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Alternate Title
Basic Trial Information
Trial Description
     Purpose
     Eligibility
     Treatment/Intervention
Trial Contact Information
Registry Information

Alternate Title

Chemoprevention Study of Broccoli Sprout Extract in Smokers

Basic Trial Information

Phase Type Status Age Sponsor Protocol IDs No phase specified Prevention Active Over 18 NCI JHOC-J0427 JHOC-04051801, NCT00255775

Special Category: SPORE trial

Trial Description

Purpose:

Chemoprevention is the use of certain drugs or substances to keep cancer from forming, growing, or coming back. The use of broccoli sprout extract may prevent lung cancer.

This clinical trial is studying how well broccoli sprout extract works in preventing lung cancer in smokers.

Eligibility:

Eligibility criteria include the following:

• At least 18 years old
• Smokes one pack of cigarettes a day for at least 30 years, two packs a day for at least 15 years, or three packs a day for at least 10 years
• More than 6 weeks since vitamins or herbal supplements
• For more information about the eligibility criteria for this trial, refer to the Health Professional version.

Final eligibility for a clinical trial is determined by the health professionals conducting the trial.

Treatment/Intervention:

Participants will receive broccoli sprout extract by mouth once a day for 3 weeks. They will also keep a daily diary about their eating and smoking habits for 3 weeks before, during, and for 3 weeks after finishing treatment. Participants must continue to smoke during treatment but are encouraged to quit after finishing treatment.

Important:

For more details about this trial, refer to the Health Professional version of the trial summary.

If you are interested in participating in a clinical trial, contact your doctor for a referral or call a trial contact person listed below. You may see the same contact person listed at more than one site, however, if you call the number listed you can ask to speak to the study coordinator or person involved with the specific trial you are interested in. If you have questions about cancer or clinical trials, call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). General information about clinical trials, including risks, benefits, and costs, can be found on NCI's Web site.

Trial Contact Information

Trial Lead Organizations

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Julie Brahmer, MD, Protocol chair		Ph: 410-502-7159

U.S.A.
Maryland
	Baltimore
	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
		Clinical Trials Office - Sidney Kimmel Comprehensive Cancer Center at John Hopkins	Ph:  410-955-8804
			Email: jhcccro@jhmi.edu

Registry Information
Official Title		Evaluation of the Biological Effects of Broccoli Sprout Extract in Smokers
Trial Start Date		2005-01-20
Trial Completion Date		2008-12-31 (estimated)
Registered in ClinicalTrials.gov		NCT00255775
Date Submitted to PDQ		2005-09-13
Information Last Verified		2007-01-15
NCI Grant/Contract Number		P50-CA058184, P30-CA06973