 |
|
metformin hydrochloride
The hydrochloride salt of the biguanide metformin with antihyperglycemic activity. Metformin decreases hepatic gluconeogenesis and intestinal absorption of glucose. This agent also increases the number and/or affinity of insulin receptors on muscle and adipose cells, increasing the sensitivity to insulin at receptor and post-receptor binding sites and increasing glucose uptake peripherally. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Glucophage | | | | Chemical structure names: | | - 1,1-dimethylbiguanide hydrochloride
- N,N-dimethylimidodicarbonimidic diamide monohydrochloride
| | |
|
|
