Recurrent Inhibitory Circuits in the Cortex |
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| Air date: | Monday, June 18, 2007, 12:00:00 PM |
| Category: | Neuroscience |
| Runtime: | 68 minutes |
| NLM Title: | Recurrent inhibitory circuits in the cortex [electronic resource] / Massimo Scanziani. |
| Series: | NIH neuroscience seminar series |
| Author: | Scanziani, Massimo. National Institutes of Health (U.S.) |
| Publisher: | [Bethesda, Md. : National Institutes of Health, 2007] |
| Other Title(s): | NIH neuroscience seminar series |
| Abstract: | (CIT): Timing is one of the basic attributes of a stimulus conveyed by sensory systems and is fundamental for accurate sensory discrimination. Accordingly, during the initial steps of sensory processing faithful transmission of the temporal properties of a stimulus is observed in several brain areas and for different sensory modalities. The spiking of neurons in the somato-sensory barrel cortex, for example, is precisely time-locked to stimuli applied to the whiskers and spiking probability depends on the velocity of the deflection. Very little is known, however, about the cellular mechanisms underlying temporal discrimination of tactile information entering the cortex. To address the cellular basis for this temporal precision Dr. Scanziani studies the interaction between inhibition and excitation in cortical circuits using electrophysiology in brain slices. His work has led to fundamental changes in understanding what roles local circuit GABAergic interneurons play in regulating co-incidence detection in excitatory neurons. His work has large impact in understanding how information is encoded and processed in cortical neuronal networks, and how the regulation of timing contributes to the mechanisms underlying experience-dependent plasticity. |
| Subjects: | Cerebral Cortex--physiology Interneurons--physiology Neural Pathways--physiology gamma-Aminobutyric Acid--physiology |
| Publication Types: | Government Publications Lectures |
| Download: | Download
Video How to download a Videocast |
| NLM Classification: | WL 102.5 |
| NLM ID: | 101310974 |
| CIT File ID: | 13906 |
| CIT Live ID: | 5838 |
| Permanent link: | http://videocast.nih.gov/launch.asp?13906 |
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Enhanced Audio Podcast | 1:00:58 |
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Enhanced Video Podcast | 1:00:58 | |