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Breast Cancer - Featured Clinical Trials

The following list shows Featured Clinical Trials for a specific type of cancer. You may also want to view:

6.  Reactivating Tumor Suppressor Genes
(Posted: 04/17/2007) - This is the first clinical trial to test the combination of a drug called 5-fluoro-2'-deoxycytidine (FdCyd) and tetrahydrouridine (THU) in humans. Researchers are interested in establishing the maximum tolerated dose and determining how this regimen affects the activity of certain tumor suppressor genes in patients with advanced solid tumors.

7.  Neoadjuvant Treatment of Breast Cancer Using Aromatase Inhibitors
(Posted: 02/20/2007) - In this trial, women with estrogen receptor-positive breast cancer will be treated with one of three aromatase inhibitors (AI)--exemestane (Aromasin), letrozole (Femara), or anastrozole (Arimidex)--before surgery to determine which AI(s) to use in a future trial that compares neoadjuvant AI therapy and neoadjuvant chemotherapy.

8.  Trial of Four Schedules of Adjuvant Chemotherapy for Breast Cancer
(Posted: 03/30/2004, Updated: 11/22/2006) - This trial compares the effectiveness of four different treatment schedules using the drugs doxorubucin, cyclophosphomide, and paclitaxel in treating patients who have undergone surgery for stage l, ll, or lll breast cancer.

9.  Gene Therapy for Metastatic Cancer
(Posted: 11/21/2006) - In the trial, researchers will harvest normal T lymphocytes from patients' blood and modify these immune system cells to recognize p53 protein, a common hallmark of many cancers. The modified cells will be enriched in the laboratory and then infused back into the patients.

10.  Tailored Treatment for Breast Cancer
(Posted: 05/23/2006) - In this trial, doctors will use a test called the Oncotype DX Breast Cancer Assay, which measures the activity of a set of genes in breast tumor tissue, to determine which women will receive adjuvant chemotherapy in addition to hormone therapy.
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