Biosketch

Dr. Zenaide Quezado, a native of Brazil, is chief of the Department of Anesthesia and Surgical Services at the National Institutes of Health Clinical Center. During her tenure as chief, she was awarded the NIH Director’s Award for her creative leadership of anesthesia services and the Clinical Center Director’s Award for excellence in patient care.

Her research focuses on the mechanisms of transmission of nociceptive stimulus and the role of neuronal nitric oxide synthase in sepsis.

After earning her medical degree in Brazil at the Federal University of Ceara, Dr. Quezado completed an internship and residency in medicine and internal medicine at Albert Einstein Medical Center at Temple University.

Dr. Quezado first joined the NIH as a medical staff fellow in the Critical Care Medicine Department from 1990 to 1994. She then held several faculty appointments from 1994 to 1996, serving as assistant professor of medicine at Uniformed Services University of Health Sciences in Bethesda, Maryland, research associate in the Department of Clinical Investigation at Walter Reed Army Medical Center and senior research scientist at the Henry M. Jackson Foundation. In 1996, she moved to Boston to complete an anesthesia residency and fellowship at Massachusetts General Hospital. In 1999, she served as Professor of Anesthesia at Massachusetts General Hospital.

Dr. Quezado returned to NIH as a staff clinician in the Department of Anesthesia and Surgical Services in 2000 and was named chief of the department in 2003. She is an examiner with the American Board of Anesthesiology.

Honors and Awards

Intern of the Year, Upjohn Award for Excellence in Medicine, 1988; Award for Finest Original Scientific Paper, Society of Critical Care Medicine, 1993; Pennathur Sundaram, M.D., NeuroAnesthesia Award, Massachusetts General Hospital, 1996; Award for Special Services in Pediatric Anesthesia, Department of Anesthesia and Surgical Services, 2001; Clinical Center Director’s Award for Excellence in Patient Care, 2004; NIH Director’s Award, 2005.

Publications

BOOK CHAPTERS

Allain R and Quezado ZMN. Preoperative assessment of patients with hepatobiliary disease. In: Sweitzer B (ed). Handbook of Preoperative Assessment. Lippincott Williams ? Wilkins. Philadelphia, PA, 2000.

JOURNAL ARTICLES

Quezado ZMN, Wilson WH, Cunnion RE, Parker MM, Reda D, Bryant G, and Ognibene FP. High-dose ifosfamide is associated with severe, reversible cardiac dysfunction. Ann Intern Med, 118:31-36, 1993.

Quezado ZMN, Natason C, Alling DW, Banks SM, Koev CA, Elin RJ, Hosseini JM, Bacher JD, Danner RL, and Hoffman WD. A controlled trial of HA-1A in a canine model of gram-negative septic shock. JAMA, 269:2221-2227, 1993.

Quezado ZMN, Hoffman WD, Winkelstein JA, Yatsiv I, Koev CA, Cork LC, Elin RJ, Eichacker PQ, and Natanson C. The third component of complement protects against endotoxin-induced shock and multiple organ failure. J Exp Med, 179:569-578, 1994.

Quezado ZMN, Natason C, Banks SM, Alling DW, Koev CA, Danner RL, Elin RJ, Hosseini JM, Parker TS, Levine DM, Rubin AL, and Hoffman WD. Therapeutic trial of reconstituted human high density lipoprotein in a canine model of gram-negative septic shock. J Pharmacol Exp Ther, 272:604-611, 1995.

Quezado ZMN, Natason C, Karzai W, Danner RL, Koev CA, Fitz Y, Dolan DP, Richmond S, Banks SM, Wilson L, and Eichacker PQ. Cardiopulmonary effects of inhaled nitric oxide in normal dogs and during E. coli pneumonia and sepsis. J. Appl. Physiol, 84: 107-115, 1998.

Ullrich R, Scherrer-Crosbie M, Bloch KD, Ichinose F, Nakajima H, Picard MH, Zapol WM, and Quezado ZMN. Congenital deficiency of nitric oxide synthase 2 protects against endotoxin-induced myocardial dysfunction in mice. Circulation, 102:1440-1446, 2000.

Quezado Z, Parent C, Karzai W, Depietro M, Natanson C, Hammond W, Danner RL, Cui X, Fitz Y, Banks SM, Gerstenberger E, and Eichacker PQ. Acute G-CSF therapy is not protective during lethal E. coli sepsis. Am J Physiol Regulatory Integrative Comp Physiol , 281: R1177-85, 2001.

Quezado ZMN, Veihmeyer J, Schwartz L, Nwokoro NA, Porter FD. Anesthesia and airway management of pediatric patients with Smith-Lemi-Optiz syndrome. Anesthesiology 97:1015-9, 2002.

Finkel JC, Besch VG, Hergen A, Kakareka J, Pohida J, Melzer JM, Koziol D, Wesley R, and Quezado ZMN. Effects of aging on current vocalization threshold in mice measured by a novel nociception assay. In press, Anesthesiology, 2006