Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01)
http://grants1.nih.gov/grants/guide/rfa-files/RFA-GM-09-008.html


bullet   Purpose
 This RFA is for exceptionally innovative research on novel hypotheses or difficult problems, solutions to which would have an extremely high impact on biomedical or biobehavioral research that is germane to the mission of the National Library of Medicine. The RFA supports new projects, not continuation of projects that have already been initiated. It does not support pilot projects, i.e., projects of limited scope that are designed primarily to generate data that will enable the PI to seek other funding opportunities.

For the EUREKA program, NLM seeks innovative applications in the following two ‘discovery science’ areas:
  1. Integrated discovery mining for biology and medicine: employing two or more sources to generate a new and meaningful hypothesis in biomedical science, capable of being tested by bench or clinical research. One source must be full-text published biomedical literature; the other source should be either (1) a database storing primary data from basic biomedical research or (2) data drawn from the electronic health records used for routine clinical care or from the data accumulated for a clinical research project. The interface of an integrated discovery mining system should support easy use by the intended users (i.e., by biomedical researchers or clinicians). Mining techniques should involve minimal human intervention.

  2. Integrated hypothesis testing for biology and medicine: employing two or more sources to test rigorously in silico a new and meaningful scientific hypothesis in biomedicine, one which otherwise would require laboratory or clinical verification. One source must be full-text published biomedical literature; the other source should be either (1) a database storing primary data from basic biomedical research or (2) data drawn from the electronic health records used for routine clinical care or the from the data accumulated for a clinical research project.
Applicants should include a cover letter that requests assignment to NLM. In addition, applicants are strongly encouraged to discuss their proposed application with NLM staff contact before submitting a proposal. Only electronic applications are accepted. This one-time RFA has a single application deadline and expires October 29, 2008 unless reissued. No revisions or competing continuations will be accepted.

bullet   NLM Contact
 Dr. Valerie Florance, florancev@mail.nih.gov

bullet   Deadlines
 Deadline for Letter of Intent: September 29, 2008
Deadline for New Applications: October 28, 2008

Last reviewed: 19 August 2008
Last updated: 19 August 2008
First published: 19 August 2008
Metadata| Permanence level: Permanence Not Guaranteed