AIDSinfo E-News: Offering HIV/AIDS Research, Clinical Trials, Prevention, and Treatment Information. | |
AIDSinfo At-a-Glance Issue No. 28July 13 , 2006
First One-Pill, Once-a-Day
Treatment for HIV/AIDS Approved Yesterday Wednesday, July 12, 2006,
the Food and Drug Administration (FDA) announced approval of Atripla
tablets, a fixed-dose combination of three widely-used antiretroviral
drugs (
Sustiva,
Emtriva, and
Viread). The
approval of Atripla is especially significant because it simplifies the
treatment regimen for HIV-1 infected adults and can help patients adhere
to treatment, resulting in long-term effective control of HIV-1. It will
also afford a more accessible treatment option to patients in developing
countries. Read more in the complete FDA
release. Reverset Trials Halted;
Investigational NRTI’s Future Unclear Development of the
nucleoside reverse transcriptase inhibitor (NRTI) dexelvucitabine,
also known as Reverset or DPC 817, has been discontinued by the licensed
manufacturer, Incyte Corp. During a Phase II trial evaluating
dexelvucitabine monotherapy, 40% of patients receiving dexelvucitabine 200
mg daily experienced Grade 4 hyperlipasemia (abnormally high blood levels
of the lipase enzyme), possibly reflecting damage to the pancreas. All
trials have been halted. Pharmasset, Inc, which owns the rights to
dexelvucitabine, has not yet decided to progress with or withdraw further
study of the drug. To see a list of other NRTIs
in clinical development, with links to both professional and patient fact
sheets in English and Spanish, click here. Check Out the AIDSinfo Travel
Page Preparing
to travel can present challenges for even the most seasoned travelers.
People living with HIV/AIDS face the additional tasks of protecting
themselves from travel-related pathogens and adhering to anti-HIV
treatment on an altered schedule. AIDSinfo has updated our HIV & Travel
page. We hope this page will be useful in planning successful trips here
in the United States and abroad. Bon Voyage!
ClinicalTrials.gov Info
New HIV/AIDS trials have been added to ClinicalTrials.gov
in the last 7 days:
click here. Please send comments or suggestions to ContactUs@aidsinfo.nih.gov
ISSN 1558-3228 |
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