Skip to Content
Predictive Multiscale Models of the Physiome in Health and Disease (R01) (PAR-08-023)
http://grants.nih.gov/grants/guide/pa-files/PAR-08-023.html


bullet   Purpose
 The goal of this funding opportunity announcement (FOA) is to move the field of biomedical computational modeling forward through the development of more realistic and predictive models of health and disease. NIH recognizes the need for sophisticated, predictive, computational models of development and disease that encompass multiple biological scales. These models may be designed to uncover biological mechanisms or to make predictions about clinical outcome and may draw on a variety of data sources including relevant clinical data. Ultimately the models and the information derived from their use will enable researchers and clinicians to better understand, prevent, diagnose and treat the diseases or aberrations in normal development. Specifically this FOA solicits the development of predictive multiscale models of health and disease states that must include higher scales of the physiome. The specific objectives are to develop multiscale models that are physiologically mechanistic and biomedically relevant, to bring together modeling and biomedical expertise to collaborate on building models, to validate and test models with standard datasets, and to develop models that can be explicitly shared with other modelers.

The National Library of Medicine (NLM) is interested in new or enhanced predictive models of health and disease that incorporate cell, tissue, organ function, and/or physiological processes. We are also interested in models of health and disease that are relevant to public health and population health studies, such as those which incorporate behavioral, cultural or environmental factors.

bullet   NLM Contact
 Dr. Jane Ye, yej@mail.nih.gov

bullet   Deadlines
 January 14, 2008, May 14, 2008, September 15, 2008, January 14, 2009, May 14, 2009, September 15, 2009, January 14, 2010, May 14, 2010, September 15, 2010
Full listing of deadlines for competing applications: http://www.nlm.nih.gov/ep/Deadlines.html

Last reviewed: 17 January 2008
Last updated: 17 January 2008
First published: 20 November 2007
Metadata| Permanence level: Permanence Not Guaranteed