Adriana Marques, M.D.
Chief, Clinical Studies Unit
Description of Research Program
The Clinical Studies Unit (CSU) was created in 1997. Its main objective is the development and conduct of clinical research in areas of interest to the Laboratory of Clinical Infectious Diseases and its senior staff. Clinical projects are underway that complement molecular studies.
Major Areas of Research
- Lyme disease
- Herpes simplex virus infections
- Shingles (herpes zoster virus) infections
- Autoimmune lymphoproliferative syndrome (ALPS)
- Chronic active Epstein-Barr virus disease (CAEBV)
Research Group Members
Nuralem Endale; Rachael Fulton, R.N.; Katie Perkins, N.P.; Susan Price, R.N.; Koneti Rao, M.D.; Siu-Ping Turk, R.N.; Sonia Whittaker, L.P.N.
Current Clinical Protocols
STARI
Lyme Disease
Herpes Zoster
Epstein-Barr Virus
Herpes Simplex Virus
Autoimmune Lymphoproliferative Syndrome
Selected Publications
To view a complete listing, visit PubMed.
Marques A. Chronic lyme disease: a review. Infect Dis Clin North Am. 2008 Jun;22(2):341-60.
Rao VK. Inside Blood commentary: Taking ALPS down a Notch Blood. Blood. 2008 Jan 15;111(2):477.
Gelderblom H, Schmidt J, Londoño D, Bai Y, Quandt J, Hornung R, Marques A, Martin R, Cadavid D. Role of interleukin 10 during persistent infection with the relapsing fever Spirochete Borrelia turicatae. Am J Pathol. 2007 Jan;170(1):251-62.
Lünemann JD, Gelderblom H, Sospedra M, Quandt JA, Pinilla C, Marques A, Martin R. Cerebrospinal fluid-infiltrating CD4+ T cells recognize Borrelia burgdorferi lysine-enriched protein domains and central nervous system autoantigens in early lyme encephalitis. Infect Immun. 2007 Jan;75(1):243-51. Epub 2006 Oct 23.
Rao VK, Straus SE. Causes and consequences of the autoimmune lymphoproliferative syndrome. Hematology. 2006 Feb;11(1):15-23.
Philipp MT, Wormser GP, Marques AR, Bittker S, Martin DS, Nowakowski J, Dally LG. A decline in C6 antibody titer occurs in successfully treated patients with culture-confirmed early localized or early disseminated Lyme Borreliosis. Clin Diagn Lab Immunol. 2005 Sep;12(9):1069-74.
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