Home » Strategic Planning » Strategies to Investigate the Pathophysiology of Ganglion Cell and Optic Nerve Degeneration--Agenda
Strategies to Investigate the Pathophysiology of Ganglion Cell and Optic Nerve Degeneration
Airlie Conference Center, Airlie, Virginia
November 12-13, 2002
Agenda
| Tuesday, November 12, 2002 | ||
| * Check-in prior to 12 noon | ||
| 12 noon - 1:00 p.m. | Lunch | |
| 1:00 p.m. - 2:15 p.m. | Current Hypotheses of Glaucoma Pathophysiology | |
| 1:00 p.m. - 1:25 p.m. | Donald Zack, M.D., Ph.D., Johns Hopkins What is glaucoma? What is the role of intraocular pressure in the etiology of glaucoma? | |
| 1:25 p.m. - 1:40 p.m. | Alan M. Laties, M.D., University of Pennsylvania What is the vascular component of glaucoma? | |
| 1:40 p.m. - 2:00 p.m. | M. Rosario Hernandez, D.D.S., Washington University What damages the optic nerve head in glaucoma? | |
| 2:00 p.m. - 2:15 p.m. | Discussion | |
| 2:15 p.m. - 3:10 p.m. | What Can Animal Models Contribute to the Study of Glaucoma? | |
| 2:15 p.m. - 2:35 p.m. | John C. Morrison, M.D., Oregon Primate and rat models of ocular hypertension | |
| 2:35 p.m. - 2:55 p.m. | Simon John, Ph.D., Jackson Labs Mouse models of inherited ON/GC degeneration | |
| 2:55 p.m. - 3:10 p.m. | Discussion | |
| 3:10 p.m. - 3:30 p.m. | Break | |
| 3:30 p.m. - 5:00 p.m. | How is the Biology of the Inner Retina Affected in Glaucoma? | |
| 3:30 p.m. - 3:55 p.m. | Ben A. Barres, M.D., Ph.D., Stanford University Retinal ganglion cell interactions and survival | |
| 3:55 p.m. - 4:20 p.m. | Carla J. Shatz, Ph.D., Harvard University Function and retinal development | |
| 4:20 p.m. - 4:45 p.m. | David Copenhagen, Ph.D., UCSF Glutamate and synaptic transmission | |
| 4:45 p.m. - 5:00 p.m. | Discussion | |
| 5:00 p.m. - 6:00 p.m. | Are Mechanisms of Chronic Neurodegeneration Relevant to Glaucoma Etiology? | |
| 5:00 p.m. - 5:25 p.m. | Jeff Rothstein, M.D., Ph.D., Johns Hopkins Amyotrophic lateral sclerosis | |
| 5:25 p.m. - 5:50 p.m. | Valina L. Dawson, Ph.D., Johns Hopkins Parkinson's Disease and Stroke | |
| 5:50 p.m. - 6:00 p.m. | Discussion | |
| 6:00 p.m. - 7:15 p.m. | Break/Dinner | |
| 7:15 p.m. - 9:00 p.m. | Degeneration/Regeneration | |
| 7:15 p.m. - 7:40 p.m. | Eugene M. Johnson, Ph.D., Washington University Growth factor deprivation and neuronal cell death. | |
| 7:40 p.m. - 8:05 p.m. | Ben A. Barres, M.D., Ph.D., Stanford Medical School What are the factors that promote RGC survival and axon regeneration? | |
| 8:05 p.m. - 8:30 p.m. | Bruce R. Ransom, M.D., Ph.D., University of Washington The optic nerve as a model of CNS ischemic damage. | |
| 8:30 p.m. - 9:00 p.m. | Discussion/Plans for Next Day | |
| Wednesday, November 13, 2002 | ||
| 7:30 a.m. - 8:30 a.m. | Breakfast | |
| 8:30 a.m. - 8:55 a.m. | What is known about the microenvironment in the optic nerve-head? | |
| 8:30 a.m. - 8:55 a.m. | Arthur H. Neufeld, Ph.D., Washington University Role of NO in RGC Degeneration | |
| 9:00 a.m. - 9:40 a.m. | Presentation on topics to be decided based on day one discussions | |
| 9:40 a.m. - Noon | Discussion Topics | |
| 9:40 a.m. - 10:10 a.m. | Can we identify key points that trigger the mechanisms of disease? Leaders: Eugene M. Johnson, Ph.D./Donald Zack, M.D., Ph.D.. | |
| 10:10 a.m. - 10:30 a.m. | Break | |
| 10:30 a.m. - 11:00 a.m. | Can we devise protective strategies for RGC? Leaders: Valina L. Dawson, Ph.D./Arthur H. Neufeld, Ph.D.. | |
| 11:00 a.m. - 11:30 a.m. | What are the key systems and models that can be explored in RGC neuroprotection? Leaders: Bruce R. Ransom, M.D., Ph.D./M. Rosario Hernandez, D.D.S.. | |
| 11:30 a.m. - Noon | Where do we go next? Leader: Ruben Adler, M.D.. | |
| Noon - 2:00 p.m. | Working lunch and Recommendations for 5 Priority Areas | |
| 2:30 p.m. | Rides to Dulles Airport to arrive by 3:30 pm for 5 pm flights. | |
| 2:30 p.m. | Rides to Reagan-National Airport to arrive by 3:45 pm for 5 pm flights. | |
