| Monday, March 17 |
9:30 AM-12:30 PM Exhibit Hall
Bioinformatics and Computational Toxicology |
| Poster Board 531. The use of gene expression data from multiple exposure times for the development of genomic biomarkers of carcinogenic potential. R. R. Shah; S. S. Auerbach; R. D. Irwin |
1:00 PM-4:30 PM, Exhibit Hall
Genetic Polymorphisms |
| Poster Board 307. Genetic risk factors in progressive massive fibrosis in coal miners. B. Yucesoy; V. J. Johnson; K. Fluharty; M. L. Kashon; J. Slaven; G. Kissling; D. Germolec; V. Vallyathan; M. I. Luster |
1:00 PM-4:30 PM, Exhibit Hall
Safety Assessment, Non-Pharmaceutical |
| Poster Board 547. Toxicity and carcinogenicity of chromium following chronic oral exposure: dependence on valence state and tissue uptake. M. D. Stout; B. J. Collins; R. A. Herbert; A. Nyska; G. E. Kissling; K. Levine; G. T. Ross; C. D. Hébert; G. S. Travlos; J. R. Bucher; M. J. Hooth |
| Poster Board 548. Tissue distribution of chromium in male Fischer 344 rats and female B6C3F1 mice exposed to sodium dichromate dihydrate in drinking water for 2 years. B. J. Collins; K. Levine; G. T. Ross; R. Fernando; T. R. Fennell; G. E. Kissling; M. D. Stout; M. J. Hooth |
| Poster Board 549. Tissue distribution of chromium in male Fischer 344 rats and female B6C3F1 mice exposed to chromium picolinate monohydrate in the diet for 2 years. R. Fernando; K. Levine; B. J. Collins; G. E. Kissling; M. J. Hooth; T. R. Fennell; G. T. Ross; M. D. Stout |
| Poster Board 546. Carcinogenesis studies of cresols in rats and mice. J. M. Sanders; J. R. Bucher; J. C. Peckham; G. E. Kissling; M. R. Hejtmancik; R. S. Chhabra |
1:00 PM-4:30 PM, Exhibit Hall
Stem Cell Biology and Toxicology |
| Poster Board 206. Differential inflammatory gene expression in young and aged mice during chemical injury-induced hippocampal neurogenesis. C. A. McPherson; M. Aoyama; S. F. Grissom; J. Gohlke; G. J. Harry |
1:30 PM-1:45 PM, 6E, Convention Center,
Symposium Session |
| 562. Environmental influence on female puberty and breast tumorigenesis. E. A. Maull; S. Lynch; D. Winn; G. Collman; L. Reinlib |
2:45 PM-3:45 PM, 4C-4, Exhibit Hall,
NTP Exhibitor Hosted Session |
| Public access to the National Toxicology Program: From acrylamide to zinc. N. Walker |
3:57 PM-4:15 PM, 2A, Convention Center
Platform Session Frontiers in Liver Toxicology Research |
| 627. COX-2 KO mice are susceptible to sPLA2-mediated progression of acetaminophen hepatotoxicity. H. M. Mehendale; V. S. Bhave; S. Donthamsetty; J. R. Latendresse; M. Cunningham |
| Tuesday, March 18 |
9:00 AM-12:30 PM, Exhibit Hall
Alternatives to Mammalian Models |
| Poster Board 514. Modeling the effects of chlorpyrifos on Caenorhabditis elegans growth and development. W. A. Boyd; M. V. Smith; G. E. Kissling; S. J. McBride; J. R. Rice; D. W. Snyder; C. J. Portier; J. H. Freedman |
| Poster Board 527. ICCVAM recommendations on the use of five in vitro pyrogen test methods for assessing the potential pyrogenicity of pharmaceuticals and other products. R. McFarland; M. Wind; J. Kulpa-Eddy; R. Tice; W. Stokes |
| Poster Board 534. In vitro cytotoxicity test methods for estimating rat acute oral toxicity: Prediction of GHS acute oral hazard categories. M. Paris; J. Strickland; S. Casati; R. Tice; W. Stokes |
| Poster Board 535. An alternative use of in vitro cytotoxicity test data to determine when rat acute oral toxicity testing should start with the limit test. J. Strickland; M. Paris; D. Allen; R. Tice; W. Stokes |
1:00 PM-4:30 PM, Exhibit Hall
Applications of Biological Modeling |
| Poster Board 237. A discrete time model to analyze the effects of toxicants on the growth of C. elegans nematodes in a medium throughput setting. M. Smith; W. Boyd; S. McBride; G. Kissling; J. H. Freedman; C. Portier |
1:00 PM-4:30 PM, Exhibit Hall
Regulation/Policy |
| Poster Board 206. The NICEATM-ICCVAM Five Year Plan: Creating a path forward to reduce, refine and replace animal testing. A. Poland; M. Wind; W. Stokes; D. Allen; S. Fitzpatrick; J. Kulpa-Eddy; D. Hattan; A. Jacobs; D. McCarley; A. Rispin; M. Snyder; C. Sprankle; R. Tice; D. Winters |
1:30 PM-1:45 PM, 608, Convention Center
Workshop Session |
| 1278. Host susceptibility and chemical safety testing: New approaches to estimate risks in the human population. I. Rusyn; J. E. French |
1:35 PM-2:05 PM, 6B, Convention Center
Workshop Session - Molecular Mechanisms and Molecular Biology of Metal Carcinogenesis |
| 1285. Molecular toxicology of transition metals: From yeast to man. J. H. Freedman |
1:45 PM-2:15 PM, 608, Convention Center
Workshop Session - Host Susceptibility and Chemical Safety Testing: New Approaches to Estimate Risks in the Human Population |
| 1279. Genetic variation and individual susceptibility to environmental exposure and disease. J. E. French |
2:00 PM-3:30 PM, 210, Convention Center
Informational Session |
| National Institute of Environmental Health Sciences: Information meeting for students seeking postdocs. K. Olden |
| Wednesday, March 19 |
7:30 AM-8:50 AM, 608, Convention Center
Roundtable Session |
| 1328. Toxicology training needs: New faces and new tools for the 21st century. W. Slikker; J. Bucher |
9:00 AM-12:30 PM, Exhibit Hall
Application of -Omics Research Tools in Toxicology |
| Poster Board 509. Age-related hepatic gene expression alterations in immune system pathways in the Fischer Rat. R. Frawley; D. Germolec; E. K. Lobenhofer; J. Parker; G. Boorman; R. Irwin |
| Poster Board 517. Global transcriptome changes in HepG2 cells exposed to copper. M. Song; J. H. Freedman |
9:00 AM-12:30 PM, Exhibit Hall
Metals I |
| Poster Board 549. MTF-1 and CARM1 may cooperate to regulate metallothionein expression and metal homeostasis. Braithwaite; J. Freedman |
| Poster Board 553. Caenorhabditis elegans gene, Numr-1, assembles into nuclear stress granules after cadmium treatment. B. Tvermoes; J. H. Freedman |
| Poster Board 609. Increased skin carcinoma formation in adult mice associated with distorted stem cell dynamics after in utero arsenic exposure. M. Waalkes; J. Liu; D. R. Germolec; J. M. Ward; R. E. Cannon; C. S. Trempus; R. W. Tennant; B. A. Diwan |
9:00 AM-12:30 PM, Exhibit Hall
DNA Damage and Repair: Mechanisms and Agents |
| Poster Board 650. Growth arrest, DNA repair, and transcriptomic response to DNA damage in Caenorhabditis elegans. J. N. Meyer; W. A. Boyd; T. L. Crocker; D. W. Lehmann; A. M. Rodriguez; S. J. McBride; J. H. Freedman; B. Van Houten |
| Poster Board 653. Repair of radiation induced DNA strand breaks in p53 deficient and wild-type mouse hematopoietic stem cells is strain dependent. J. E. French; V. I. Parron |
9:00 AM-12:30 PM, Exhibit Hall
Nanoparticles: Inhalation and Respiratory Cell Injury |
| Poster Board 325. Carbon nanotubes and bacterial lipopolysaccharide (LPS) act coordinately to stimulate platelet-derived growth factor (PDGF) signaling and lung fibrosis in rats. M. F. Cesta; J. P. Ryman-Rasmussen; D. G. Wallace; J. C. Bonner |
9:00 AM-12:30 PM, Exhibit Hall
Respiratory and Skin Hypersensitivity |
| Poster Board 209. Performance characteristics of the local lymph node assay (LLNA) limit dose procedure. W. Stokes; D. Allen; T. Burns; N. Choksi; J. Matheson; A. Jacobs; R. Tice |
11:05 AM-11:25 AM, 2A, Convention Center
Platform Session -Mechanisms of Reproductive Toxicity |
| 1388. In vivo metabolites of DE-71 are estrogenic in vitro. M. Mercado-Feliciano; R. M. Bigsby |
12:00 PM-1:20 PM, 6B, Convention Center
Platform Session |
| National Institute of Environmental Health Sciences. Meet the Directors: The NIEHS Strategic Plan. S. Wilson; C. Walker; W. Suk; D. Lang |
1:00 PM-4:30 PM, Exhibit Hall
Biomarkers: Methods |
| Poster Board 228. Molecular dosimetry of the vinyl chloride-induced DNA adduct, 7-oxoethylguanine. E. Mutlu; Y. Jeong; G. Boysen; P. B. Upton; L. Collins; M. D. Stout; J. A. Swenberg |
1:30 PM-1:45 PM, 6C, Convention Center
Symposium Session |
| 1970. Nanomaterial pharmacokinetics and pharmacokinetic modeling: Where we are and where we need to go. N. Walker |
4:30 PM-4:44 PM, 6C, Convention Center
Informational Seminar Session |
| 2043. NIEHS Outstanding New Environmental Scientists (ONES) Awardees. J. P. Mastin; C. Shreffler |
| Thursday, March 20 |
8:30 AM-12:00 PM, Ballroom C&E
Convention Center Method Development, Autoimmunity and Disease Mechanisms in Immunotoxicology |
| Poster Board 228. Genistein protects female nonobese diabetic (NOD) mice from developing Type 1 diabetes. T. L. Guo; D. R. Germolec; W. Auttachoat; J. F. Zheng; K. L. White Jr. |
8:30 AM-12:00 PM, Ballroom C&E
Convention Center Chemoprevention |
| Poster Board 313. Decreased incidences of neoplasms and non-neoplastic lesions in F344/N rats and B6C3F1 mice fed milk thistle extracts for two years. B. Singh; A. Nyska; J. Roycroft; D. E. Malarkey; J. Dunnick |
8:30 AM-12:00 PM, Ballroom C&E
Convention Center Metals II |
| Poster Board 147. Heterologous expression system in yeast revealed structure-function relationship in metal transcription factor, MTF-1. Y. Jin; H. Al-Refai; J. Freedman |
8:30 AM-12:00 PM, Ballroom C&E
Convention Center Food Safety II |
| Poster Board 422. Fumonisin B1 exposure phenocopies cholesterol deprivation in C. elegans. M. McElwee; A. Wise; W. A. Boyd; J. H. Freedman |
8:30 AM-12:00 PM, Ballroom C&E
Convention Center Oxidative Injury and Redox Biology II: In Vitro |
| Poster Board 116. Procainamide, but not N-acetylprocainamide, induces protein radical formation on myeloperoxidase: A potential mechanism of agranulocytosis. A. Siraki; L. Deterding; M. G. Bonini; J. Jiang; M. Ehrenshaft; R. P. Mason |
11:05-11:45 AM, 615, Convention Center
Symposium Session -Cellular Redox Status and Zinc Signaling |
| 2331. Regulation of metal-inducible transcription by a zinc-finger transcription factor. J. H. Freedman; E. K. Braithwaite; Y. Jin |
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