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tositumomab A murine IgG2 monoclonal antibody directed against the CD20 antigen, found on the surface of B-cells. Tositumomab binds to the CD20 surface membrane antigen, resulting in apoptosis, and may stimulate antitumoral cell-mediated and/or antibody-dependent cytotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | anti-B1 anti-B1 monoclonal antibody Anti-CD20 Antibody | | | Abbreviation: | | MOAB anti-B1 | | |
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