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Influenza Virus Resource presents data obtained from the NIAID Influenza Genome Sequencing Project as well as from GenBank, combined with tools for flu sequence analysis and annotation. In addition, it provides links to other resources that contain flu sequences, publications and general information about flu viruses.

Read more about: This resource | Flu database | NIAID Influenza Sequencing Project | Influenza virus biology
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Overview

The Influenza Genome Sequencing Project, funded by The National Institute of Allergy and Infectious Diseases (NIAID), aims to rapidly sequence flu viruses from samples collected from all over the world, from birds, pigs, and other animals, as well as humans. The viral sequences, which are being generated at The J. Craig Venter Institute (JCVI), are deposited in GenBank, and these data have been used to create the Influenza Virus Resource.

The main component of the Influenza Virus Resource is the NCBI Influenza Virus Sequence Database, where users can build queries, retrieve sequences, find complete genome sets, BLAST a flu sequence against the database, do multiple sequence alignment, and build clustering or phylogenetic trees.

In addition to the sequence data, this resource provides an influenza virus sequence annotation tool, as well as links to other Flu-related NCBI resources listed below.
Growth of flu sequences in GenBank
GenBank sequences from the NIAID Project
Assembly Archive
Trace Archive
NIAID data releasing status
RefSeq genomes
RefSeq proteins
Protein Structures

Links to recent publications on flu research and flu sequence updates in GenBank are also provided.

This resource enables scientists to compare influenza virus strains so that emergent variants can be more rapidly identified, and vaccines developed accordingly. As the library of viral sequences grows, it will act as a reference to help further our understanding of how avian viruses spread to humans, and how influenza activity spreads throughout the world.

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