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The MERIT Award
 Initiated in 1987, MERIT awards provide long-term support to investigators with impressive records of scientific achievement in research areas of special importance or promise. 

    Updated: 09/10/2008
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Past Highlights
Current NCI Recipients of the MERIT Award

Baenziger, Jacques U.

Oligosaccharide Structure/Function in Recognition
Washington University

Bar-Sagi, Dafna

Mechanisms of Signal Transduction by Ras Proteins
State University of New York Stony Brook

Berk, Arnold J.

Biosynthesis of Adenovirus Early RNAs
University of California, Los Angeles

Bigner, Darell D.

Brain Tumors - Immunological and Biological Studies
Duke University

Blenis, John

Mitogenic and Oncogenic Regulation of ERK/RSK Signaling
Harvard Medical School

Botchan, Michael

Regulatory Interactions Between Tumor Viruses and Cells
University of California, Berkeley, CA

Brattain, Michael G.

Mechanism of Action of Differentiation Agents
Roswell Park Cancer Institute

Carroll, Raymond J.

Measurement Error, Nutrition and Breast/Colon Cancer
Texas A&M University, College Station, TX

Chen, David

Roles of DNA PK in DNA Double Strand Break Repair
University of Texas Southwestern Medical Center

Cheresh, David A.

Alpha v Integrins and Tumor Angiogenesis
Scripps Research Institute

Cleary, Michael L.

Molecular Pathology of Lymphoid Malignancies
Stanford University

Coffin, John M.

Retrovirus Evolution
Tufts University

Cooper, Jonathan A.

Src Family Kinases and Cell Growth Regulation
Fred Hutchinson Cancer Research Center

Croteau, Rodney B.

Biosynthesis of Taxol
Washington State University

Dalla-Favera, Riccardo

AIDS Associated Lymphoproliferative Disorders
Columbia University

Dang, Chi V.

C Myc--Transcription and Apoptosis
Johns Hopkins University

Danishefsky, Samuel J.

Synthesis of Antitumor Natural Products
Sloan-Kettering Institute for Cancer Research

Dong, Zigang, M.D., Dr.P.H.

Anticarcinogenic Mechanisms of Tea Constituents
University of Minnesota

Dove, William F.

Genes Controlling Neoplasia of the Intestinal Epithelium
University of Wisconsin Madison

Eisenman, Robert N.

Myc Oncoprotein Function
Fred Hutchinson Cancer Research Center

Essigmann, John

Intra- and Extra-Chromosomal Probes for Mutagenesis by Carcinogens
Massachusetts Institute of Technology

Evans, William E.

Pharmacogenomics of Childhood Leukemia (ALL)
St. Jude Children's Research Hospital

Fausto, Nelson

Gene Expression in Regenerating and Neoplastic Livers
University of Washington

Feinberg, Andrew P.

BWS and Embryonal Tumor Suppressor Genes On 11p15
Johns Hopkins University

Fenical, William H.

Antitumor-Antibiotics from Marine Microorganisms
Scripps Institution of Oceanography, University of California, San Diego

Giancotti, Filippo G.

Molecular Analysis of the alpha-6 beta-4 Integrin
Sloan-Kettering Institute for Cancer Research

Goff, Stephen P.

Construction and Analysis of Retrovirus Mutants
Columbia University Medical Center

Greenberg, Philip D.

Mechanisms of Murine Tumor Eradication by Immunotherapy
University of Washington

Guengerich, F. Peter

Metabolism of Carcinogenesis and Drug by Human P450
Vanderbilt University School of Medicine

Haber, Daniel

Functional Properties of the Wilm's Tumor Gene WT1
Massachusetts General Hospital

Harrison, Stephen C.

Structure and Assembly of Viruses
Harvard University

Hauer-Jensen,Martin

Molecular Pathogenesis of Radiation Enteropathy
University of Arkansas for Medical Sciences

Hayward, S. Diane

Regulation of Replication and Latency by EBV EBNAs
Johns Hopkins University

Hecht, Stephen S.

Metabolism of Carcinogenic Tobacco-Specific Nitrosamines
University of Minnesota Cancer Center

Hendrix, Mary J.

Endothelial Transdifferentiation of Invasive Tumor Cells
University of Iowa

Howley, Peter M.

Functional Analysis of the E6AP Ubiquitin Protein Ligase
Harvard University (Medical School)

Jaenisch, Rudolf

Genomic Imprinting and the Cloning of Mice
Whitehead Institute for Biomedical Research

Katzenellenbogen, John A.

Radiopharmaceuticals for Breast Tumor Imaging & Therapy
University of Illinois Urbana-Champaign

Kinzler, Kenneth W.

Genes from the FAP Locus
Johns Hopkins University

Kipps, Thomas J.

Antibody V Gene Expression B Cell Lymphocytic Leukemia
University of California San Diego

Klagsbrun, Michael

Characterization of Neuropilin, A Novel VEGF Receptor
Children's Hospital (Boston)

Kohwi-Shigematsu, Terumi T.

Non B DNA Structure with Chemical Carcinogens
University of California-Lawrence Berkeley Lab

Kolonel, Laurence

Multiethnic Cohort Study of Diet and Cancer
Cancer Research Center of Hawaii, University of Hawaii

Korc, Murray, M.D.

Dysregulation of TGF Beta Action Pancreatic Cancer
Dartmouth College

Kornfeld, Stuart A.

Structure, Biosynthesis and Function of Glycoproteins
Washington University

Korsmeyer, Stanley J.

Protein Interaction Extends the Cell Death Pathway
Dana-Farber Cancer Institute

Laimins, Laimonis A.

Life Cycle of Oncogenic Papillomaviruses
Northwestern University

Lee, Eva Y.

Oncogenes and Loss of ER in a New p53 Breast Tumor Model
University of California Irvine

Levy, Ronald

Antiidiotype Therapy of Human B Cell Malignancy
Stanford University

Lieber, Michael R.

Human V(D)J Recombinase in Neoplastic and Primary Cells
Massachusetts Institute of Technology

Lin, Xihong

Statistical Methods for Correlated and High-Dimensional Biomedical Data
Harvard School of Public Health

Lippard, Stephen J.

Chemistry and Biology of Platinum Anticancer Drugs
Massachusetts Institute of Technology

Livingston, David M.

Structure and Function of SV40 Non-Virion Proteins
Dana-Farber Cancer Institute

Marnett, Lawrence J.

Chemistry and Biology of Malondialdehyde DNA Adducts
Vanderbilt University, Nashville, TN

Martin, G. Steven

Genetics of RNA Tumor Viruses
University of California Berkeley

Massague, Joan

Transforming Growth Factor-Beta Signal Transduction
Memorial Sloan-Kettering Cancer Center, New York, NY

Metcalf, Donald

Differentiation of Granulocytes and Macrophages
Walter and Eliza Hall Institute for Medical Research, Victoria, Australia

Miller, I. George

Studies of Epstein-Barr Virus
Yale University

Moscicki, Anna-Barbara

Natural History of HPV Infection to Neoplasia
University of California, San Francisco, CA

Murre, Cornelis

E Protein and B Cell Differentiation
University of California, San Diego

Myers, Andrew G.

Natural and Non-natural Antiproliferative Agents
Harvard University

Neel, Benjamin G.

Signal Transduction by Non-transmembrane PTPs
Beth Israel Deaconess Medical Center, Harvard University

Oren, Moshe

Functional Analysis of the p53 Tumor Suppressor
Weizmann Institute of Science

Pagano, Michele

F-Box Proteins: Deregulated Cell Cycle Control and Proteolysis in Cancer
New York University School of Medicine, NY

Pandolfi,Pier Paolo

PML, PLZF and NPM in the Molecular Pathogenesis of APL
Memorial Sloan-Kettering Cancer Center, New York, NY

Pegg, Anthony

Persistence of Alkylated DNA in Carcinogeneis
Pennsylvania State University, PA

Perucho, Manuel

Molecular Pathogenesis of Cancer of Mutator Phenotype
Burnham Institute

Prakash, Satya

Repair of UV Irradiated DNA: Excision Genes of Yeast
University of Texas Medical Branch Galveston

Privalsky, Martin

Mechanism of Action of the v-erb A Oncogene of AEV
University of California Davis

Prives, Carol L.

Regulation of the p53 Tumor Suppressor Protein
Columbia University New York Morningside

Rao, Anjana

bZIP Proteins and Lymphocyte Gene Induction
Center for Blood Research

Raz, Avraham

The Role of Tumor Cell Surface Lectin in Metastases
Wayne State University

Rich, Alexander

The Molecular Structure of Nucleic Acids
Massachusetts Institute of Technology

Roizman, Bernard

Dissection of the Functions of Herpes Simplex Virus ICP0
University of Chicago

Rosen, Jeffrey M.

Hormonal Regulation of Breast Cancer
Baylor College of Medicine

Shannon, Kevin

Translation Investigation of KRas & NF1 in Myeloid Leukemia
University of California at San Francisco

Sprent, Jonathan

Lymphocyte Function in Normal and Chimeric Mice
Scripps Research Institute

Springer, Timothy A.

Lymphocyte Function Associated Antigens
CBR Institute for Biomedical Research, Harvard University

Stanley, E. Richard

Regulation of Granulocyte and Macrophage Production
Yeshiva University

Tjian, Robert

SV40 Tumor Antigen
University of California Berkeley

Tonks, Nicholas K.

Protein Tyrosine Dephosphorylation & Signal Transduction
Cold Spring Harbor Laboratory

Vogelstein, Bert

Molecular Genetic Analysis of Colorectal Cancers
Johns Hopkins University

Wands, Jack R.

Pathogenesis, Immunodiagnosis and Therapy of HCC
Rhode Island Hospital (Providence, RI)

Wang, Jean Y.

Nuclear Function of the cAbl Protooncoprotein
University of California San Diego

Wender, Paul A.

Synthetic Studies Related to Cancer Research/Treatment
Stanford University

White, Eileen

Function of the Adenovirus E1B Oncogene
Rutgers The State University of New Jersey

Wills, John W.

Molecular Analysis of the Retroviral Budding Mechanism
Pennsylvania State University Hershey Medical Center

Yarden, Yosef

Next Generation Strategies to Intercept ErbB Signaling
Weizmann Institute, Rehovot, Israel

Zalutsky, Michael R.

Astatine and Iodine Radiolabeled Monoclonal Antibodies
Duke University

Zetter, Bruce R.

Modulators of Prostate Cancer Metastasis
Children's Hospital (Boston)

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