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Developmental Toxicity

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Documents may also be found via the Agency Guidelines and Regulations Search Page

American Society for Testing and Materials

The following Standards can be purchased online at the ASTM Store
  • ASTM E691-99: Standard Practice for Conducting an Interlaboratory Study to Determine the Precision of a Test Method (10 May 1999)
  • ASTM E1439-98: Standard Guide for Conducting the Frog Embryo Teratogenesis Assay-Xenopus (FETAX) (10 June 1998)

U.S. Environmental Protection Agency

  • Office of Prevention, Pesticides and Toxic Substances (OPPTS) Health Effects Test Guidelines
    • OPPTS 870.3550: Reproduction/Developmental Toxicity Screening Test (July 2000) [PDF]
    • OPPTS 870.3650: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (July 2000) [PDF]
    • OPPTS 870.3700: Prenatal Developmental Toxicity Study (August 1998) [PDF]
    • OPPTS 870.3800: Reproduction and Fertility Effects (August 1998) [PDF]
  • Federal Register
    • 40 CFR 136: Whole Effluent Toxicity: Guidelines Establishing Test Procedures for the Analysis of Pollutants [PDF]










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