National Cancer Institute
U.S. National Institutes of Health |

NCI Home
Cancer Topics
Clinical Trials
Cancer Statistics
Research & Funding
About NCI
Pediatric Brain Tumor Consortium
    Posted: 04/07/1999    Reviewed: 01/30/2006
Page Options
Print This Page
E-Mail This Document
Quick Links
Director's Corner

Dictionary of Cancer Terms

NCI Drug Dictionary

Funding Opportunities

NCI Publications

Advisory Boards and Groups

Science Serving People

NCI Highlights
High Dose Chemotherapy Prolongs Survival for Leukemia

Prostate Cancer Study Shows No Benefit for Selenium, Vitamin E

Past Highlights
Related Pages
Brain Tumor Home Page
NCI's gateway for information about brain tumors.

Childhood Cancers Home Page
NCI's gateway for information about pediatric cancers.

The National Cancer Institute (NCI) announced on April 5, 1999, that it had awarded funds for a Pediatric Brain Tumor Consortium, a network of medical centers that will evaluate promising treatments for children with brain malignancies. The consortium is intended to speed the development of innovative, technically challenging therapies.

While approximately 60 percent of children with brain tumors survive at least five years from the time of diagnosis, this figure has improved only slightly in the past 25 years. However, new treatment possibilities are emerging (see the related National Cancer Institute news release).

Evaluation of innovative drugs and technologies is difficult for a single institution. "No one children's cancer center sees enough children with brain tumors to conduct timely clinical studies," said Malcolm Smith, M.D., in NCI's Cancer Therapy Evaluation Program. "The consortium, by involving a number of institutions in joint studies, will be able to evaluate new treatment strategies for children with brain tumors as quickly as can be safely done."

Treatments that appear effective in these initial studies can then move on to larger, definitive trials, such as those conducted through NCI's Clinical Trials Cooperative Groups. These networks of large institutions, community hospitals, and physicians conduct trials throughout the country.

For information about this and other relevant efforts, see the NCI Cancer Therapy Evaluation Program's Web page, Childhood Cancer Resources.

Back to Top

A Service of the National Cancer Institute
Department of Health and Human Services National Institutes of Health