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Central Nervous System Intersections of Drug Addiction, Chronic Pain and Analgesia (R01)
Release Date: October 24, 2008
Announcement Number: RFA-DA-09-017
Application Receipt Date:
January 28, 2009
Letter of Intent Date: December 29, 2008
Funding Contact: Linda Porter, Ph.D.
Program Area: Systems and Cognitive Neuroscience
Brief Description:
The purpose of this Funding Opportunity Announcement (FOA) issued by the National Institute on Drug Abuse (NIDA) and the National
Institute of Neurological Disorders and Stroke (NINDS) is to issue a Request for Applications (RFA) to investigate CNS changes
that occur with chronic pain, and how these changes parallel those that occur with drug addiction. Of interest will be how
chronic pain changes the CNS, how analgesics of various classes impact pain-induced CNS changes, and how analgesics in the
absence of pain (some of which have abuse potential) produce CNS changes. The temporal course of these changes will also be
of interest. A focus of this research will be comparing and contrasting these CNS changes in an effort to identify shared
and unique mechanisms involved in pain, analgesia and drug abuse, as well as environmental and genetic factors that influence
these changes.
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