Summaries & Associations of Study Results
TR-363 Bromoethane (Ethyl Bromide)
Target Organs and Levels of Evidence
NTP Technical Report Number 363
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| BROMOETHANE (ETHYL BROMIDE) 74-96-4 |
10/03/88 | CHEMICAL INTERMEDIATE FOR PHARMACEUTICALS. ETHYLATING AGENT IN ORGANIC SYNTHESIS. REFRIGERANT. GRAIN AND FRUIT FUMIGANT. (TDB) | Inhalation R&M: 0,100,200,400 PPM/50 PER GROUP | Battelle Northwest Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: SOME EVIDENCE | ADRENAL GLAND MEDULLA: PHEOCHROMOCYTOMA 8/48 23/47 17/50 21/49 OR MALIGNANT PHEOCHROMOCYTOMA 0/48 1/47 2/50 0/49 COMBINED 8/48 23/47 18/50 21/49 | |||
| MAY HAVE BEEN RELATED: | BRAIN: GRANULAR CELL TUMOR 0/49 3/50 1/50 1/50; GLIOMA 0/49 1/50 0/50 0/50, ASTROCYTOMA 0/49 1/50 0/50 0/50, OR OLIGODENDROGLIOMA 0/49 1/50 0/50 0/50 COMBINED 0/49 3/50 0/50 0/50 | |||
| LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 0/48 0/49 1/48 1/48 OR ALVEOLAR/BRONCHIOLAR CARCINOMA 0/48 0/49 3/48 0/48 COMBINED 0/48 0/49 4/48 1/48 | ||||
| FR: EQUIVOCAL EVIDENCE | BRAIN: GLIOMA 0/50 1/50 1/48 3/50 | |||
| LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 0/50 0/48 0/47 3/49 | ||||
| MM: EQUIVOCAL EVIDENCE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 5/50 6/50 8/50 9/50 OR ALVEOLAR/BRONCHIOLAR CARCINOMA 2/50 0/50 5/50 6/50 COMBINED 7/50 6/50 12/50 15/50 | |||
| FM: CLEAR EVIDENCE | UTERUS/CERVIX: ADENOMA 0/50 1/50 1/47 6/48, ADENOCARCINOMA 0/50 2/50 3/47 19/48, OR SQUAMOUS CELL CARCINOMA 0/50 1/50 1/47 3/48 COMBINED 0/50 4/50 5/47 27/48 | |||
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