National Toxicology Program

Chloral Hydrate - TR-502

The Subcommittee accepted unanimously (6 yes votes) the conclusions as written, no increased incidences of neoplasms in female mice that received a single dose at 15 or 28 days of age or in male mice that received a single dose at 15 days of age, and recommended unanimously the conclusions, equivocal evidence of carcinogenic activity for female mice that were continuously treated for two years and no hepatic carcinogenicity under all dosing conditions.

Chloral Hydrate (Feed Restricted) - TR-503

The Subcommittee accepted (5 yes votes, 1 no) the conclusion as written, some evidence of carcinogenic activity in male mice.

p,p'-Dichlorodiphenyl sulfone - TR-501

The Subcommittee accepted unanimously (5 yes votes) the conclusions as written, no evidence of carcinogenic activity in male and female rats and in male and female mice.

Indium Phosphide - TR-499

The Subcommittee accepted unanimously (6 yes votes) the conclusions as written, clear evidence of carcinogenic activity in male and female rats and clear evidence of carcinogenic activity in male and female mice. The Subcommittee recommended that the liver be removed from clear evidence in female mice and considered also exposure related.

Naphthalene - TR-500

The Subcommittee accepted unanimously (6 yes votes) the conclusions as written, clear evidence of carcinogenic activity in male and female rats

Sodium Nitrite - TR-495

The Subcommittee accepted unanimously (6 yes votes) the conclusions as written, no evidence of carcinogenic activity in male rats and male mice, and recommended unanimously the conclusions, no evidence of carcinogenic activity in female rats and equivocal evidence of carcinogenic activity in female mice.