National Cancer Institute National Cancer Institute
U.S. National Institutes of Health National Cancer Institute
Dictionary of Cancer Terms
Send to Printer
bisphosphonate-associated osteonecrosis (bis-fos-FOH-nayt-uh-SOH-see-ay-ted OS-tee-oh-neh-KROH-sis)

 The necrosis (death) of bone tissue caused by treatment with a bisphosphonate (a drug or substance used to treat osteoporosis, bone pain caused by some types of cancer, and high blood calcium). It commonly occurs in the jaw bones. There may be pain, swelling and infection in the areas of necrosis. Also called BON.

Previous Definitions:birth canal, birth control pill, bispecific antibody, bispecific monoclonal antibody, bisphosphonate
Next Definitions:bizelesin, BL22 immunotoxin, black cohosh, black snakeroot, bladder