custom synthesis and chemistry contract research in scales ranging from mg to kg.

We provide synthesis based on developed protocols or literature methods, but also can develop novel procedures if not readily available.

Expertise on the synthesis of standard compounds (including isotope-labeled compounds such as metabolites), intermediate, starting material, analogs for SAR studies, library building blocks and templates, etc.

Very time- and cost-efficient.

Expertise Provided:
Training, technical assistance, capacity building, curriculum development, program development, research-to-practice.

Areas of specialty include: Complimentary and Alternative Natural Medicine Mind/Body Integration Hypnosis, Aromatherapy, Reiki, Iridology, Sound & Color Therapy

22 years of Traditional Medicine background via Pharmaceutical Industry.

Expertise Provided:
Areas of specialty include: Complimentary and Alternative Natural Medicine Mind/Body Integration Hypnosis, Aromatherapy, Reiki, Iridology, Sound & Color Therapy

22 years of Traditional Medicine background via Pharmaceutical Industry.

Expertise Provided:
The Technology and Business Center of The College of William & Mary provides multiple resources for clients.

The Center provides support at multiple levels for entrepreneurs and early stage technology companies by systematically connecting business owners, visionaries, and inventors with required services and other technology startups and executives.

The Center helps these companies by providing a system of support services that includes service provider consulting, mentorship, community building, access to financial and management expertise, infrastructure support, and timely information about government and private programs and research.

View at http://www.wm.edu/economic_development/tbc.php

Expertise Provided:
Our expertise is in synthetic organic and medicinal chemistry. We have a complete chemistry laboratory including many HPLCs, Mass Spectrometer and an NMR. We also have expertise in the life sciences including neuroscience, cancer and diabetes.

Expertise Provided:
We provide expertise in advanced scientiific data architectures, distrbuted hosting and rapid heterogeneous data integration and Adaptive Data Relationship Management a background method. Collectively we have over 60 years advanced systems integration, design and development. J2EE, UNIX/LINUX, Webservices, GRID computing. See Business Week article dated June 3, 2002 titled, “Who Needs Supercomputers?” see link: http://www.businessweek.com/magazine/content/02_22/b3785111.htm that was our team.

Expertise Provided:
Complex systems modeling, analysis, and control.

Expertise Provided:
Novel Segmentation Algorithms cuts days/months from doing precise/accurate segmentation from scalar and vector (Color) volumetric Data. Looking for specific clinical superspeciality bellwether practitioners willing to help shape our core modeling technology for their specific needs; will create novel business ventures for each market niche.

Expertise Provided:
Cost-effective IT consultants, RFID projects, software development, database architecture.

Expertise Provided:
Custom synthesis of small organic molecules and chemical service development. http://www.creativechemlabs.com/

Expertise Provided:
Polyethylene glycol or PEG reagent synthesis Chemical linking biological macromolecules using PEG cross-linking reagents

Expertise Provided:
Clinical study management including clinical project management and monitoring. Remote study management using electronic data collection tools such as Interactive Voice Response (IVR) for patient diaries, automated fax scanning (FAX) for direct entry of case report forms, montoring report forms and surveys, web-enabled online forms (WEB) for direct entry using a web browser or Adobe PDF forms; we provide online access to databases, reports and CRF images. Regulatory and invetigational drug packaging capabilities. Ophthalmology, Pain, Asthma, Urology, Crohn's Disease, Anti-infectives and a variety of other areas. See http://www.criteriumusa.com for more information.

http://www.biom8tion.com

Expertise Provided:
Biomation provides unique industrial grade biotechnological process automation platforms. We also provide automation consultation services ranging from requirements definition, through design and build to verification and validation of software and processes. In addition, Biomation can build customized software for processing/storing bioinformatic data as well as scheduling automated processes.

http://www.biom8tion.com

Expertise Provided:
Have expertise in multiphase flows, viscous flows and particulate calculations. Have used commercial and in-house fully tested computational fluid dynamic solvers.

Expertise Provided:
The adjustable keyboard support stand is unique in that it incorporates a forearm support that reduces back and shoulder strain. Adjustable for height and angle, the fixture is easily adjusted for use with a wheelchair, from a chair to a desk or work station, or in bed, while reclined. I have received Provisional Patent and we are currently doing a Patent Search.

Additionally we would like to talk with a company or university that can conduct efficacy and biocompatibility studies for human testing in addition to trials / consumer testing.

Expertise Provided:
Patent holder of a unique birth control medical device.

Expertise Provided:
Violence prevention program implementation. Research design and implementation of surveys, focus groups and program evaluations.

Expertise Provided:
Dental Management of the Renal Transplant Recipient. We are expanding to include dialysis and all organ transplant.

Expertise Provided:
Inventor of high level hydrogen peroxide based oral health formula

Patent pending

CDC recommends active ingredient

Expertise Provided:
Expertise in fluid management & pumping systems (Disposables & Devices) for both sterile and non-sterile applications.

We offer engineering skills & capabilities for medical device disposable research & design (Mechanical, Electrical, Software, Systems, Biomedical Engineering) as well as Chemistry & Physics.

Industry experience in Cardiac Assist, In-Vitro Diagnostics, Blood Banking, and Genomics.

Refer to http://www.designmentor.com for further information

Clinical, identification of specific medical problems that could be impacted by a new diagnostic method or test. Also, relevant specimen acquision.

Expertise Provided:
Clinical diagnostic product R&D, clinical evaluation. Proteomic analysis (mass spec), differential expression profiling.

Expertise Provided:
Enterprise Application Integration (past experience with NCI, NHLBI and NIAID); Wireless Data Integration (Handheld based SAE reporting both online and offline mechanisms); Scientific Application Development in Clinical Trials, Patient Care Systems and Bioinformatics. http://www.digitalinfuzion.com

Expertise Provided:
On Demand high Preformance computing solutions. We match buyers and sellers of computational resources in an online exchange while managing protocol and security. We can deliver cost effective solutions to researchers’ short term supercomputing needs. Our focus is in Simulation & Bioinformatics, but we are open to assisting any needs.

For more information, visit us at http://www.dimagi.com

Expertise Provided:
Dsiher is a design and development company with expertise in product design and development for the automotive, consumer product and medical industries.

Expertise Provided:
I am also available to provide photography services required for Marketing and Corporate photography, including Annual Reports, Environmental portraits, and Customer Events

Expertise Provided:
We provide clinical site monitoring, regulatory compliance, data management, biostatistics, medical/technical writing for clinical research. Besides our headquarters in Rockville, MD, we have 10 regional Clinical Research Associate sites to cover the entire US. We have been a Clinical Research Organization since 1994. Please visit our website for more information (www.dpclinical.com) or contact Young Kim at 301-294-6226 or ykim@dpclinical.com.

Expertise Provided:
The oral health formula is under patent pending status; has been previously tested and proves to be most effective in elimating harmful microbes from dentures and toothbrushes. Comparison tests conducted at UNC included Efferdent; regular hydrogen peroxide and, and subject formula.

Expertise Provided:
We are software consultancy specializing in developing distributed and mobile applications in the healthcare industry. Our consultants have over 10 years of experience and experts in J2EE, J2ME, CORBA, XML and other Object-Oriented technologies. They are also very knowledgeable in HL7 and CORBAMed specifications.

Assays that can be micronized to be utilized in 96/384 well plates utilizied in liquid handling high-throughput robotic screening equipment such as Zymarks Allegro & Staccato systems.

Experience in successfully writing and obtaining government grants and other funding.

Expertise Provided:
We can provide robotic access to mining our planets vast eukaryotic biodiversity to identify new drug and other product leads (http://www.dyadic-group.com/wt/dyad/hts).

Additionally we utilize the same discovery microorganism to over-express genes to provide sufficient proteins for animal studies, clinical trials and for other non pharma applications (http://www.dyadic-group.com/wt/dyad/gene_expression).

Finally, we have the large scale expertise and capacity to produce commercially viable quantities of proteins in up to 150,000 liter fermenters (http://www.dyadic-group.com/wt/dyad/manufacturing).

We have an integrated approach to utilizing robotics to rapidly discover, develop and manufacturing proteins originating from the genomes of the millions of living things making up our planets vast biodiversity (http://www.dyadic-group.com/wt/home).

Expertise Provided:
I have an invention of an organ tissue shock and vibration isolation transport enclosure system, designed to prevent tissue trauma during transit from helicopter "chop" and aircraft randoms, high impact shock of 200+ g's, as well as 48 hour steady state control at 34 +/- 2 F ice water temperature. It features a two- mass, two-shock mount (external and internal) 12 degree of freedom isolation system, which results in a highly effective "tuned mass damping" attenuation isolation device, with outputs of less than 0.35 g's and shocks of <5-9 g's for 12+ foot drop, or per NAVY MIL Specs. My company is a small business in shock and vibration R&D. You may see a CAD rendering of the invention on page 3 of my web site: www.descorp.com. I have a working prototype model ready for formal feasibility testing. I can send more information to interested parties of the design and performance todate.

Expertise Provided:
We are a small business interesting in collaborating on research investigations targeting children and families, professional development systems and social science research, mentor-coaching, etc.

Experience in making training videos is definitely preferred.

Expertise Provided:
Effective Educational Practices, LLC is a consulting company offering professional development to educators working in elementary, middle, and high schools. We specialize in provding educators with empirically validated strategies for serving students who display challenging behaviors. For more information check out our website at http://www.successfulschools.org

Expertise Provided:
Thermal Imaging. Lots of experience imaging medical devices used clinically, in a lab, or in production. Gain tens of thousands of temperature measurements of your prototype at 60Hz.

See companies served at validations.biz. Numerous testimonials on the web from leading medical device companies.

Expertise in experimental design. Achieve your goals with the fewest number of experiments.

Expertise Provided:
Materials Science and Processing, Ceramic Processing Laboratory and experience in SBIR research projects.

Sensor systems developer requiring advanced signal processing capabilities in a minimal footprint.

Expertise Provided:
We are a premier provider of advanced software and design services to the global embedded market for miniaturized sensor systems. Our offerings are especially focused on sensor systems development and digital signal processing implementations. We have strong experience in medical device development and unmatched expertise in design reusability and product line architecture. Our website is http://www.EmINENTmicro.com.

Expertise Provided:
We are a company that helps commercialize advanced technolgies into production. These technolgies include MEMS packaging, Flip Chip assembly, die attach/ wire bonding, as well as surface mount technology devices (BGAs, CSPs). http://www.engentaat.com/

We are interested in working with partners who have interesting small molecules (chiral compounds, unique compounds, multiple compounds, ect.). We are very interested in learning more about performing mass spectrometric analysis of small to large proteins with our current mass spectrometers. Protein analysis using LC-MS/MS via ESP+/- ionization is a fairly new area of expertise but one that has been accepted in the scientific community. A collaborator with this expertise and interest in developing a protein analytical technique and metabolic profiling on a production-scale is needed. We are also interested in developing assays for a cocktail of drugs or biomarkers in a single biological sample.

Expertise Provided:
Eno is a science-based company built on trace analysis that performs method development and method validation for small molecules via LC-MS/MS and HRGC-HRMS. We have experience in assaying for novel compounds and also have experience with extracting novel compounds from complex biological matrices. Our scientists also have experience in chiral separations and sub pg/ml detections limits of these compounds.

We would like to assist academic labs that require specialized analytical experience in order to demonstrate the therapeutic promise of their novel drug(s) in early feasibility studies while expanding our scientific growth as individuals and as a company.

Expertise Provided:
Expertise in - cognitive models of intelligence - behavior-based models of intelligence - knowledge representation and reasoning - robotics, UAVs - cryptology - network intrusion detection - air traffic management research - distributed simulation, Cybele, HLA - agent-based programming

Expertise Provided:
Small medical device venture that has patent pending prototype devices to better enable patient fluid management of hemodialysis, congestive heart failure, and elderly patients in hydration management. The technology enhances patient self care.

(see www.digistraw.com)

Expertise Provided:
Unique solubilized formulations of anti-oxidant formulations with enhanced bioavailability.

For additional information about our capabilities, please visit us at http://www.formatech.com

Expertise Provided:
1) Therapeutic antisense probes with dual tagged Fluorescein dyes. 2) Custom oligonuleotide probes with modifications like Biotin etc., 3) Taqman Probes and Fluorescent Probes.

Expertise Provided:
1. Bioinformatics: retrieve the sequences of your up-or-down genes. 2. Use our exclusive Exon-Intron toll: ExonTracker(TM)(http://www.geneharbor.com/products/exontracker.html) to design PCR primers which amplify fragments spanning exon junctions for the purpose of avoiding false positive data due to genomic DNA contamination. 3. Synthesize first strand cDNAs using very small amount of total RNAs. 4. Normalize the quantities of cDNAs used in PCR. 5. Provide expression data (Gel pictures and digitized data).

Expertise Provided:
Our new technology SGMT, the second generation of microarray technology, is a completely revised microarray technology. Based on the chemical thermodynamics principles of the microarray hybridization reaction system, the experimental design, data collection, the data quality control and analysis are under totally different concepts and in different ways from that of the current microarray. We supply services of gene transcriptional profiling.

Expertise Provided:
Our company has a herbal preparation which has been researched and the result published in a peer reviewed journal, " African Journal of Biotechnology". The abstract is reproduced below:

"Jubi Formula® is a herbal preparation made from three medicinal herbs . It has been reported to have been successfully used in the treatment of anaemia in humans. A study was therefore carried out to determine the effect of the preparation on packed cell volume (PCV) and haemoglobin (Hb) concentrations in anaemic rabbits. The PCV and Hb concentrations of healthy rabbits infected with Trypanosoma brucei brucei were monitored for 49 days. T. b. brucei produced a significant reduction in PCV and Hb concentrations in all infected rabbits when compared with the controls (p<0.05). These hematological parameters were restored to normal levels in the anaemic rabbits by the herbal preparation. The anaemic rabbits not treated with the herbal preparation presented with a progressive decline in their PCV and Hb concentrations and majority of them died before the end of the study. Healthy rabbits that received daily doses of the herbal preparation showed gradual elevation in PCV and Hb concentrations which were maintained within normal range. Jubi Formula® can restore the PCV and Hb concentrations in anaemic conditions and is a potential substitute for blood transfusion. However, further studies are needed to investigate the potentials of the herbal preparation in reversing anaemia."

Key words: Anaemia, PCV, rabbits, haemoglobin, herbal preparation.

This product has been used in the traditional system to treat different types of cancer patients. We now want to collaborate with a research institute or laboratory to ascertain the relevance of the product for the treatment of cancer.

We need someone to guide us through the SBIR grant proposal process. We have a framework for a protocol, we have the pioneer product to be tested, we need an SBIR/STTR grant to proceed.

Expertise Provided:
We hold ANADA/NADA's on two different anthelmintics.

We want to combine the two and make claims for all indications of the two seperate anthelmintics in the combined anthelmintic product.

Expertise Provided:
We have pharmaceutical expertise and are looking for professionals in the areas of mycology and/or dermatology. In an effort to develop an effective treatment method for Tinea Manuum, Tinea Pedis, and Hyperhidrosis and Bromhidrosis Feet.

Expertise Provided:
The Laboratory of Nervous System Disorders (LNSD) of the Wadsworth Center, led by Dr. Jonathan R.Wolpaw has developed a new generation of brain-computer interfaces (BCI) that can provide both communication and control functions to those who have lost muscle control. By recording brain waves from the scalp and then decoding them, this radically new system allows people to move a computer cursor up and down and left and right, to spell words, and even to control a robotic arm [1]. The Wadsworth BCI system is a completely new technology and a major advance over conventional augmentative communication methods, which depend on muscle control and thus cannot be used by severely paralyzed people. The system is ideal for patients with Amyotrophic lateral sclerosis (ALS) and Athetoid cerebral palsy.

Expertise Provided:
An integrated EMR-PMS-eDM which is capable of connecting to the patients via POTS and connect to the medical professionals via Internet.

The eDM services are offered either in the ASP mode or in the dedicated server mode located at the rural hospital but managed by HealthHighway.

Expertise Provided:
Knowledgeable on the geometry of the human ear canal and patented disposables that improve the direct ear canal interface of electronic devices which create, control or measure sound in the ear canal. Experience with SBIR programs.

Substantial know-how in high tech foams for noise reduction and human ear contact

Expertise Provided:
• e-Business o N-tier Architecture (Client/Server with Middleware and Data Base) o Web Application/Development o WAP Application (Mobile computing) o Data Mining o Component Model o Load-Balancing and Fault-Tolerant Computing o Security, DRM (Data Rights Management) o BPM (Business Project Management) and its tool o Web Service

• Parallel and Distributed Computing o Static Analysis in Java/Object-Oriented Language for Parallel/Distributed Computing o Parallel Algorithm and High-Performance Computing in Image Detection, 2D/3D Graphics Application, Collaborative Work o Parallel/Distributed Computing in Java (J2EE) /Object-Oriented Language o Cluster Computing

• Network Communications o Load Sharing on BGP Mechanism of Multihoming in IPv6

• Programming Language (Java, Dom, SAX, XML, J2EE, JSP, Servlet, DB, Oracle, C++, {C#, J#, Visual Basic} .NET, Visual Basic 6, XML (VoiceXML, WML) - C/C++ (MPI, socket, OpenGL. .NET etc.), JAVA (applet, servlet, jsp, JavaBean, EJB, RMI, socket, JDK-1.3 2D/3D graphics, JAI, JDBC, JINI, JNI, security etc.), JavaCC (Java Compiler Compiler), JavaScript, LISP, SQL, HTML, XML (WML, VoiceXML), VRML, tcl/tk, Motif, SISAL, UML, Visual Basic 6.0, Visual Basic 6 and .NET, Perl.

Expertise Provided:
Epidemiologic design and statistical analysis, survey methods, health education, training tools, infectious dseases, program evaluation, minority health, technical assistance workshops.

Expertise Provided:
We have an inexpensive and rapid process for the secure transfer of video medical data over the Internet. We specialize in echocardiography in rural areas, but can transfer other video information as well.

Expertise Provided:
We have developed several programs using intelligent computational strategies to process unstructured data (including text, HTML, maps, pictures, video, audio, and others) and integrate such data with structured data sets in various content domains. We have a powerful language for analyzing the combined data, checking for data integrity, interacing with other applications, and report generation. We would like to collaborate on SBIR/STTR projects applying these technologies to particular substantive domains.

Expertise Provided:
* Robotic systems as to test integrative models of behavior, i.e. biorobots, biomorphic robots. * Distributed Sensor/Actuator Systems and Data logging * Computational Neuro-modeling *Custom VLSI chip design for low power applications including visual processing and data sampling *see expertise at http://www.iguana-robotics.com/services.html

Expertise Provided:
Digital and color image processing, image understanding, algorithms development, scientific and statistical analysis, imaging sciences, software and hardware development, testing, optics design, instrumentation, designing and conducting experiments, statistical analysis.

Expertise Provided:
Immnodiagnostic assay development and manufacturing including both rapid and ELISA assays. Experienced in infectious diseases and cancer, and in successful SBIR solicitations. We have successfully brought products through the FDA.

Expertise Provided:
IIPI develops custom solutions using mobile handheld and wearable computers. We provide expertise in human factors, interface design, training, and technical implementation. We have developed wireless solutions for a variety of uses including data delivery tools for those with disabilities and the aging, real-time tracking of patient location, data filtering, and maps. IIPI has extensive research and development experience with cutting edge mobile computing . http://www.informationinplace.com

Expertise Provided:
Our expertise is in data communications, networking, security, web-based applications, web services, and distributed systems integration. We are a committed technology partner and collaborator, with extensive R&D experience. Our staff members have received over 20 SBIR grants to date, resulting in a variety of operational systems, commercial products and services.

Our passion is to advance healthcare through appropriate use of health information technology to allow providers and researchers to share electronic health data in a timely, secure, and reliable manner.

Medical professionals:

1. Engaged in pulmonary function studies 2. Requiring hydrogen sensor in their research 3. Requiring optical sensors for dental applications 4. Requiring enhancement in Kidney dialysis machines 5. Engaged in environmental studies requiring screening/diagnostic tools

Expertise Provided:
Expertise Provided:

Optochemical sensors for diagnostic and monitoring applications

Expertise Provided:
Regulatory and clinical trials strategic planning; Literature reviews; SWOT analysis of alternate therapies; Hazard analysis; FDA and IRB submissions. http://www.innoventura.com

Expertise Provided:
Self-learning, task oriented software and experience with a collection of ambulation assistive devices including: New actuator with a power-to-weight ratio 185% greater than previously available in electro-actuators. New interface for those with tetraplegia allowing the patient to run computers, design graphics and direct the assistive devices above. Orthosis and Prosthesis controlling software with extensive self-leaning task and recapitulated task applications.

Expertise Provided:
Information Technology Network, System, Database, Software http://www.inovanetworks.com

Expertise Provided:
High level working knowledge of PET-based imaging trials, for Pre-clinical and Clinical studies. Expertise in developing multisite PET centers for single study/multi-site capability. Expertise in processing and analysis tools for evaluating efficacy of CNS therapies. VAR and Integrator of a hybrid HPC cluster solution utilizing PowerPC Linux.

Expertise Provided:
Small Medical device company with expertise in manufacturing of coronary and Peripheral stents. Company has some expertise in coatings technology and is seeking pharmaceutical company with anti-imflamatory, anti-immune or other related drugs to research and develop drug eluting stent.

Expertise Provided:
InsituTec develops innovative precision in-process solutions for the life science and precision industries. We provide self-contained computer automated hardware control systems which include 18 bit DSP hardware interfaces, multi-axis nanoscale motion control devices, precision displacement sensing and contact based force probes. We have a multidisciplinary research group skilled in the custom design of hardware interfacing and all aspects of flexure mechanisms and sensor design. Based on assessment of your needs we can design a complete system's solution. Using advanced modeling and previously verified analysis tools, dynamic solid models and performance specification can be determined prior to manufacturing. Once finalized the complete system can be manufactured, assembled, and commissioned by our experts.

Expertise Provided:
ITD specializes in both developing and exploiting innovative imaging technologies to extract desired information. Our organization's accomplishments include developing a suite of hyperspectral sensors that cover the Ultra-Violet, the Visible Near-Infrared, and the Short Wave Infra-Red portions of the spectrum, respectively. In fact, ITD's Portable Hyperspectral Imaging System was inducted into the Space Technology Hall of Fame(tm) in 2005. In addition, ITD has developed several patents from its intellectual property. Our research projects, both past and present, cover several application areas including public health (e.g. wound care, skin cancer detection, and optomology), agriculture, forestry, and forensics. ITD has a 21 year proven track record for converting its applied research results into commercial products or services. Our hyperspectral sensors were recently spun-off to Lextel Intelligence Systems. InTime, Inc., another ITD spin-off, services our nation's farmers with real-time prescription maps for applying crop chemicals. Our website's address is www.iftd.org.

Expertise Provided:
MEMS Foundry Services: ISSYS' services range from single-step processing to prototyping to qualified second source to full manufacturing to technical consulting. Please contact us for more information about how we can help you produce your medical device or other life science product.

Single-step processing Deep Reactive Ion Etching Dicing Anodic/Electrostatic Bonding Silicon Direct Fusion Bonding Screen Printing & Glass Frit Bonding Shadow Mask Photolithography Metalization KOH Etching EDP Etching Wet Processes Wyko Surface Profiler Thermal Oxidation Low Pressure Chemical Vapor Deposition, LCPVD Nanoscope Scanning Electron Microscope (SEM) http://www.mems-issys.com/html/memsfabric.html

Expertise Provided:
We have tons of empiricle evidence. We have the professionals and equipment necessary to do the research and will get the suggested number of clients as well as administer the therapy and keep the records you deem necessary to be able be do an acceptable double blind study for your peer review.

Expertise Provided:
We have developed and prototyped a new propulsion system for the manual wheelchair. We believe this will reduce chronic shoulder and wrist injuries as well as being more ergonomic (works both pectoral and back muscles evenly). In addition, automatic gearing systems have been designed to climb hills and negotiate rough terrain. This manual system will reduce muscle atorphy and can be prescribed for a spectrum of chair users.

Expertise Provided:
We have up to 30 out patient beds for overnight stays and also have research staff in 7 hospitals in the Salt Lake City, Utah area. We have over 20 years of research experience. We have a large database of patients to draw from to participate as a site. We also have experience in monitoring, data management, statistics and medical writing.

Expertise Provided:
As a result of JPL's unique position as the only Federally Funded Research and Development Center within NASA and managed by the non-profit institute of Caltech, JPL is encouraged to partner with small business via the STTR process to support innovative technology transfer between NASA and Industry. JPL's expertise in R&D for Communications and Navigation, Robotics and Autonomous operations, Active sensors and Instrumentation, Bio/NanoTechnology, and Advanced modeling, simulation and visualization have application not only in space but also in areas of bio-medical application. STTR partners have successfully worked with JPL to transfer robotics technology to the surgical theatre; sensors technologies to support cancer screening, spore detection, and patient monitor; communications technology for EMV and in-the-field triage; and scientific research into technologies for vision and mobility impaired patients. These technologies, some of which are on the market, in clinical trial or recently published will also be used by NASA in its manned and robotic missions. By partnering with JPL, small businesses can increase their likelihood of success both in the STTR process and in the marketplace and JPL can meet its goals for research and innovative technology transfer.

-exercise testing both laboratory and field. -developing weight loss programs and obesity prevention programs -measuring physical activities -prescribing exercise programs for healthy and diseased populations -working with minority groups -diabetes and cardiovascular disease management

Expertise Provided:
Kirby Wayne Beard Technologies, LLC is a development stage company engaged in technology development, consulting and applied engineering in the fields of process, chemical and materials engineering. KWB Technologies has significant intellectual property in the areas of polymer processing, composite materials, electrochemical technology, medical devices and processing of tissue and other biological components.

Design and execute in vivo study to evaluate new dermal filler formulations of sensitization and compatibility with soft tissues.

Expertise Provided:
We develop drug formulations in oral, parenteral, topical and transmucosal dosage forms. We specialize in intravenous delivery of insoluble and/or vein irritating drug substances, controlled release oral and injectable formulations, and oral bioavailability enhencement for insoluble drugs or compounds that subject to the first pass effect. We produce small batches of oral dosage form (tablets, capsules, solution, suspension and emulsion), IV formulations (solution, emulsion, liposomes), topical preparation (cream, ointment, gel) etc. For details, see www.latitudepharma.com

Expertise Provided:
Master Shover has 28 years of ongoing training and has been teaching for 25 years. She has several qualified instructors under her that enjoy working with dis-advantage indiduals that may benefit from training and building new skills.

Expertise Provided:
Leap of Faith Technologies specializes in the design and development of health information technology, creating theory-based interventions that have a positive influence on health behavior. We are a committed technology partner and collaborator, and add strength and value to research and development teams. We have considerable experience in needs assessment, application design, and development, and we deliver projects on time and on budget. We have received eleven SBIR Grants, which have enabled the development of new technologies for health communication. We have also been selected by the U.S. Small Business Administration for its Tibbetts Award, which recognizes the technological innovation, economic impact, and business achievements of firms involved in the SBIR program. See our work at: http://www.leapoffaith.com

Expertise Provided:
genetics, radiology, computer programming, business information systems, clinical support, basic database schemas and graphic design

Expertise Provided:
We drill calibrated micro holes less than 1 micron and larger.

Our capability is close tolerance microscopic hole drilling to a specific flow rate for gases, liquids, particles, x-rays and neutrons. Applications include flow and filtering of molecules, proteins, chemicals or other biological/chemical substances.

Expertise Provided:
Lice Source Services, is a clinic exclusively for the removal and treatment of head lice. This is a research center that has worked with pharmaceuticals and is now interested in applying for SBIR grant to research the possibilities of using a device for the removal of live head lice and nits. We have the population and "hands on" skill employees.

Expertise Provided:
Multi-disciplinary scientist and clinician, with emphasis on behavioral medicines. Have directed collaboration of experts in a broad range of disciplines regarding R&D dedicated to contagion control of infectious diseases. Have designed and patented globally-adaptable, affordable products and methods to educate, promote and provoke sustained positive changes in hand hygiene habits. "The only reliable means of preventing the spread of infectious diseases is frequent hand cleansing." (CDC). Safe hand hygiene in a disease prevention/wellness model is only viable means promote wide-spread, affordable, sustained changes in hand hygiene habits and prevent anticipated globally pandemics.

Expertise Provided:
List Labs has extensive experience in the production of both recombinant and native proteins, LPS and plasmid DNA. Capabilities include large to small scale fermentation and purification using traditional chromatography, precipitation and filtration as well as HPLC. Interested in assay development, toxin detection, FRET peptides. Experience with GLP and cGMP manufacturing.

List Labs is approved by the CDC to transfer and work with select agents. Manufactures research grade anthrax PA, LF and EF, botulinum, cholera, pertussis, tetanus and diphtheria toxins and staphylcoccal enterotoxin B, SEB. Subunits, fragments, toxoids and conjugates also available. A list of current products may be viewed at http://www.listlabs.com.

Expertise Provided:
LNK Corporation Inc. has developed an innovative approach and tools for course authoring and automated adaptive web-based and standalone delivery. Instruction, testing, assessment and remediation, are personalized dynamically "on the fly" during the learning process. We seek collaborators who can complement us with Subject Matter Expertise and content development.

Expertise Provided:
Know-how on synthesis of novel nanostructures of inorganic, hybrid (organic-inorganic), organic, and biological films, capsules and particles.

Expertise Provided:
Optical lens design and lens system design and analyses. Laser design and analyses.

Expertise Provided:
We create pre-clinical degenerative disease models that facilitate genetic and pharmacological insights into the regulation of adult stem cell populations. Any degenerative condition that results in the loss of specific cell or tissue types can be modeled with this system, thus, necessitating that partnerships be sought to investigate opportunities outside our immediate areas of expertise. Luminomics’ unique disease modeling technology enables, high-throughout, in vivo, assays for defining: 1) genes that regulate, and 2) drugs that stimulate, cellular regeneration.

Expertise Provided:
Lytron designs and manufactures liquid cooling and liquid temperature management components and integrated systems for several markets including the medical device industry. Lytron is an engineering and manufacturing-driven company. Our engineers have expertise in heat transfer, fluid dynamics, material analysis, and refrigeration. Our 58,000 sq.ft. factory can build prototypes as well as production quantities.

For more information see our web site, http://www.lytron.com.

Expertise Provided:
Magellan BioScience offers natural product discovery, fractionation, extraction and scale-up services. We specialize in marine microbial and microbial genomics for the discovery of novel chemical entities.

Expertise Provided:
Imaging, Optical MEMS, Photnics devices, High density high speed Photonics

Expertise Provided:
We are a team of medical doctors who will be filing a grant for production of mems medical devices. We have an expert electrical engineer with strong background in MEMS, are we are looking to supplement his work with a material engineer.

Expertise Provided:
In search of opportunity to collaborate with partner on a SBIR/STTR projects. Maxwell TSC provides a number of services including project management, program management, requirements analysis, software modeling, software development, technical documentation and process training with RUP, UML and CMMI. Consultants have PMP, Sun and IBM Rational RUP certifications.

Expertise Provided:
Clinical medicine, psychiatry, public health, public mental health, logic programming, object-oriented multi-tier software modeling and engineering, Java, Delphi, C#, automated indexing of digital recording, assessment, social networks. See our web site (http://www.mdlogix.com) for a list of specific SBIR projects and abstracts.

Expertise Provided:
Our current research interest is the use of animal models in orthoapedic and/or surgical research. We will design the animal protocol, perform the experiemnts, and evaluate the results by using mainly mechaical testing and histology. Common research sub areas include bone grafts and bone substitutes, bone and cartilage tissue engineering, therapeutic embolization, implant infection, internal fixation in osteoporotic bone, and body wall repair.

Expertise Provided:
MedSignals is a computerized, communicating pillbox that time-stamps each lid opening, poses questions verbally and permits real-time responses on the device, and uploads data daily to server. See MedSignals.com for applicability to research data collection.

Expertise Provided:
Medsys Technologies Inc has already secured exclusive licenses to a number of computer software programs for clinical use applications. One is targeted for use in magnetic resonance angiography vessel segmentation (i.e blood vessel image depiction, data recording and analysis) and one is for clinical patients records management,clinical reseach and data data reporting use. (For more expertise and product information please visit us at http://www.medsystechnologies.com)

Expertise Provided:
Mechanical, engineering, product testing, designing, opto-electronics, materials, robotics, fluorescence, sample preparation, instrumental analysis and microscopy, software and code. Excellent proposal writers with post Ph D experience in the fields of diagnostics, robotics, unmanned vehicles and autonomous systems, sensors, analytical instruments, metallurgy and materials, and manufacturing technology.

Website: http://www.meic.com/

Expertise Provided:
Melange Information Services, Inc provides management consulting expertise in the following areas:workforce development, change management, cultural competence training, staff development, program evaluation, health/behavioral health system design services to profit and non-profit organizations.

Expertise Provided:
MTI has a technology to generate monochromatic parallel x-ray. The technology is based on x-ray telescopes used by NASA for their space missions.

Expertise Provided:
Design of a custom MEMS based on the company proprietary innovative molecular electronic transducers (MET) technology. The angular 5 mm size MET-MEMS accelerometer with the sensitivity of 1-3.10-5 rad/sec2 /Hz1\2, and of similar size linear accelerometer with the sensitivity of 2-5.10-7m/sec2 /Hz1\2, both in the frequency range from DC up to 20 kHz with dynamic range of 120 dB and a high bias stability were designed. The set of the parameters can be optimized in a wide range in order to fit the partner application requirements and to provide the best performance for the system.

Expertise Provided:
Experienced pediatrician who ran a University-based metabolic center covering 5 different States. Extensive experience in diagnosis, treatment and research into Inborn Errors of Metabolism.

Expertise Provided:
Operations Research Analysis

Expertise Provided:
Clinical expertise in medicine and population health management. Expertise in fitness/kinesiology and nutrition. Management experience in medical and fitness facility operations. Protocols in wellness, disease management and weight loss management.

Expertise Provided:
Developing interactive, multimedia training/learning applications for a wide range of government and corporate clients. We have extensive experience in developing multilingual, video-based CD-ROM and DVD programs, utilizing proven learning theories and user needs analysis. Visit us on the web at http://www.mwmm.com

Expertise Provided:
siRNA and antisense oligonucleotides. We provide sequence design for both siRNA and antisense oligonucleotides for gene/protein function studies. We use our proprietary sequence design systems to design specific, active siRNA or antisense, depending on your needs.

Expertise Provided:
Develop neuroscience, science, and mental health related educational software for consumer and education markets. (K-12) Recipient of several Phase I and Phase II SBIR grants. We have a team of talented and energetic artists, writers, computer game designers, and programmers.

Expertise Provided:
1. Fabrication of novel hydroxyapatite microspheres with a nano structural surface morphology, based on US patent 6,358,531. Such materials could (1) deliver long term doses of chemotherapeutic drugs, or (2) be used for protein adsorption for cancer detection. 2. Fabrication of bioactive glass fibers for tissue engineering and resorbable polymer-matrix reinforcement.

Expertise Provided:
MVS Solutions is available to provide expertise in two main areas: (1) Chemistry Development; and, (2) Medical Device Development. Visit our website at http://www.mvssolutions.com/ for additional information and additional capabilities.

Expertise Provided:
Mycosynthetix, established in 2001, owns one of the most extensive fungal collections anywhere and has used these organisms as a proven source for new medicinal and agricultural products. Out database contains information on our unique 55,000 distinct fungal isolates including a number with known medicinal and agricultural bioactivity and those with identfied metabolites. We can provide fungal samples for random screening, samples with known activities, and extracts containing known, but frequently commercially unavailable, fungal metabolites. The majority of our fungi were isolated from plant material and have applications in the conversion of biomass into commodity chemicals, e.g., ethanol. Mycosynthetix routinely optimizes microbial fermentations for metabolite production and biotransformations. For more information see our website; http://www.mycosynthetix.com/

Expertise Provided:
We are able to provide clinical experience and consultation in the area of behavioral interventions for individuals with Alzheimer's disease. We provide experience in the testing and validation of new behavioral interventions.As experienced principal investigators, we can build instrumentation, design test protocols, and reduce data to knowlege. We also have expertise in research development, curriculum/outline design, human factors, training, multimedia design, interface design, and blended learnng techniques.

Expertise Provided:
NanoCraft, Inc. products can be applied to fuel cells, biosenors, composites, catalysts, obscurants, electrical conductivity, thermal conductivity and many more emerging areas with SBIR/STTR opportunities.

Expertise Provided:
Naturel Extracts Inc. has developed and patented a new method of extracting active principle from plants. This method is a low temperature extraction so the volatiles are retained. The process captures all the available actives. In most cases our finished product is an oil with long shelf life and is easily encapsulated in gel caps for convienent delivery. Our desire is to concentrate on botanicals that will work to stimulate the auto immune system. Currently we have promising results for plants that treat the Herpes Simplex Virus.

Expertise Provided:
NeoClone offers a patented method for rapid, affordable, high throughput development of exceptional quality murine monoclonal antibodies. The company is expanding its process to other species, such as rabbit mAbs and human mAbs. The Company also offers Softag, a gentle immunoaffinity chromatography purificaiton system, that enables non-destructive elution of the protein. See http://neoclone.com/

Expertise Provided:
Expertise in disease modelling, validation and screening of bioactive molecules in animal models of neurodegeneration.

Expertise Provided:
Medical Device Field

Expertise Provided:
NexTech Research and Design is a team of engineers and scientists with research and design expertise in diagnostic and therapeutic medical product development. Our team has created and implemented new technologies and has designed them into a variety of products, taking them through clinical trials, 510K submissions and into production. NexTech Research and Design has a created several cardiac related products each requiring software, electrical, mechanical and algorithm engineering expertise.

Expertise Provided:
A related experience and expertise of ours is in the use and development of workstations for presenting healthcare information to users, aquiring sturctured data (making use of controlled lexicons) from users, and mining this information to support clinical, research, educational, administrative and management aspects of healthcare entities.

Expertise Provided:
Automate and mobilize data collection from patient, caregiver and provider using integrated hardware and software technologies including audio, data, video messaging and conferencing. Focus on simplifying homecare applications and patient interface using computing and internet technologies while integrating/connecting third parties such patient education, pharmacy and other stake holders.

Expertise Provided:
Plastic surface modification for covalent attachment of biomolecules, assay development, 3-D nanostructure design and construction, patenting and grant writing skills.

Expertise Provided:
Collaborator brings extensive backgound in analog and RF instrumentation, in extracting low-level signals from noise, and in bringing commercial electronics products to market. Technical background includes solid state electronics and biomedical engineering at the Ph.D. level. Also has extensive experience with agricultural needs and constraints.

Expertise Provided:
In search of opportunity to collaborate with small business on an SBIR/STTR Project. I have expertise in immunodermatology with emphasis on the roles of dendritic cells and cytokines in cutaneous immune respones.

Expertise Provided:
Home health care in patients' homes.

Expertise Provided:
Ultra-precision manufacturing of any material for medical and other applications (instruments, implants, prosthetics, etc.) to tolerances of <5 nanometers. We are a small engineering services company that creates tooling and processes for the above.

Expertise Provided:
One Source provides accurate, on-time, and on-budget services for every aspect of the product development cycle. The following services are provided: product design/development, rapid prototyping (SLA,SLS), sheet metal fabrication, machining, injection molding, stamping, tooling, finishing, PCBs, assembly, welding and keypads. http://www.1sourcereps.com

Expertise Provided:
1. Growth of bacterial cultures. 2. Chromatographic purification 3. ELISA assays 4. Microplate assays of bacterial growth 5. Biosensor measurements of biomolecular interactions down to zeptomol levels.

2) dental company who would like to partner with scientists to develop and validate a new chairside test for dental caries

Expertise Provided:
Expertise provided by university investigator:

1) isolated new beta-adrenergic transcriptional repressor that can serve as a subtype-specific substitute for beta-blockers; proposal and potential as a new anti-hypertensive agent.

2) experience concerning rapid analysis of dental caries

Expertise Provided:
We conduct custom synthesis of small molecule organic compounds of various types, including nucleosides and carbanucleosides. We are also involved in new drug discovery for cancer treatment and cancer prevention, and for anti-inflamation.

For additional information about our services, please contact us at sales@orgsynlab.com.

Expertise Provided:
OrgSyn Laboratory, Inc. is a start-up contract process research and development company with a scaleup capabilitiy. The company offers process scale-up upto 2.0 Kg GLP material for research and toxicology studies. In next six months the company will be fully cGMP for phase I & II clinical material production. The company has a successfully synthesized and delivered >75 compounds to several biotech and biopharmaceuticals in USA in last two years and currently working on a five year contract funded by NIH. The company is staffed with highly experienced process chemists with a combined experience of over 100 years in major pahramceutical firms in USA.

1. Endometriosis 2. Psoriasis 3. Osteoporosis

Expertise Provided:
2-methoxyestradiol analog drugs to treat diseases of neovascularization

Expertise Provided:
PC Exer-Learning technology platform attached to cardiovascular exercise equipment, generating detailed 3D virtual exercise experiences, biofeedback, and continuous tracking and reporting of user workouts, heartrate, and health variables in support of physiological, cognitive, and behavioral research related to CV exercise. See http://www.Pantometrics.com.

Expertise Provided:
Assay development Cell culture Robotic system for high throughput screening PCR, and Other molecular biological techniques.

Expertise Provided:
In search of opportunity to collaborate with small business on an SBIR/STTR Project the program director has 10 years of working with people that have experienced Spinal Cord and Brain Injury helping them with behavioral, psychological, vocational, and communication goals.

I am looking for a collaborator who could test such a biological activity under secracy agreement.

We are interested in working with other labs to enhance development of intellectual property, as provided by SBIR and STTR grants in the path to commercialization.

Expertise Provided:
PharmOptima is a newly formed company made up of a group of former industrial (Pharmacia) Discovery Research scientists (http://www.pharmoptima.com).

Our expertise includes extensive experience in assay design, including enzymes and receptors, as well as whole cell assays from bacterial to mammalian. Our expertise includes developing assays for high throughput screening (HTS) and several of our members have extensive, direct experience carrying out HTS in a wide variety of assays and detection systems, including substantial experience in therapeutic areas including CNS, oncology, cardiovascular, metabolic diseases, inflammation, and infectious diseases including viral, bacterial and fungal diseases. The expertise encompasses an extensive array of assay formats, such as radiometric assays utilizing filtration, RIA, ELISA, and scintillation proximity; fluorescent based assays including intensity, polarization, time-resolved, fluorescence correlation spectroscopy (FCS), polarization/anisotropy (FP), and Forster resonance energy transfer (FRET); absorbance/colorimetric; and luminescent. Following screening, staff members are experienced in turning hits into leads, including secondary assay design and implementation, determining biochemical or cellular mechanism of action, up to and including animal testing for delivery, efficacy and potency.

We are affiliated with a public HTS center located in the same building that will allow us to provide HTS in addition to assay development and follow-up services to HTS.

http://www.photon-industries.com

* Behavioral interventions for individuals with Alzheimer's Disease, particularly therapies based on video, photos, slideshows, and music.

* Focus groups or user tests to validate new behavioral interventions. Participation in free programs to evaluate intervention efficacy.

We are also interested to contact:

* Professors and academic researchers in the Behavioral Science area related to individuals who are older, have Alzheimer's Disease or related dementia, especially those interested in reminiscence therapy based on photos, slideshows, and video.

* Groups who provide care to individuals older, have Alzheimer's Disease or related dementia.

Expertise Provided:
* Electronic technology: systems, photo software, and web services for digital video and photo slideshows with songs.

* New interventions based on personal digital photo album, slideshows, video, and music.

Please see http://www.photozig.com or http://www.photozig.com/_RD/healthcare.htm

* Computer programs for individuals with cognitive disabilities. On-going research project to develop new concepts and methods to improve quality of life of such individuals.

* Computer and advanced digital photo album system. Software to organize, enhance, email, and share digital photos and slideshows.

Expertise Provided:
MEMS, specialized probe for AFM/SPM, nanotech measurement systems

Expertise Provided:
Plasma Dynamics is devoted exclusively to the plasma processing of materials by reactive ion etching (RIE) and plasma enhanced chemical vapor deposition (PECVD). The company maintains a state-of-the-art laboratory with etching and deposition tools that include Trion loadlocked and inductively coupled plasma (ICP) equipped Minilock II RIE and Orion II PECVD systems as well as optical microscopes, an Amray 3600 SEM, and Dektak surface profiling equipment for pre/post examination of etched and deposited samples. These tools are key to the development of MEMS based biosenors. Plasma Dynamics services include R&D, process development, as well as low level production.

Expertise Provided:
We provide a variety of chemical synthesis services for life science researchers. We perform contract research, process development, and custom synthesis of the organic molecules. PolyOrg is well equipped to deliver products on a gram to Multi-kilogram scale. We also have full analytical capabilities to support complex organic chemistry projects.

Expertise Provided:
Application development using handheld, wireless technology in areas of clinical trial and patient outcome and other necessary data collection. Extensive experience in research and development.

Thus, I need to have research partner who is knowledible with this area of study. I have published about 10 papers related to this project. I am specfically looking for diabetologist who will work together with me for the final FDA approval of CHP plus zinc for health claims.

Expertise Provided:
Diabetologist or engaged in diabetes related research, or any other specilaites to obtain NIH fund and carry out the research as a priciapl investigator.

Expertise Provided:
Monoclonal and polyclonal antibody and assay development, molecular biology and protein biochemistry, manufacturing and quality assurance, extensive successful product development and launch experience.

Expertise Provided:
We are a small research and development company with many years of experience in acoustics and vibration, including infrasonics and ultrasonics and strong university ties. Technologies we are seeking to develop are: 1. An ultrasonic pulsed Doppler method for rapid non-invasive measurement of particle (down to 40 nm), micelle, cell and cell aggregate concentrations. 2. An ultrasonic method for non-contact through-wall stirring. 3. A patented vibration-enhanced membrane filtration system with high shear decoupled from cross flow. This has shown very high flux, prevention of concentration polarization and fouling, and efficient dead-end processing of highly fouling solutions.

Expertise Provided:
We have a publisher, project manager, linguist, and programmer and a tested prototype of a highly successful system and CD ROM. It should be a "staple" in everyone's pc worldwide.

Expertise Provided:
PROMETRIKA, LLC is a contract research organization offering complete biostatistical, clinical data management, SAS programming and medical writing services. PROMETRIKA, LLC was formed by key members of the drug development division at a mid-sized international pharmaceutical company with offices in the Boston area. As such, the team is a cohesive and synergistic group with a ten-year history of working together in the drug development arena and with a proven record that includes two new drug application (NDA) submissions approved by the FDA.

Expertise Provided:
Proteomic Research Services (PRS) is a full service provider of proteomic laboratory, training and consulting services with value-added solutions(http://www.prsproteomics.com). PRS is dedicated to providing high quality service in protein separations and biological mass spectrometry. The services provided include differential protein analysis and proteome mapping, R&D support for proteomic technology development, proteomic training and protein identification and characterization by mass spectrometry. The capabilities of PRS include sample preparation, depletion of abundant proteins from serum, chromatographic fractionation, free flow electrophoresis, solution phase IEF and protein microarray analysis.

Expertise Provided:
PyramidTech provides engineering services for the development of innovative ultra high-speed digital systems for image formation from optical, electro-optic (EO), infra-red (IR), acoustic, radar, and ladar sensors used in medical, space, and military applications. We specialize in the development of digital signal processing systems based on Xilinx high-end FPGAs and reconfigurable computers.

Expertise Provided:
Expertise provided: 17 years engineering experience, 15 years teaching experience 10 years specializing in science education developing hundreds of science lessons Published three books

Expertise Provided:
Micro-sized power electronics, integrated and miniaturized digital processing electronics, (end-tip) actuation mechanisms, wireless communication, electronics analog, digital and mixed circuit design & simulation, thin film sensors (strain, temp.), multifunction graphical visualization tools and USB specialty interface hardware.

Expertise Provided:
I am a 22 year veteran of clinical dentistry who has started a health care product design company - Quanotech. My lead product is a periodontal diagnostic system that is revolutionary and will change the way professionals diagnose periodontal disease.

Expertise Provided:
Manufacture, and develop intellectual property rights for, personal respiratory heat exchangers. These heat exchangers heat inhaled air for people in cold climates.

Expertise Provided:
I have invented a device that improves the hand and eye coordination for stroke survivors.

2) Bioremediation experts with field experience using natural attenuation and augmented biodegradation.

Expertise Provided:
1) Routine and research respirometric testing laboratory for biological and chemical matrices. http://www.respirtek.com/homeland.html

Expertise Provided:
Established in 2000, Ridgetop is a fabless semiconductor firm, and has designed precision signal conditioning and mixed-signal IC's and PCB's for critical measurement applications. http://www.Ridgetop-Group.com/index.htm

Expertise Provided:
Smart contrast media with data and preclinical data. Validation in animal models at Stanford University, MGH and NYPH

http://www.technimed.com

Expertise Provided:
RTP Consulting offers a broad range of expertise in research design and statistical analysis. Foci are in Compliance; Education/Training (theory, standards, teacher-, school-, district- level evaluation, testing, program feasibility, effectiveness); Instrument Construction (survey, questionnaire and test design and pilot testing); Quantitative and qualitative analyses; and data mining and extraction.

In addition, RTP does high quality web and print publication, editing, and presentations.

Expertise Provided:
SAGE Bio has experience in the development of prophylactic and therapeutic vaccines against infectious diseases. The company's particular area of expertise lies in the development of immunotherapeutics and vaccines for emergent and chronic pathogens.

Expertise Provided:
Samaritan Pharmaceuticals is a drug development company driven to commercialize its pipeline of innovative drugs. Samaritan, in collaboration with principal investigators at universities, is currently seeking partners in AIDS, Alzheimer's, Cancer and Cardiovascular disease.

Expertise Provided:
SciberQuest, Inc. specializes in providing advanced data mining solutions and simulation services to handle the most complex computational and data analysis facing the scientific world and industry. Moreover, we offer high performance and grid computing assistance. For more details please visit http://sciberquest.com.

Expertise Provided:
chloride ion sensing

Expertise Provided:
We are providers of scientific and clinical research services throughout Florida. Our CRA and CRC perform on-site evaluations of research facilities to ensure compliance with FDA and sponsors protocols.

email: info@sccds@verizon.net

Expertise Provided:
Senior Citizens Counseling & Delivery Service (SCCDS) is a 501 (c) (3) non-profit organization. SCCDS has provided services to Washington's elderly population for over 25 years. The central focus of all corporate sponsored programs are the needs of the low income elderly. Currently, SCCDS is "piloting" a collaborative health screening "on-site" medical clinic with area physicians at a medically certified Geriatric and Alzheimer's Adult Day Care Center. This effort is an attempt to reduce health disparity among the elderly and indigent poor. SCCDS is part of the United Way.

website: http://www.sccds.net/

Expertise Provided:
Integrated genomic and analysis of molecular variation for microbial targets. Design of targetable regions informed by host and microbe genomic analysis, phylogenetics, thermodynamic binding predictions and secondary target minimization.

Expertise Provided:
Specialty Scientific Equipment Manufacturers

SES Research has specialty equipment manufacturing and low cost proof of concept proto-typing at its foundation. The early success of SES Research in the Fullerene manufacturing business is due in large part to the novel concepts and exacting standards used to design and build the Fullerene production machines.

In 1990 only a hand full of scientist were aware of the existence of Fullerenes. The design of a new process for producing macro-scopic quantities of these Fullerenes led to a boom in the research of Fullerenes. SES Research took this new process, refined and optimized the components and manufactured one of the first fullerene production machines.

Expertise Provided:
Murine and human hybridoma and monoclonal antibody development services. Cell line and purification process development up to clinical production. Preclinical animal pharmacology services. http://www.sierrabiosource.com

Expertise Provided:
Training and supervising staff to facilatate fall prevention exercise program in their health care facility. Providing insight to health care workers as to how to motivate the elderly. See web site at http://www.geocities.com/benevolentballet.

Expertise Provided:
Psychology; behavioral medicine; infectious disease contagion control; behavior modification ;realistic patented system of implementing sustained changes in habits responsible for the spread of infectious diseases, whether natural or deliberate outbreak; medicinal herbology; public health; education; business management; recruiting; collaborative design and direction; patenting process; creative; brilliant; with incredibly commercializable product group and spin-off potential galore. This patented (two issued; two pending) system of contagion control is a multi-disciplinary project and of value to a variety of SBIR - friendly agencies in HHS, DOD, OSHA, EPA

Expertise Provided:
SIFT is interested in the research and design of advanced human - automation systems. Our expertise in the design and development of automated information collecting and analysing software systems has lead to successes in the elder-care, software engineering, and aviation domains. In addition, SIFT is pioneering human-machine interaction models to develop socially-aware avatars with whom computer users can interact for a variety of purposes such as situation reporting or training. Please see SIFT's website for company and staff profiles: http://www.sift.info

Expertise Provided:
Program and Policy Evaluation Studies, Application of Quantitative Methods, Survey Design and Validation, Experimental and Quasi-Experimental Designs, Epidemiological Studies, Blinded Randomized, Pharmacoeconomics, Cost Benefit Analysis

Expertise Provided:
Solulink can provide unique and expert chemical conjugation products and services for the conjugation of molecules to one another and to solid surfaces for bioassay, nanotechnology,microarray, diagnostic and therapeutics applications. Solulink has applied for and has been awarded SBIR grants previously.

For more information, please see: http://www.solutions-ies.com.

1. Topical/Transdermal drug delivery-passive delivery, iontophoresis or sonophoresis or use of nanoparticles. We have the capability to conduct in vitro and in-vivo studies in animals 2.Use of our novel nanoparticulate delivery systems for drug delivery solutions in various therapeutic areas. Industrial partners who are interested in commercializing our technology are also welcome.

Expertise Provided:
My lab is mainly focused on addressing drug 'deliverability' issues across skin and cellular membranes using nanotechnology. I have more than 10 years of research experience in the area of pharmaceutics and drug delivery. Our main focus is on topical/transdermal drug delivery and devloping nanoparticulate delivery systems. We use nanoparticles and physical methods such as iontophoresis and ultrasound waves to increase the permeation of drugs through skin both for topical and systemic drug delivery. The research performed in my lab are focused towards developing synthetic and natural nanoparticulate drug delivery platforms. We work on a variety of molecules including small molecules, proteins and oligonucleotides in various therapeutic areas such as cancer, vaccine delivery and cardiovascular diseases. Recently we have developed novel nanoparticles using a natural protein biopolymer and plan to patent the technology.

Expertise Provided:
SRI International has over 40 years of experience in the drug development business and has considerable experience in helping small businesses apply for and successfully complete grants under the NIH Small Business Innovative Research (SBIR) and Small Business Technology Transfer (STTR) programs.

SRI International Biosciences provides comprehensive discovery and development services to take your lead drug or biological from "idea to IND". These include target identification, lead discovery /optimization, vaccine development, efficacy models, toxicology, pharmacokinetics, metabolism, formulation, analytical chemistry, clinical trial material manufacturing, quality assurance, and IND preparation; all at one location.

Visit us at http://www.sri.com

Expertise Provided:
STAR Cryoelectronics (http://www.starcryo.com) designs, manufactures and markets magnetic sensors based on superconductors and related control electronics for a broad range of applications including biomagnetic imaging (MEG and MCG). The company also offers custom thin film foundry services.

Expertise Provided:
I am an accomplished entrepreneur who previously commercialized a SBIR sponsored Rapid Prototyping technology invented by me. Through two small companies that I run (http://www.cubictechnologies.com and http://www.stereoniks.com), I can offer expertise in Rapid Prototyping, Custom Automation, Product Development, and CAD design.

Expertise Provided:
SterlingTech provides software services for medical device companies. Services include: Full life cycle development and testing (software verification and software validation); Requirements capture; Risk planning and hazard identification; Providing guidance, artifacts and support for FDA/CE submissions; Architectural design; Software design; Implementation of code; Project management (Detailed and timely status updates and Accurate schedules). On premises hardware lab to support debugging of hardware interfaces. More information can be found at: www.sterlingtechsoftware.com.

Expertise Provided:
Structured Materials Industries, Inc. (www.structuredmaterials.com) offers expertise in advanced thin film materials. Applications include electronics, photonics, passivations, optical, photovoltaic, protective and so on. Our specialty is in developing enabling material processes and transfering the processes and tooling to our customers and collaborators for their applications.

SynApps applies a variety of IT technologies to procude sound technical solutions including J2EE, .NET, C++, Java, Oracle and SQL Server.

Expertise Provided:
We develop bioinformatics software and provide support based on data mining, pattern recognition, statistical methods and mathematical simulation methodologies.

The software can be used by biochemists and biologists in high throughtput data/image analysis, biochemical instruments calibration, biological systems mathematical modeling and simulation, with minimum math background.

The bioinformatics software can be used in gene, protein, metabolite profile analysis, sequence data analysis, cellular phenotype image analysis, and their integrated analysis.

Expertise Provided:
TechEn is a Full Service Electronic Product Design Center. TechEn specializes in mixed signal hardware design and embedded firmware DSP processing. In addition, TechEn provides prototype development and is an authorized FDA manufacturing site. Since 1982, TechEn has extensive experience developing embedded, real-time firmware/software for a wide range of applications and TechEn is an authrized third party consultant for Analog Devices, TI, ATMEL, Motorola and Microchip.

Expertise Provided:
Complete project lifecycle management or management of discreet project phases for wireless communications, data collection tools, and wireless software systems - including Phone, Handheld, and Tablet PC applications; data synchronization; data security; wireless transmission security; and wireless/wired communication methods. For more information: http://www.techgenii.com.

Expertise Provided:
TekMark Growth Partners is a leading technology, marketing and strategic management consulting firm looking to collaborate with small business on SBIR/STTR projects. We help technology and engineered product based companies grow through a variety of proven processes and programs focused on new business development, new product development, technology commercialization, channel management, technical research, competitive analysis and overall strategy development.

In addition to medical devices and life science related technologies, other market, product and focus areas include MEMs devices, semiconductors, nanotechnology, electro-optics, photonics, sensors, thin-film processing equipment, metrology systems, test & measurement, and other similar devices and equipment.

The development of the jtaste aversion approach is clearly multidisciplinary. I am in need of technical assistance regarding the following topics. 1) Clinical research collaborator to admister a clinical trial to demonstrate the efficacy of the approach. Ideally someone experienced in the field of sleep/bruxism research. 2) Orthodontist or someone similarly skilled in the field of dental appliances to consult on the development of the appliance to hold the capsules. 3) A doctor, dentist, or clinician who is qualified to comment on the safety of various substances delivered intraorally during sleep. (The quantity is quite small, approximately .5 ml)

Expertise Provided:
Licensed L.M.T. with 3 years of experience practicing Massage Therapy, Reflexology, Ashiatsu Oriental Bar Therapy, Holistic Therapies, Herbal Medicine, Alternative Medicine looking for opportunity to be involved in research on the benefits and effectiveness of massage therapy and reflexology for the treatment of headaches and other disorders. I have excellent documentation skills and experience with recording patient progress who have had significant reduction in # of headaches and other problems through regular massage and reflexology treatments that I have given and documented. Knowledge of anatomy/physiology

Specifically TiaLinx, Inc. is interested in Clinical expertise in the area of tissue interfaces and visual anatomic guidance (hardware and software system) to facilitate acquisition of medical images in desired anatomic view or image plane.

This technology can be applied to enhance systems intended for medical diagnosis, or to guide or direct therapeutic imaging.

Expertise Provided:
Design and implementation of ultra high frequency radio systems for active and passive imaging applications.

Interest in testing new material for medical intrauterine applications. To develop a new intrauterine device for human or animal use. To test for other uses of this material in relation to reproduction, cell and tissue compatibility etc.

The physician should be well established in the field of neonatalogy with some knowledge/interest in infant massage.

Expertise Provided:
Research, Web Design Development, Application / Related experience in the area of Mental Disorders as well as now defined as MR.DD

In addition to optical expertise, extensive chemistry, electronics and materials science capabilities are also abailable at TPL, http://www.tplinc.com. TPL is a small business with a good commercialization record.

Expertise Provided:
Epidemiologist, clinical trial site, screening and patient population access.

Expertise Provided:
We have the expertise to synthesize novel, efficient, non-toxic luminescent nanoparticles. These can be characterized with a wide range of materials analysis techniques and equipments. These include PL, TEM,SEM,FT IR, EDS, UV Visible, XRD etc. (all available in house.)

Expertise Provided:
We have discovered a class of novel derivatives of maltose and glucose which increase glucose disposal and lower blood glucose in diabetic animals by increasing liver and muscle glycogen synthesis.Compounds are active orally and serve as substrates for glycogen biosynthetic enzymes, thus priming glycogen synthesis in vivo. This discovery is the subject of an issued U.S.Patent 5,817,634.

Expertise Provided:
A novel type of nanoparticle that has both luminescent and magnetic properties was produced by flame-spray pyrolysis. These nanoparticles made of lanthanide oxides are promising fluorophores and serve as a new class of tags in biochemistry because of their large Stokes shift, sharp emission spectra, long lifetime and good photo-stability. These properties greatly reduce background signal-to-noise, vastly improving detection limits, increase sample stability, reduce sample volume requirements, facilitate quantitation and allow for new inexpensive "lab-on-a-chip" assay formats. The synthesis method offers low-cost, high-rate synthesis, allowing a wide range of biological applications of magnetic/fluorescent core/shell particles. The nanoparticles have been used to the visualize protein micropatterns. The fluorescent nanoparticle tag did not suffer any photobleaching during the observation, further demonstrating the suitability of Eu:Gd2O3 nanoparticles as fluorescent labels.

We have applied our magnetic/phosphor nanoparticles to a "lab-on-a-chip". The nanoparticles acted as antibody carriers; manipulation of the nanoparticles and separation was achieved with external electromagnets that also served to accelerate immuno-reactions by reducing detection time by a factor of about 10, while consuming very little reagent volume. Our assay is insensitive to the efficiency of separations or losses on walls allowing for improved quanititation. Multiplexed assays on the same nanophosphor substrate can be run by using multiple labels for the secondary antibodies, offering enhanced throughput.

The advances described above were made possible by grant number 5 P42 ES004699 from the National Institute of Environmental Health Sciences, NIEHS. The description of the above technology are solely the responsibility of the authors posting the information and do not necessarily represent the official views of the NIEHS, NIH.

Bidders for the license to use this technology to treat, diagnose or monitor human cancer immunotherapy or other threrapy forms are patented protected. Resources are required to conclude a phase 1/2 clininical trial to show additional safety and efficacy of Dendritic Cell [DC] immunotherapy in patients with advanced breast cancer and to then seek the marketing of this license to a large manufacturer capable of producing this vaccine and securing FDA approval should apply for a teaming relationship with us. This patented technology is well described in the peer reviewed cancer immunobiology literature. STTR/SBIR funding is need to complete clinical trials in all major forms of human advanced cancer.

Expertise Provided:
See above please! We are searching for a qualified, small business dedicatred to cancer immunotherapy, early detection and therapy monitoring to acquire a full license agreement covering the above technology. The DC vaccine therapy showing success in treating advanced human cancers is ready for seeking FDA approval.

Expertise Provided:
Animal Model, Molecular Biology

Expertise Provided:
VasoTech, Inc has developed a stent family for coronary artery disease. Currently the company has a patent-pending programmed drug eluting stent design and a drug formulation for restenosis.

Expertise Provided:
Our expertise is with laser and optical engineering and molecular physics and spectroscopy. We have several prototype technologies with potential biomedical applications, for example:

sub part per trillion sensing via a new technique with a world record demonstrated sensitivity orders of magnitude better than cavity ring down. Potential applications include breath analysis, hazardous chemical concentration quantification, trace analyte detection, etc...

Integrated optical technology to achieve the equivalent of mm scale mirror translation with no moving parts. Potential applications include FTIR spectrometers integrated with Lab-on-a-Chip microfluidics, optical coherence tomography, attenuated total reflectance (ATR) based bio-sensors, etc..

Expertise Provided:
Victor/Harder Productions, Inc. is a full-service health and medical communications company producing film, video, CD-ROM and web-based interactive content for business, education and broadcast. Our experience includes numerous educational video programs and curricula currently in national distribution, as well as recent broadcast productions for PBS, the Discovery Channel and others. We can be your STTR small business partner, or we can provide content development, video production/CD-ROM production and distribution services as a subcontractor.

Expertise Provided:
Video, DVD, Animation, Interactive CD-ROM production. Staff of scriptwriters, producers, shooters, editors and animators. Feature non-linear component edit suites. Also produce video for the web. Personnel with SBIR project experience as project/production managers, technical managers, production staff, etc. www.visionvideoinc.com 605-335-7791

Expertise Provided:
This new baking company is the outgrowth of the Vision's Sown Nutritional Anthropology Research Project that is seeking to discover whether ancient grains and indigenous medicinal botanicals incorporated into its experimental 'functional' and organic bakery products can lower cholesterol when incorporated into an overall heart smart diet. Our lead products have been lab tested and are able to make the FDA qualified health claim for nuts (almonds) and heart health. Additionally, the baked goods are low in saturated fat and sodium, high in fiber, contain essential mono & polyunsaturated fats predominantly and are cholesterol and trans fatty acid free. We are looking to have a diverse group of participants eat these baked goods exclusively over a period of time to monitor whether or not this unique dietary strategy can be successfully incorporated into a cholesterol lowering health plan.

Seeking Principle Investigator with expertise in dysphagia. Must have experience with epidemiological studies and prior NIH funding.

2. to generate pre-clinical data for a potent germicidal molecule for external use. Preliminary in-vitro data has already been generated.

Need collaboration in developing these two molecules.

Expertise Provided:
Have extensive experience in drug discovery and development for many years, both in pharmaceutical industries and FDA.

Expertise Provided:
Computer simulation expertise (finite element modeling, FEM or FEA) in the area of piezoelectrics, electrostatics (MEMS such as cMUTs) and ultrasound, for device analysis, medical imaging, and therapeutic/thermal applications such as focused ultrasound surgery (FUS or HIFU). Our software is developed in-house and highly adaptable for new applications, and support staff are experienced in a wide range of medical ultrasound issues.

Expertise Provided:
www.wickslifeline.com explains in greater detail how my dual purpose water pipe invention combats smoke as well as people`s inhalation of (a) the toxic smoke created in fires and (b) the noxious gases produced during a biological/chemical strike. The Wicks Lifeline Air System is built into the plumbing of fire resistant, compartmented structures. The pipes` conversion process automatically is triggered when the fire alarm sounds. Panicked, trapped victims only need to remember to shut the (restroom, bathroom, other room's) door. The prototype and demo units were built, tested, and validated at Stevens Institute of Technology, Hoboken, N.J. Building Officials and Code Administrators International, Chicago, IL also tested the Wicks Lifeline Air System and found it to be feasible (BOCA National Codes, Research Report #85-96). Numerous fire chiefs, fire marshals, and other fire industry pundits publicly endorse this product. For many reasons, the commercialization of the Wicks Lifeline Air System was held in abeyance. In 1998, though, I secured a revised patent on it. In November 2004, Stevens Institute of Technology encouraged us to seek SBIR/STTR funding since the War Against Terrorism makes this invention so timely!

Expertise Provided:
I am a Registered Respiratory Therapist with an interest in producing a product to help protect the airways of asthmatics, COPD'ers and other lung and heart patienst with trouble breathing in cold air.

I have a prototype product that has already been tested by the army and around the country. With further research and development, this product can help thousands of people with lung diseases.

Expertise Provided:
Section 8(a) certified company with extensive expertise in business management, training and education, and occupational and environmental health to collaborate on an SBIR/STTR project. Human resources include CPAs, CIH, MDs, PEs, MBAs.

Expertise Provided:
biochemistry, pharmacology

Expertise Provided:
YOUTHUSA develops and manages programs to support local capacity building to include communities of faith. We provide mobile outreach and technical assistance support to historically disadvantaged, rural and economically challenged Americans. We are particularly committed to the development of STTR programs at historically black colleges and universities (HBCU) and economic development in historically underutilized business zones (HUBZONES)

Expertise Provided:
Zerosum is a bioinformation technology startup (BioIT). We will provide the bionanoengineering, software engineering, integration with our biocenter computing technologies, and product prototype development expertise.

Expertise Provided:
Investigation and implementation of significant HW and SW improvements on a mature premium commercial ultrasound imaging system. We are focused on major advances in image resolution, Doppler performance and acoustic power delivery. We work from scientific and physical concepts through engineering realization and product release including getting FDA approval. We have a proven track record in collaborations with research universities.

Expertise Provided:
The focus of our studies at present is development of minimally invasive techniques for steroid hormones especially in saliva and blood spot. In this direction, we offer our facility, competitive expertise and support for design and conduct of innovative research. Details of our services can be found on our websites http://www.bloodspottest.com and http://www.salivatest.com

Expertise Provided:
Development and commercialization of patient-centered expert systems for remote management of chronic disease.