Personalizing Cancer Prevention |
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Air date: | Wednesday, April 16, 2008, 3:00:00 PM |
Category: | Wednesday Afternoon Lectures |
Runtime: | 72 minutes |
NLM Title: | Personalizing cancer prevention [electronic resource] / Alice S. Whittemore. |
Series: | NIH Robert S. Gordon, Jr. lecture |
Author: | Whittemore, Alice. National Institutes of Health (U.S.) |
Publisher: | [Bethesda, Md. : National Institutes of Health, 2008] |
Other Title(s): | NIH Robert S. Gordon, Jr. lecture |
Abstract: | (CIT): In this talk I will discuss some of the paradoxes and problems in personalizing the prevention of cancer and other chronic diseases. For example, how will individuals handle the information they receive? What are the emotional consequences of learning that you are at increased risk of a life-threatening disease? How can patients and their physicians understand and balance the risks and benefits of any given preventive strategy? What epidemiologic data are needed to help them? From a public health perspective, one might ask how individual risk prediction might be used to decrease the disease burden of a population. The attraction of personalized prevention is based on the premise that individuals have a broad spectrum of risks for a given disease, and that most of the disease burden is borne by a small subset of identifiable "high-risk" individuals. According to this premise, identifying the high-risk individuals would enable us to focus screening and chemo-prevention on those for whom it would be most effective. Is the premise valid? Some have argued against it, noting examples in which individuals deemed "high-risk" account for only a small fraction of a given disease. Even if valid, the premise involves the paradox that many individuals must undergo a given preventive strategy so that a handful can receive the benefit. I will illustrate these issues with examples from our current attempts to prevent breast and prostate cancer. |
Subjects: | Genetic Predisposition to Disease Neoplasms--epidemiology Neoplasms--prevention & control Neoplasms--psychology Risk Assessment |
Publication Types: | Government Publications Lectures |
Download: | Download
Video How to download a Videocast |
NLM Classification: | QZ 200 |
NLM ID: | 101473090 |
CIT File ID: | 14436 |
CIT Live ID: | 6219 |
Permanent link: | http://videocast.nih.gov/launch.asp?14436 |
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Enhanced Audio Podcast | 1:00:36 |
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Enhanced Video Podcast | 1:00:36 |