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perillyl alcohol
A naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | dihydrocuminyl alcohol
perilla alcohol
perillic alcohol
perillol | | | | Abbreviation: | | POH | | | | Chemical structure names: | | - (S)-(-)-perillyl alcohol
- 1-cyclohexene-1-methanol
- 4-(1-methylethenyl)-1-cyclohexene-1-methanol
- 4-isopropenylcyclohex-1-ene-1-methanol
- p-mentha-1,8-dien-7-ol
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