7:30 a.m.

Registration and Continental Breakfast

8:30 a.m.

Welcome
Dr. Christopher J. Portier, Environmental Toxicology Program (ETP),
National Institute of Environmental Health Sciences (NIEHS)
Dr. Linda Birnbaum, National Health and Environmental Effects
Research Laboratory (NHEERL), US Environmental Protection Agency (EPA)

KEYNOTE
Chair:Dr. Christopher Portier, ETP, NIEHS

8:45 a.m.

What are the issues?
Dr. Dean Metcalfe, NIAID

9:15 a.m.

Assessing the Allergenicity of Genetically Engineered Foods: Summary of a Symposium at the National Center for Food Safety and Technology
Dr. Steven Gendel, Food and Drug Administration (FDA)

SESSION I: CLINICAL ASPECTS AND CLINICAL INVESTIGATION OF FOOD ALLERGY
Chair: Dr. Lynn Goldman, Johns Hopkins University

9:40 a.m.

Clinical Spectrum of Food Allergy
Dr. Hugh Sampson, Mount Sinai School of Medicine

10:10 a.m.

Break

10:30 a.m.

Assessment of Allergenicity to Genetically Modified Food and Novel Proteins
Dr. Sam Lehrer, Tulane University Health Sciences Center

11:00 a.m.

Occupational Inhalation Allergenicity and Food Allergy
Dr. Leonard Bernstein, University of Cincinnati

11:30 a.m.

Clinical and Laboratory Methods in the Assessment of the Allergenicity of Foods
Dr. Robert G. Hamilton, Johns Hopkins University

Noon

Lunch (on your own)

1:00 p.m.

Can Post-Marketing Surveillance Provide Useful Information About the Allergenicity of Genetically Modified Foods: The StarLink Corn Experience
Dr. Carol Rubin, Centers for Disease Control and Prevention

SESSION II: TOXICOLOGICAL EVALUATION OF NOVEL PROTEINS
Chair: Dr. Dennis Hinton, FDA

1:40 p.m.

Digestion Stability as a Criterion for Protein Allergenicity Assessment
Dr. Tong-Jen Fu, FDA

2:10 p.m.

Structure and Stability of the Major Peanut Allergens
Dr. Gary Bannon, Monsanto Company

2:40 p.m.

Break

SESSION III: REGULATORY CONSIDERATIONS
Chair: Dr. Christopher Portier, ETP, NIEHS

3:00 p.m.

Short Presentations Followed by a Panel Discussion

SESSION IV: RISK COMMUNICATION -- Biotechnology and How the Public Perceives It
Chair: Dr. Dori Germolec, NIEHS

4:15 p.m.

What Consumers Think About Biotechnology
Dr. Thomas Hoban, North Carolina State University

4:35 p.m.

Public-Interest Perspective on Allergenicity
Dr. Rebecca Goldburg, Environmental Defense

5:00 p.m.

Open Discussion

5:30 p.m.

Meeting Adjourns

7:30 a.m.

Registration and Continental Breakfast

8:30 a.m.

Overview

8:40 a.m.

Oral and Intraperitoneal Exposure of Brown Norway Rats
Dr. Andre Penninks, TNO Nutrition and Food Research

9:15 a.m.

Oral and Systemic Exposure of BALB/c Mice
Dr. Ian Kimber, Syngenta

9:50 a.m..

Peanut Allergenicity in a Swine Model
Dr. Ricki Helm, University of Arkansas for Medical Services

10:25 a.m.

Break

10:45 a.m.

Assessment of Allergenicity in Dogs I
Dr. Bob Buchanan, University of California, Berkeley

11:20 a.m.

Allergenicity in Dogs II: Spontaneous Food Hypersensitivity / Allergy in a Colony of Dogs
Dr. Bruce Hammerberg, North Carolina State University

SESSION VI - BREAKOUT GROUP MEETINGS

12:00 p.m.

CHARGE TO BREAKOUT GROUPS
Dr. MaryJane Selgrade, USEPA

What are the research needs in the areas of:

1. Use of Human Clinical Data
   Chair: Dr. Charlotte Madsen, Danish Veterinary and Food Administration
2. Animal Models to Assess Food Allergy
   Chair: Dr. Oscar Frick, University of California, San Francisco
3. Biomarkers of Exposure and Effect
   Chair: Dr. Genevieve Bondy, Health Canada
4. Sensitive Populations
   Chair: Dr. Mel Dong, FDA
5. Models of Dose Response
   Chair: Dr. Robert Frederick, EPA
6. Post-market Surveillance
   Chair: Dr. Fujio Kayama, JICHI Medical School

12:15 p.m.

Lunch (on your own)

1:15 p.m.

Address Questions, Research Needs and Areas of Particular Focus
(Within Breakout Groups)

2:45 p.m.

Break

3:00-3:30 p.m.

Observer Question and Discussion Session
(Within Breakout Groups)

5:30 p.m.

7:30 a.m.

Registration and Continental Breakfast

SESSION VII - BREAKOUT GROUP PRESENTATIONS
Chairs: Dr. Lynn Goldman, Johns Hopkins Unversity & Dr. MaryJane Selgrade, EPA

8:30 a.m.

Presentations

10:30 a.m.

Break

10:50 a.m.

Presentations continued

11:15 a.m.

Meeting Summary and Discussion
Consensus Building and Agreement on the Way Forward

12:30 p.m.

Meeting Adjourns