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This page contains brief information about cisplatin and a collection of links to more information from the National Cancer Institute (NCI), the Food and Drug Administration (FDA), and the National Library of Medicine (NLM).

US Brand Name(s):		Platinol-AQ
		Platinol
FDA Approved:		Yes

Cisplatin is approved by the Food and Drug Administration (FDA) to be used by itself to treat the following conditions:

• Bladder cancer that cannot be treated with surgery or radiotherapy.
• Ovarian cancer that has metastasized (spread to other parts of the body) and has not gotten better with other drugs.

Cisplatin is approved to be used together with other drugs to treat the following conditions:

• Advanced ovarian cancer in patients who have already had surgery.
• Metastatic ovarian cancer in patients who have already had surgery or radiotherapy.
• Testicular cancer in patients who have already had surgery or radiotherapy.
• Locally advanced squamous cell carcinoma of the head and neck (SCCHN) that cannot be treated with surgery.
• Late-stage cervical cancer that cannot be treated with surgery or radiotherapy.
• Malignant mesothelioma that cannot be treated with surgery.
• Locally advanced, advanced, or metastatic non-small cell lung cancer (NSCLC) that cannot be treated with surgery.

In addition to the uses that have been approved by the FDA, cisplatin is sometimes used alone or with other drugs to treat other types of cancer. Cisplatin continues to be studied in the treatment of many types of cancer.

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

Clinical Trial Results: Cisplatin No Better than Standard Therapy for Anal Canal Cancer (04/30/2008) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Stomach Cancer Drug, S-1, Given With Cisplatin, Shows Promise in Japanese Trial (03/12/2008) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Before Surgery May Increase Survival in Stomach Cancer (07/09/2007) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Meta-Analysis Suggests Cisplatin Superior to Carboplatin for Advanced Non-Small Cell Lung Cancer (06/19/2007) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Long-Term Data Support Cisplatin-Based Chemoradiation for Cervical Cancer (05/29/2007) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Surgery Does Not Improve Survival for Advanced Non-Small Cell Lung Cancer Patients (04/17/2007) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Patients With Esophageal Cancer May Be Able to Avoid Surgery (04/16/2007) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Impact of Intraperitoneal Chemotherapy on Quality of Life During Ovarian Cancer Treatment (02/14/2007) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: ERCC1 Expression in Lung Cancer May Predict Survival Benefit from Cisplatin (09/20/2006) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Superior to Radiation for Uterine Sarcoma (06/27/2006) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Cisplatin Improves Survival in Non-Small Cell Lung Cancer (06/04/2006) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Elderly Benefit From Chemotherapy for Early NSCLC (06/03/2006) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy During Radiation Best for Nasopharyngeal Cancer (02/15/2006) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Cisplatin Plus Topotecan Gives Advanced Cervical Cancer Patients More Time (08/17/2005) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Better Than Radiation for Advanced Endometrial Cancer (12/21/2005) - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Announcement for Preferred Method of Treatment for Advanced Ovarian Cancer - Questions and Answers (01/04/2006) - Information about the use of this drug to treat cancer.

MedlinePlus Information on Cisplatin - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This NLM patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Clinical Trials for Cisplatin - Check for trials from NCI's PDQ Cancer Clinical Trials Registry now accepting patients.

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