Summaries & Associations of Study Results
TR-408 Mercuric Chloride
Target Organs and Levels of Evidence
NTP Technical Report Number 408
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| MERCURIC CHLORIDE 7487-94-7 |
07/10/91 | PRESERVING WOOD. EMBALMING. BROWNING AND ETCHING STEEL AND IRON. REAGENT. CHEMICAL INTERMEDIATE. INSECTICIDE. FUNGICIDE. MORDANT FOR FURS. VETERINARY DISINFECTANT AND ANTISEPTIC. (TDB) | Gavage R: 0,2.5,5, M: 0,5,10 MG/KG/60 PER GROUP | International Research & Development Corp. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: SOME EVIDENCE | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 0/50 3/50 12/50 | |||
| MAY HAVE BEEN RELATED: | THYROID GLAND FOLLICULAR CELL: ADENOMA 1/50 4/50 0/50 OR CARCINOMA 1/50 2/50 6/50 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: NEPHROPATHY; TUBULAR HYPERPLASIA | |||
| FORESTOMACH: PAPILLARY HYPERPLASIA | ||||
| NASAL CAVITY: INFLAMMATION | ||||
| FR: EQUIVOCAL EVIDENCE | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 0/50 0/49 2/50 | |||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: PAPILLARY HYPERPLASIA | |||
| NASAL CAVITY: INFLAMMATION | ||||
| MM: EQUIVOCAL EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 0/50 2/49 OR ADENOCARCINOMA 0/50 0/50 1/49 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: NEPHROPATHY | |||
| NASAL CAVITY: OLFACTORY EPITHELIAL METAPLASIA | ||||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: NEPHROPATHY | |||
| NASAL CAVITY: OLFACTORY EPITHELIAL METAPLASIA | ||||
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