National Toxicology Program

Acrylonitrile -- TR-506

The Subcommittee accepted (7 yes votes, 1 abstention) the conclusions as written, clear evidence of carcinogenic activity of acrylonitrile in male and female mice.

Citral -- TR-505

The Subcommittee accepted (4 yes votes, 4 no votes; chair voted yes to break the tie) the conclusions as written, no evidence of carcinogenic activity of citral in male or female rats and in male mice, and recommended the conclusion, equivocal evidence of carcinogenic activity in female mice.

Methacrylonitrile -- TR-497

The Subcommittee accepted (5 yes votes, 1 no vote and 2 abstentions) the conclusions as written, no evidence of carcinogenic activity of methacrylonitrile in male and female rats and in male and female mice.

o-Nitrotoluene -- TR-504

The Subcommittee accepted (6 yes votes, 2 no votes) the conclusions as written, clear evidence of carcinogenic activity of o-Nitrotoluene in male and female rats and in male and female mice.

p-Nitrotoluene -- TR-498

The Subcommittee accepted unanimously (8 yes votes) the conclusions as written, equivocal evidence of carcinogenic activity of p-Nitrotoluene in male rats and in male mice, some evidence of carcinogenic activity in female rats, and no evidence of carcinogenic activity in female mice.