Definition of anti-CD22 immunotoxin CAT-8015 - NCI Dictionary of Cancer Terms

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anti-CD22 immunotoxin CAT-8015 (… IH-myoo-noh-TOK-sin …)

A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of some types of B-cell cancer. Anti-CD22 immunotoxin CAT-8015 is made in the laboratory. It binds to CD22, a protein on the surface of normal B cells and B-cell tumors, and kills the cells. Also called CAT-8015.

Previous Definitions:	anthracenedione, anthracycline, anthraquinone, anti-CD19 immunotoxin, anti-CD22 immunotoxin
Next Definitions:	anti-CD45 monoclonal antibody, anti-CEA antibody, anti-EpCAM-Pseudomonas-exotoxin fusion protein, anti-idiotype vaccine, anti-IL-6 chimeric monoclonal antibody