| Federal Register Notice 3/20/00 |
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DEPARTMENT OF HEALTH AND HUMAN SERVICES PUBLIC HEALTH SERVICE National Toxicology Program; National Institute of Environmental Health Sciences; Center for the Evaluation of Risks to Human Reproduction solicits comments on eleven chemicals being considered for further evaluation by the Center; solicits nominations of other chemicals for future consideration; and describes the Center’s evaluation process. Background The National Toxicology Program (NTP) and the National Institute of Environmental Health Sciences have established the NTP Center for the Evaluation of Risks to Human Reproduction (63 FR 68782, No 239). The purpose of the Center is to provide timely and unbiased, scientifically sound evaluations of human and experimental evidence for adverse effects on reproduction, including development, caused by agents to which humans may be exposed. The goals of the individual assessments are to (1) interpret for and provide to the general public information about the strength of scientific evidence that a given exposure or exposure circumstance poses a hazard to reproduction and the health and welfare of children: (2) provide regulatory agencies with objective and scientifically credible assessments of reproductive/development health effects associated with exposure to specific chemicals or classes of chemicals, including descriptions of any uncertainties associated with the assessment of risks, and (3) identify knowledge gaps to help establish research and testing priorities. Chemicals Recommended for Further Consideration The CERHR Core Committee, made up of representatives of NTP-participating agencies, reviewed chemical nominations for further study and recommended the following eleven chemicals for further consideration. Dossiers will be prepared on these chemicals reviewing information on their use, production volume, and general, reproductive, and developmental toxicity. Selection of candidate chemicals will be based upon production volume, extent of human exposures, public concern about chemical hazard, published evidence of reproductive or developmental toxicity, and evaluation of any additional information submitted by the public in response to this announcement. The chemicals to be considered for Expert Panel evaluation in the year 2000 are listed below with their Chemical Abstracts Service registry numbers (where available). 1-Bromopropane (106-94-5) Request for Public Comment on Candidate Chemicals The Center invites public comment on the candidate chemicals listed above, including toxicology information from completed or ongoing studies, and information on planned studies, as well as current production data, human exposure information, use patterns, and environmental occurrence. Written comments received by May 4, 2000 will be considered in the review. Please forward comments and chemical information to: Dr. John Moore, CERHR, 1800 Diagonal Road, Suite 500, Alexandria, VA 22314-2808, Phone: (703) 838-9440. Request for Nominations for Future Reviews Nominations of chemicals for future evaluations are also encouraged. Any individual or organization may nominate. Nominations should include the chemical name, Chemical Abstract Service registry number (if known), reason for the nomination, and references or articles on the chemical, when possible. The nominator's name, address, telephone number and e-mail address should be included with the nomination. Nominations can be made through the Center's web site or by mail to Dr. John Moore at the address listed above. Review Process The Center's review process is outlined below:
This page last updated: 08/24/04 |