The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Stage II Prostate Cancer ¹

Added D'Amico et al. as reference 29 ².

Stage III Prostate Cancer ³

Added text ⁴ about those men in particular who do not have underlying moderate or severe comorbidities considering hormonal therapy in conjunction with radiation therapy (cited D'amico et al. as reference 5).

Added text ⁵ to include overall survival at 10 years and disease-specific mortality statistics (cited Pilepich et al. as reference 11 and Roach et al. as reference 12).

Added text ⁶ about the degree of effectiveness of intermittent versus continuous androgen suppression in stage III or stage IV prostate cancer patients and the lack of reliable data found in five randomized trials addressing this issue (cited Conti et al. as reference 38 and level of evidence 1iiA).

Stage IV Prostate Cancer ⁷

Added text ⁸ about the degree of effectiveness of intermittent versus continuous androgen suppression in stage III or stage IV prostate cancer patients and the lack of reliable data found in five randomized trials addressing this issue (cited Conti et al. as reference 28 and level of evidence 1iiA).

Recurrent Prostate Cancer ⁹

Added statistical text ¹⁰ about overall survival at 3 years (cited Berthold et al. as reference 37).