Myelofibrosis
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Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by fibrous (scar) tissue.[1] Scarring of the bone marrow causes anemia, which can lead to fatigue and weakness, as well as pooling of the blood in abnormal sites like the liver and spleen, causing these organs to swell.[1][2] The cause of myelofibrosis in unknown and there are no known risk factors.[1] Although myelofibrosis can occur at any age, it typically develops after the age of 50.[1][2] In most cases, myelofibrosis gets progressively worse. Treatment is aimed at relieving signs and symptoms and may include medications, blood transfusions, chemotherapy, radiation therapy and surgery.[2]
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- More Information (Found: 6 Resources)
Links where you can find more general information, comprehensive resources, selected full text journal articles, and news updates
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eMedicine provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free
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MedlinePlus, a Web site designed by the National Library of Medicine Web site to help you research your health questions, provides more information about this topic. Click on the link to view this information.
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The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
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The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Myelofibrosis. Click on the link to go to OMIM and review these resources.
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PubMed lists journal articles that discuss Myelofibrosis. Click on the link to go to PubMed and review citations to these articles.
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MayoClinic.com offers additional information about myelofibrosis. Click on the above link to access this information.
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The National Organization of Rare Disorders (NORD) has partnered with Inspire.com to launch an online community for people with rare diseases called The NORD Rare Disease Community. This community connects medical patients, family members, caregivers, and professionals. Click on The NORD Rare Disease Community to learn more.
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RareShare is an online social hub dedicated to patients, families and healthcare professionals affected by rare medical disorders. Click on RareShare to learn more.
- Research & Clinical Trials (Found: 1 Resources)
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ClinicalTrials.gov lists trials that are studying or have studied Myelofibrosis. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
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The NLM Gateway allows users to search across multiple resources offered on the National Library of Medicine's Web site. Some of these resources may be duplicated in the list of links above. Click on the link to go to the NLM Gateway, and search by condition name.